NR565 Advanced Pharmacology Final Exam Study Guide 2026 Update

NR565 – Advanced Pharmacology Fundamentals Exam Study Guide – Final Exam Exam Format: Non-Cumulative Exam Question Type: Multiple Choice Number of Questions: 100 Time Allotted: 120 minutes (1.2 minutes per question) Testing Timeframe: The final exam will be available starting on Wednesday Week 8 at 12:01 am MT until Saturday Week 8 at 11:59 pm MT. 1. Exam Coverage Content Areas: • Week 5: Pharmacotherapy for Endocrine Disorders • Week 6: Pharmacotherapy for Respiratory Conditions • Week 7: Pharmacotherapy for Gastrointestinal Conditions • Week 8: Complementary and Alternative Therapies 2. Key Concepts to Study Week 5: Pharmacotherapy for Endocrine Disorders, Chapters 48-49 Radioactive iodine adverse effects Iodism – can lead to corrosive injury to the GI tract Brassy taste Burning sensation in mouth Soreness in gums/teeth Severe abdominal distress Methimazole indication and MOA Indications: First line drug for hyperthyroidism – inhibits thyroid hormone synthesis-preferred treatment in pregnant/breastfeeding patients and those with thyrotoxic crisis MOA: Reduction of graves disease – controls hyperthyroidism – suppression of thyroid hormone until thyroidectomy – treatment of thyrotoxic crisis Levothyroxine education, population considerations, monitoring, drug interactions, dosing, adjustments Used for hypothyroidism – also used for congenital hypothyroidism, myxedema coma, simple goiter and primary hypothyroidism – insufficient TSH and TRH – used to maintain levels after thyroid surgery, irradiation, and treatment with antithyroid drugs. Education: take on empty stomach 30-60 minutes before breakfast Population: caution with cardiovascular patients – start low with elderly Monitoring: check TSH every 6-8 weeks after initiating therapy or dosing change- and once a year after stabilization Drug interactions: overdose my cause thyrotoxicosis -s/s tachycardia, angina, tremors, nervousness, insomnia, hyperthermia, sweating – accelerated bone loss, risk of a fib. Dosing: prolonged half life – last seven days – takes 1 month for plateau Pioglitazone contraindications **decrease insulin resistance – decreases glucose production by liver **black box warning Severe heart failure DKA History of bladder cancer Type I DM Hematuria hypersensitivity to drugs Hepatic impairment