complete solution.
abused prescription drug, second-most - (Correct Answer) codeine
Act also known as the Controlled Substance Act (1970) - (Correct Answer)
Comprehensive Drug Abuse Prevention and Control Act
actiq - (Correct Answer) transmuscosal fentanyl only approved for breakthrough
cancer pain in opioid tolerant patients
addictive drugs all activate the brain's _________ - (Correct Answer) dopamine
reward circuit
after detox, an opioid addict can be rx'd ___________ to discourage renewed
opioid abuse - (Correct Answer) naltrexone
AIDS patients use Dronabinol (marinol) - (Correct Answer) for appetite stim
alvimopan - (Correct Answer) used for tx of opioid-induced ileus
amphetamines are schedule - (Correct Answer) II
amphetamines work primarily by promoting neuronal release of _________ &
___________, and partly by blocking their reuptake - (Correct Answer)
norepinephrine; dopamine
amphetamines, most common adverse effects - (Correct Answer) insomnia;
weight loss
analgesics, most effective available - (Correct Answer) opioids
avinza - (Correct Answer) extended release morphine
barbiturate OD antidote? - (Correct Answer) none, just supportive treatment
barbiturate OD produces same classic triad of symptoms (resp. depression,
coma, pinpoint pupils) as seen with - (Correct Answer) opioid OD
barbiturate tolerant individuals are cross-tolerant to other CNS depressants
(alcohol, benzos, general anesthetics) but not with ________ - (Correct Answer)
opioids
, behavior pattern characterized by continued use of a psychoactive substance
despite physical, psychologic, or social harm - (Correct Answer) addiction
benzodiazepine principal indications are - (Correct Answer) anxiety, insomnia,
seizure disorders
benzodiazepines adverse effects - (Correct Answer) daytime sedation;
anterograde amnesia
benzodiazepines are classified as Schedule - (Correct Answer) IV
benzodiazepines are primarily for which two anxiety d/o's - (Correct Answer)
panic disorder, GAD
benzodiazepines produce their actions by enhancing the effects of _____, the
principal inhibitory neurotransmitter in the CNS - (Correct Answer) GABA
benzodiazepines-like controlled substace approved for long-term use in
insomnia - (Correct Answer) eszopiclone (Lunesta)
black box warnings - (Correct Answer) a component of REMS
bridging agents commonly abused - (Correct Answer) methadone, tramadol,
buprenorphine (suboxone)
buprenorphine formulations used in management of opioid addiction - (Correct
Answer) subutex or suboxone SL
butorphanol (stadol) and nalbuphne (nubain) are contraind. In MI as they -
(Correct Answer) increase cardiac work
butrans transdermal sites must be rotated. No site may be reused within ___
days - (Correct Answer) 21
cancer pain - (Correct Answer) frequently undertreated, able to be mitigated in
90% of cases with proper dosing/drug therapy (consider adjuvants)
chronic opioid therapy candidates can be identified with - (Correct Answer) ORT
(opioid risk tool); SOAPP (screener and opioid assessment for patients with
pain); DIRE (diagnois, intractability, risk, and efficacy score)
chronic opioid therapy fails - (Correct Answer) 50-70% of the time
code of fed regulations, title 21, section 1306 governs - (Correct Answer)
issuance & filling of prescriptions