Part I: Basic Immunologic Mechanisms
t t t t
1. Highlights of Innate and Adaptive Immune Systems
t t t t t t
2. Soluble Mediators of the Immune System
t t t t t
3. Antigens and Antibodies t t
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
t t t t t t t t t
Part II: The Theory of Immunologic and Serologic Procedures
t t t t t t t t
5. Basic Safety in the Immunology-Serology Laboratory
t t t t t
6. Quality Assurance and Quality Control Practices
t t t t t
7. Basic Serologic Laboratory: Techniques and Clinical Applications
t t t t t t
8. Precipitation and Particle Agglutination Methods t t t t
9. Electrophoresis Techniques t
10. Labeling Techniques in Immunoassay t t t
11. Flow Cytometry t
12. Molecular Laboratory Techniques t t
Part III: Immunologic Manifestations of Infectious Diseases
t t t t t t
13. Infectious Diseases: Overview & TORCH Diseases t t t t t
14. Streptococcal Infections t
15. Syphilis
16. Vector-Borne Diseases t
17. Infectious Mononucleosis t
18. Viral Hepatitis t
Part IV: Immune Disorders
t t t
19. Primary and Acquired (Secondary) Immune Deficiencies
t t t t t
20. Hypersensitivity Reactions t
21. Immunoproliferative Disorders t
22. Tolerance, Autoimmunity and Autoimmune Disorders t t t t
23. Systemic Lupus Erythematosus t t
,24. Rheumatoid Arthritis t
Part V: Transplantation & Tumor Immunology
t t t t t
25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
t t t t t t t
26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
t t t t t t t t
Part VI: Vaccines
t t
27. Primer on Vaccines t t
Chapter 01: Highlights ofthe Innate andAdaptive Immune Systems
t t t t t t t t t
MULTIPLE CHOICE t
1. The―father‖ofimmunologyisgenerallyconsideredto be
t t t t t t t t
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B t
, Louis Pasteur is generally considered to be the ―father of immunology.‖
t t t t t t t t t t
DIF: Cognitive Level: I t t
2. An early form of immunization was practiced by the
t t t t t t t t
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. t
ANS: C t
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried powders
t t t t t t t t t t t t t t
derived from the crusts of smallpox lesions.
t t t t t t t
DIF: Cognitive Level: I t t
3. A specific function of the immune system is to
t t t t t t t t
a. recognize self from nonself. t t t
b. defend the body against nonself. t t t t
c. amplify specific functions. t t
d. Both A and B. t t t
ANS: D t
The function ofthe immune system is to recognize self from nonself and defend the body against
t t t t t t t t t t t t t t t t
nonself. Such a system is necessary for survival. The immune system also has nonspecific
t t t t t t t t t t t t t t
effector mechanisms that usually amplify the specific functions. Nonspecific components ofthe
t t t t t t t t t t t t
immune system include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble
t t t t t t t t t
factors (e.g., complement).
t t t
DIF: Cognitive Level: I t t
4. An undesirable consequence of immunity is
t t t t t
a. natural resistance. t
b. acquired resistance to infectious diseases. t t t t