NUR 4380 - Peds Exam 3 Study Guide.

NUR 4380 - Peds Exam 3 Study Guide/NUR 4380 - Peds Exam 3 Study Guide. Immunology and Rheumatology - Anaphylaxis (pg. 754) o Acute clinical syndrome resulting from interaction of an allergen in a hypersensitive patient o Prevention of reaction is primary goal (family history) o Pathophysiology: result of an interaction between an allergen and a preexisting specific IgE=histamine release causes vasodilation and increase capillary permeability allowing fluid to leak into the interstitial space, vasospasm, bronchoconstriction. Get increase venous pooling, reduced arterial pressure and rapid fluid loss in interstitial spaces causing decrease venous return. o Clinical manifestations: occurs seconds to minutes after exposure, feelings of uneasiness, impending doom; flushing, urticaria and angioedema. o Therapeutic management: ventilation, restoring adequate circulation and preventing further exposure-remove antigen, fluids, oxygen, beta-agonists, antihistamines and corticosteroids. Mild with antihistamines (Benadryl or cetirizine) o Nursing care management-recognize and intervene; IVF’s, I& O, vital signs o Treatment: Early recognition, Airway patency, Adequate circulation, Prevent further exposure, Epinephrine