Nursing 316 Exam 1 – Questions With Proper
Solutions
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Practice questions for this set
Learn 1 /7 Study using Learn
1. removal of drug from the body
2. only free, unbound, hydrophilic (water soluble) drugs can be eliminated by
kidneys
Choose an answer
1 pharmacology 2 excretion
3 reason for discarded trial drug 4 effectiveness
Don't know?
Terms in this set (159)
pharmacology the study of drugs and their interactions with living
systems
drugs (medications) chemicals introduced into the body to effect
physiological processes
,drug actions 1. replacing or acting as substitute for missing
chemicals
2. increasing or stimulating cellular activities
3. depressing or slowing cellular activities
4. interfering with activities of foreign cells
(antibiotics)
"ideal" drug 1. effectiveness
2. safety
3. selectivity
effectiveness drug that does something useful. all drugs must be
effective prior to market release
safety does not produce harmful effects
relative safety of a drug increases by proper drug selection, dosage, and
monitoring
selectivity elicits only desired response and not undesired or
adverse effects
3 principles of drug action 1. drugs modify existing functions within body
2. drug has a single action
3. effects are determined by drug interaction with
body
pure food and drug act (1906) required listing of ingredients
federal food, drug, and cosmetic act (1938) test drug toxicity, ability to recall drugs, only
safe drugs receive FDA approval, gave FDA power
Harris-Kefauver amendments (1962) safety and efficacy had to be established
before marketing. FDA power over drug
investigations
, reason for discarded trial drug 1. lack of therapeutic activity
2. toxicity
3. teratogenic effects
4. not safe enough
teratogenic developmental defects in the somatic tissues of a
fetus
mutagenic changes in genetic material
FDA pregnancy category 1. A: no risk
2. B: no risk
3. C: somewhat
4. D: risk
5. X: risk
controlled substances act (1970) defined drug abuse and drugs that may be
abused. control for distribution, storage, and uses
DEA schedule of controlled I (highest abuse) > V (lowest abuse)
substances
orphan drugs not financially viable, developed for diseases with
low population.
generic drugs not protected by patent. replicated by other
companies after 7 years
over-the-counter (OTC) available without a prescription
orphan drug act (1983) facilitates developments of drugs for rare
diseases. effects fewer than 200,000 people. ex.
Huntington's, Tourettes.
Solutions
Save
Practice questions for this set
Learn 1 /7 Study using Learn
1. removal of drug from the body
2. only free, unbound, hydrophilic (water soluble) drugs can be eliminated by
kidneys
Choose an answer
1 pharmacology 2 excretion
3 reason for discarded trial drug 4 effectiveness
Don't know?
Terms in this set (159)
pharmacology the study of drugs and their interactions with living
systems
drugs (medications) chemicals introduced into the body to effect
physiological processes
,drug actions 1. replacing or acting as substitute for missing
chemicals
2. increasing or stimulating cellular activities
3. depressing or slowing cellular activities
4. interfering with activities of foreign cells
(antibiotics)
"ideal" drug 1. effectiveness
2. safety
3. selectivity
effectiveness drug that does something useful. all drugs must be
effective prior to market release
safety does not produce harmful effects
relative safety of a drug increases by proper drug selection, dosage, and
monitoring
selectivity elicits only desired response and not undesired or
adverse effects
3 principles of drug action 1. drugs modify existing functions within body
2. drug has a single action
3. effects are determined by drug interaction with
body
pure food and drug act (1906) required listing of ingredients
federal food, drug, and cosmetic act (1938) test drug toxicity, ability to recall drugs, only
safe drugs receive FDA approval, gave FDA power
Harris-Kefauver amendments (1962) safety and efficacy had to be established
before marketing. FDA power over drug
investigations
, reason for discarded trial drug 1. lack of therapeutic activity
2. toxicity
3. teratogenic effects
4. not safe enough
teratogenic developmental defects in the somatic tissues of a
fetus
mutagenic changes in genetic material
FDA pregnancy category 1. A: no risk
2. B: no risk
3. C: somewhat
4. D: risk
5. X: risk
controlled substances act (1970) defined drug abuse and drugs that may be
abused. control for distribution, storage, and uses
DEA schedule of controlled I (highest abuse) > V (lowest abuse)
substances
orphan drugs not financially viable, developed for diseases with
low population.
generic drugs not protected by patent. replicated by other
companies after 7 years
over-the-counter (OTC) available without a prescription
orphan drug act (1983) facilitates developments of drugs for rare
diseases. effects fewer than 200,000 people. ex.
Huntington's, Tourettes.
