NUR 128 COMPREHENSIVE ASSESSMENT 2026
QUESTIONS AND SOLUTIONS GRADED A+
▶ Monitor the International Normalized Ratio (INR) . Answer: when
warfarin is used
▶ dabigatran (Pradaxa) . Answer: Blood Factor IIa inhibitor (direct thrombin
inhibitor)
▶ Idarucizumab . Answer: is an antidote to dabigatran-induced hemorrhage
▶ Blood Factor Xa inhibitors . Answer: apixaban (Eliquis), edoxaban
(Savaysa), rivaroxaban (Xarelto), fondaparinux (Arixtra).
▶ Eptifibatide . Answer: binds to GPIIb/IIIa receptor sites on platelets
▶ One symptom of hemolytic anemia . Answer: is jaundice, caused by the
destruction of heme that is greater than the hepatic conjugation and
excretion of bilirubin.
▶ Jaundice . Answer: can be caused by hemolytic anemia, sickle cell
anemia, pancreatitis, cholecystitis, and multi-drug therapy used to treat
pulmonary tuberculosis
▶ Erythropoietin . Answer: is a substance manufactured in the kidney; the
anemia of chronic renal failure reduces erythropoietin production, and
should be used to correct the anemia of chronic renal failure.
▶ CNS/Neurology/Psychiatry:
Sumatriptan . Answer: is the only triptan available as an injection, as
tablets, and as a nasal spray
▶ Sumatriptan and zolmitriptan . Answer: are the only triptans available as
nasal sprays
▶ Intravenous Anesthetics . Answer: ketamine, thiopental, fentanyl,
propofol, dexmedetomidine
, ▶ Propofol . Answer: Used for sedation in ICU, rapid anesthesia induction,
short procedures. Less postoperative nausea;has a rapid onset, does not
usually cause nausea, and poor analgesia
▶ Propofol can affect . Answer: triglycerides; monitor triglyceride levels
▶ ICU delirium . Answer: a serious problem encountered in the ICU;
patients have an increased length of stay & increased mortality; commonly
occurs in elderly patients, is treated with haloperidol, although
dexmedetomidine (Precedex) is the preferred drug for sedation in the
elderly
▶ If respiratory depression is a concern . Answer: dexmedetomidine
(Precedex) is the preferred anesthetic; however, it should not be used
longer than 24 hours as per the FDA-approved product information.
▶ Selective serotonin reuptake inhibitors (SSRIs) . Answer: a group of
second-generation antidepressant drugs that increase serotonin activity
specifically, without affecting other neurotransmitters; citalopram (Celexa),
escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox),
paroxetine (Paxil), sertraline (Zoloft), vortioxetine (Trintellix).
▶ Side effects of SSRIs . Answer: include weight gain, GI distress,
decreased sexual libido and insomnia
▶ Olanzapine . Answer: Zyprexa; a second-generation antipsychotic, has
the advantage of being available as a long-acting injection for acute
psychotic reactions
▶ Drugs most effective in alcohol withdrawal . Answer: Lorazepam (Ativan)
and phenobarbital; if liver dysfunction is present, lorazepam is the preferred
agent because of its different metabolic pathway than other
benzodiazepines.
▶ All Benzodiazepines . Answer: May cause drowsiness. Alcohol may
intensify this effect. Use care when operating a car or dangerous
machinery
QUESTIONS AND SOLUTIONS GRADED A+
▶ Monitor the International Normalized Ratio (INR) . Answer: when
warfarin is used
▶ dabigatran (Pradaxa) . Answer: Blood Factor IIa inhibitor (direct thrombin
inhibitor)
▶ Idarucizumab . Answer: is an antidote to dabigatran-induced hemorrhage
▶ Blood Factor Xa inhibitors . Answer: apixaban (Eliquis), edoxaban
(Savaysa), rivaroxaban (Xarelto), fondaparinux (Arixtra).
▶ Eptifibatide . Answer: binds to GPIIb/IIIa receptor sites on platelets
▶ One symptom of hemolytic anemia . Answer: is jaundice, caused by the
destruction of heme that is greater than the hepatic conjugation and
excretion of bilirubin.
▶ Jaundice . Answer: can be caused by hemolytic anemia, sickle cell
anemia, pancreatitis, cholecystitis, and multi-drug therapy used to treat
pulmonary tuberculosis
▶ Erythropoietin . Answer: is a substance manufactured in the kidney; the
anemia of chronic renal failure reduces erythropoietin production, and
should be used to correct the anemia of chronic renal failure.
▶ CNS/Neurology/Psychiatry:
Sumatriptan . Answer: is the only triptan available as an injection, as
tablets, and as a nasal spray
▶ Sumatriptan and zolmitriptan . Answer: are the only triptans available as
nasal sprays
▶ Intravenous Anesthetics . Answer: ketamine, thiopental, fentanyl,
propofol, dexmedetomidine
, ▶ Propofol . Answer: Used for sedation in ICU, rapid anesthesia induction,
short procedures. Less postoperative nausea;has a rapid onset, does not
usually cause nausea, and poor analgesia
▶ Propofol can affect . Answer: triglycerides; monitor triglyceride levels
▶ ICU delirium . Answer: a serious problem encountered in the ICU;
patients have an increased length of stay & increased mortality; commonly
occurs in elderly patients, is treated with haloperidol, although
dexmedetomidine (Precedex) is the preferred drug for sedation in the
elderly
▶ If respiratory depression is a concern . Answer: dexmedetomidine
(Precedex) is the preferred anesthetic; however, it should not be used
longer than 24 hours as per the FDA-approved product information.
▶ Selective serotonin reuptake inhibitors (SSRIs) . Answer: a group of
second-generation antidepressant drugs that increase serotonin activity
specifically, without affecting other neurotransmitters; citalopram (Celexa),
escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox),
paroxetine (Paxil), sertraline (Zoloft), vortioxetine (Trintellix).
▶ Side effects of SSRIs . Answer: include weight gain, GI distress,
decreased sexual libido and insomnia
▶ Olanzapine . Answer: Zyprexa; a second-generation antipsychotic, has
the advantage of being available as a long-acting injection for acute
psychotic reactions
▶ Drugs most effective in alcohol withdrawal . Answer: Lorazepam (Ativan)
and phenobarbital; if liver dysfunction is present, lorazepam is the preferred
agent because of its different metabolic pathway than other
benzodiazepines.
▶ All Benzodiazepines . Answer: May cause drowsiness. Alcohol may
intensify this effect. Use care when operating a car or dangerous
machinery
