NUR 651 FINAL BRADLEY UNIVERSITY
EXAM ACTUAL QUESTIONS ACTUAL
PAPER 2026 COMPLETE QUESTIONS AND
ANSWERS GRADED A+
⩥ Following genetic testing, it was discovered that J.T. can metabolize
warfarin perfectly through his liver as all his CYP enzymes came back
normal (no mutations). Which of the following options could thus
explain his excessive bleeding? Answer: J. T. is A haplotype for
VKORC1.
⩥ How should Warfarin dose be adjusted for Haplotype VKORC1
Answer: Lower dose should be given
⩥ Why is it important for the clinician studying pharmacogenomics to
understand the concept of SNPs and differing alleles? Answer: SNPs
have different alleles on the same gene producing different metabolic
effects.
⩥ What is the mechanism of action of warfarin? Answer: Inhibits
vitamin K epoxide reductase, an enzyme needed for clotting factor
synthesis
, ⩥ A patient mutation of CYP2C19 is documented as (*1/*17,*17/*17).
What is the term for a person with this function mutation? Answer:
Ultrarapid metabolizer
⩥ Which is the correct anticoagulant antidote combination? Answer:
Dabigatran (Pradaxa®): inactivated coagulation factor Xa
⩥ Warfarin is a mixture of two enantiomers. What is an enantiomer?
Answer: One of two stereoisomers that are mirror images of each other
⩥ What is a narrow therapeutic window? Answer: A drug that has little
difference between therapeutic and toxic doses
⩥ A practitioner is prescribing amiodarone for a patient with cardiac
arrhythmia. Which factor affecting the duration of the drug must a
practitioner consider if an adverse interaction occurs? Answer: Half-life
⩥ A practitioner prescribes a bicarbonate for a patient with severe
heartburn. The practitioner knows that what factor caused by the drug
plays a key role in its excretion? Answer: Alkalinization of the urine
⩥ A health care practitioner prescribes warfarin for a patient who has
AFib. The patient should avoid foods high in... Answer: Vitamin K
EXAM ACTUAL QUESTIONS ACTUAL
PAPER 2026 COMPLETE QUESTIONS AND
ANSWERS GRADED A+
⩥ Following genetic testing, it was discovered that J.T. can metabolize
warfarin perfectly through his liver as all his CYP enzymes came back
normal (no mutations). Which of the following options could thus
explain his excessive bleeding? Answer: J. T. is A haplotype for
VKORC1.
⩥ How should Warfarin dose be adjusted for Haplotype VKORC1
Answer: Lower dose should be given
⩥ Why is it important for the clinician studying pharmacogenomics to
understand the concept of SNPs and differing alleles? Answer: SNPs
have different alleles on the same gene producing different metabolic
effects.
⩥ What is the mechanism of action of warfarin? Answer: Inhibits
vitamin K epoxide reductase, an enzyme needed for clotting factor
synthesis
, ⩥ A patient mutation of CYP2C19 is documented as (*1/*17,*17/*17).
What is the term for a person with this function mutation? Answer:
Ultrarapid metabolizer
⩥ Which is the correct anticoagulant antidote combination? Answer:
Dabigatran (Pradaxa®): inactivated coagulation factor Xa
⩥ Warfarin is a mixture of two enantiomers. What is an enantiomer?
Answer: One of two stereoisomers that are mirror images of each other
⩥ What is a narrow therapeutic window? Answer: A drug that has little
difference between therapeutic and toxic doses
⩥ A practitioner is prescribing amiodarone for a patient with cardiac
arrhythmia. Which factor affecting the duration of the drug must a
practitioner consider if an adverse interaction occurs? Answer: Half-life
⩥ A practitioner prescribes a bicarbonate for a patient with severe
heartburn. The practitioner knows that what factor caused by the drug
plays a key role in its excretion? Answer: Alkalinization of the urine
⩥ A health care practitioner prescribes warfarin for a patient who has
AFib. The patient should avoid foods high in... Answer: Vitamin K
