UNIT 3 Pharmacology and Pathophysiology: Antineoplastics Mechanisms, Cell-Cycle Specificity, Chemotherapy Toxicities, Nausea Control, Immunomodulation, Monoclonal Antibodies, Transplant Immunosuppression, Hematopoietic Colony Stimulation, Infectious Disea

UNIT 3 Pharmacology and Pathophysiology: Antineoplastics Mechanisms, Cell-Cycle Specificity, Chemotherapy Toxicities, Nausea Control, Immunomodulation, Monoclonal Antibodies, Transplant Immunosuppression, Hematopoietic Colony Stimulation, Infectious Disease Management, Antibiotic Spectrum and Mechanisms, Resistance and Superinfections, Beta-Lactam Therapy, Aminoglycosides and Ototoxicity, Tetracyclines and Photosensitivity, Macrolide and Fluoroquinolone Targets, Sulfonamides and Crystalluria, Vancomycin and MRSA, Antifungal Therapy, Candida and Dermatophytes, Amphotericin Toxicity, Systemic and Local Mycoses, Antimalarial DNA Inhibition, CNS Adverse Effects, Anthelmintic Neuromuscular Paralysis, Antiviral Static Mechanisms, Antiretroviral DNA Analogs, Antitubercular Hepatotoxicity, Rifampin Staining, AIDS-Defining Infections, Vaccines and Immunity Types, and Supportive Pharmacologic Interventions Exam Questions Verified and Provided with Complete A+ Graded Rationales Latest Updated 2026 Malaria symptoms sweating, high fever, chills, jaundice, anemia 2 classes of cell cycle specific antineoplastics antimetabolites & mitotic inhibitors (plant alkaloids) alopecia means hair loss All of the following drug classes treat cancer except: Mitotic Inhibitors, tetracycline, alkylating agents, cytotoxic antibiotics tetracycline 3 multiple choice options class of meds for nausea & vomitting antiemetics Which of the following antineoplastics are cell cycle specific? antimetabolites 3 multiple choice options Alkylating agents interfere with aspects of the nucleic acid metabolism of rapidly growing tumor cells. true or false true 2 multiple choice options Benign tumors are slow growing, do not metastasize, and rarely require drug treatment. True or False true 2 multiple choice options A tumor of the fat cells would be an example of a sarcoma type of cancer related to connective or other non-epithelial tissue sarcomas (bone, muscle, fat, leukocyte, lymphocytes) type of cancer in epithelial layer of skin or lining of internal organs carcinomas leading type of cancer death in US in men & women lung list the 2 Cell cycle non-specific classes of antineoplastics alkylating agents & cytotoxic antibiotics MOA of alkylating agents change structure of DNA inhibiting cell division most frequently used alkylating agent drug cyclophosphamide (Cytoxan) MOA of antimetabolites inhibit DNA synthesis MOA of cytotoxic antibiotics change structure of DNA inhibiting cell division MOA of mitotic inhibitors (plant alkaloids) disrupt mitotic spindles MOA of monoclonal antibodies selectively bind & inhibit cell antigens or receptors