Lehne’s Pharmacotherapeutics
CERTIFICATION PAPER 2026 FULL
SOLUTION GRADED A+
● Some foods can inhibit CYP isoenzymes and alter drug metabolism.
Answer: Which statement about food and drug interactions is true?
● Ask the patient about over-the-counter medications used.
Contact the prescriber to request cytochrome P450 levels.
Obtain a thorough diet history. Answer: A nurse is caring for a patient
who is taking multiple medications. To help ensure that adverse drug
reactions are prevented or minimized, the nurse will do which of the
following?
● An increased adverse effect Answer: A patient is taking two
prescription medications that both adversely cause bradycardia. The
nurse should monitor the patient for which type of effect?
● An adult who takes eight prescription medications for a chronic
condition Answer: Which individual is at the highest risk for a drug-drug
interaction?
● " I drink a glass of grapefruit juice each evening." Answer: The nurse
cares for a patient who is taking a calcium channel blocker for
, hypertension. The nurse should be most concerned if the patient makes
which statement?
● "Take the medication 1 hour before eating." Answer: A patient is
prescribed a medication to be taken on an empty stomach. Which
statement should the nurse include when providing patient teaching?
● whenever a patient takes two or more drugs Answer: Drug-drug
interactions can occur....
● -one drug may intensify the effects of the other
-one drug may reduce the effects of the other
-the combination may produce a new response not seen with either drug
alone Answer: What are 3 possible outcomes when drugs interact?
● inhibitory drugs Answer: interactions that result in reduced drug
effects
● -direct chemical or physical interaction
-pharmacokinetic interaction
-pharmacodynamic interaction
-combined toxicity Answer: Drugs interact through four basic
mechanisms:
CERTIFICATION PAPER 2026 FULL
SOLUTION GRADED A+
● Some foods can inhibit CYP isoenzymes and alter drug metabolism.
Answer: Which statement about food and drug interactions is true?
● Ask the patient about over-the-counter medications used.
Contact the prescriber to request cytochrome P450 levels.
Obtain a thorough diet history. Answer: A nurse is caring for a patient
who is taking multiple medications. To help ensure that adverse drug
reactions are prevented or minimized, the nurse will do which of the
following?
● An increased adverse effect Answer: A patient is taking two
prescription medications that both adversely cause bradycardia. The
nurse should monitor the patient for which type of effect?
● An adult who takes eight prescription medications for a chronic
condition Answer: Which individual is at the highest risk for a drug-drug
interaction?
● " I drink a glass of grapefruit juice each evening." Answer: The nurse
cares for a patient who is taking a calcium channel blocker for
, hypertension. The nurse should be most concerned if the patient makes
which statement?
● "Take the medication 1 hour before eating." Answer: A patient is
prescribed a medication to be taken on an empty stomach. Which
statement should the nurse include when providing patient teaching?
● whenever a patient takes two or more drugs Answer: Drug-drug
interactions can occur....
● -one drug may intensify the effects of the other
-one drug may reduce the effects of the other
-the combination may produce a new response not seen with either drug
alone Answer: What are 3 possible outcomes when drugs interact?
● inhibitory drugs Answer: interactions that result in reduced drug
effects
● -direct chemical or physical interaction
-pharmacokinetic interaction
-pharmacodynamic interaction
-combined toxicity Answer: Drugs interact through four basic
mechanisms:
