(Primary Immunodeficiency)
2026 Exam Questions and
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What is the cause of PI? - 🧠 ANSWER ✔✔Intrinsic defect in the immune
system
,Immune system is the primary cause
Usually related to genetic defects
What are sx of PI? - 🧠 ANSWER ✔✔recurrent infections
left untreated can result in organ damage
o The World Health Organization recognizes over 350 PI diseases
.
o Some are common, while others are quite rare.
o Some affect a single cell, and others affect two or more components.
o Commonly have increased susceptibility to infection and often develop
serious and debilitating illnesses.
, o PI diseases can occur in individuals of any age.
o The time from symptom onset to proper diagnosis often takes years.
o It is estimated that 1 in every 1,200 - 2,000 people may have some form
of PI disease.
o There is a strong link between PI disease and autoimmune disorders.
o Effective therapy exists for many of the PI diseases, and many people
with these disorders can live relatively normal lives.
Which Ig products are approved for PI? - 🧠 ANSWER ✔✔All but one
What is secondary immunodeficiency? - 🧠 ANSWER ✔✔Result of damage
to the immune system caused by a disease, a consequence of certain
medications, or exposure to toxins or radiation
Examples:
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