NURS 236 Pharmacology and Pathophysiology Examination: Nausea & Vomiting
Mechanisms, Antiemetic Drug Classes, Serotonin-Dopamine-Histamine-
Acetylcholine Pathways, Chemotherapy-Induced and Motion Sickness Nausea,
Beta-2 Adrenergic Agonists, Anticholinergic Bronchodilators, Corticosteroid Anti-
Inflammatory Therapy, Mucolytics and Expectorants, Hypertension
Pathophysiology, ACE Inhibitors, ARBs, Calcium Channel and Beta-Adrenergic
Blockers, Heart Failure Management, Digoxin Therapeutic Monitoring,
Sympathomimetic and Alpha/Beta Adrenergic Modulation, Postpartum and
Newborn Assessment, TORCH Infections, Polyhydramnios, Fetal Monitoring,
Pharmacologic Nursing Considerations, and High-Risk Patient Safety Exam
Questions Verified and Provided with Complete A+ Graded Rationales Latest
Updated 2026
What is the primary function of the vomiting center?
It controls the vomiting reflex.
Which neurotransmitter is most involved in chemotherapy-induced nausea?
Serotonin
What are the indications for Ondansetron?
Chemotherapy-induced nausea, post-operative nausea, gastroenteritis.
What is a common adverse effect of Ondansetron?
,Headache
What should be monitored in high-risk patients taking Ondansetron?
ECG
What class of drug is Prochlorperazine (Compazine)?
Dopamine (D2) antagonist
What unique action does Metoclopramide (Reglan) have?
Increases gastric emptying and LES tone.
What is a black box warning associated with Metoclopramide?
Tardive dyskinesia with long-term use.
Which antiemetic is effective for motion sickness?
Meclizine or Dimenhydrinate
What class of drug is Scopolamine?
Antimuscarinic
, What is a common side effect of Scopolamine?
Dry mouth
What route is Scopolamine administered?
Transdermal patch (behind ear)
What condition should caution the use of Scopolamine?
Glaucoma
What is the mechanism of action for serotonin antagonists?
They block serotonin in the GI tract and CTZ.
What is the primary indication for dopamine antagonists?
Severe nausea/vomiting.
Which antiemetic improves gastric motility?
Metoclopramide
What is the role of the CTZ in nausea and vomiting?
Mechanisms, Antiemetic Drug Classes, Serotonin-Dopamine-Histamine-
Acetylcholine Pathways, Chemotherapy-Induced and Motion Sickness Nausea,
Beta-2 Adrenergic Agonists, Anticholinergic Bronchodilators, Corticosteroid Anti-
Inflammatory Therapy, Mucolytics and Expectorants, Hypertension
Pathophysiology, ACE Inhibitors, ARBs, Calcium Channel and Beta-Adrenergic
Blockers, Heart Failure Management, Digoxin Therapeutic Monitoring,
Sympathomimetic and Alpha/Beta Adrenergic Modulation, Postpartum and
Newborn Assessment, TORCH Infections, Polyhydramnios, Fetal Monitoring,
Pharmacologic Nursing Considerations, and High-Risk Patient Safety Exam
Questions Verified and Provided with Complete A+ Graded Rationales Latest
Updated 2026
What is the primary function of the vomiting center?
It controls the vomiting reflex.
Which neurotransmitter is most involved in chemotherapy-induced nausea?
Serotonin
What are the indications for Ondansetron?
Chemotherapy-induced nausea, post-operative nausea, gastroenteritis.
What is a common adverse effect of Ondansetron?
,Headache
What should be monitored in high-risk patients taking Ondansetron?
ECG
What class of drug is Prochlorperazine (Compazine)?
Dopamine (D2) antagonist
What unique action does Metoclopramide (Reglan) have?
Increases gastric emptying and LES tone.
What is a black box warning associated with Metoclopramide?
Tardive dyskinesia with long-term use.
Which antiemetic is effective for motion sickness?
Meclizine or Dimenhydrinate
What class of drug is Scopolamine?
Antimuscarinic
, What is a common side effect of Scopolamine?
Dry mouth
What route is Scopolamine administered?
Transdermal patch (behind ear)
What condition should caution the use of Scopolamine?
Glaucoma
What is the mechanism of action for serotonin antagonists?
They block serotonin in the GI tract and CTZ.
What is the primary indication for dopamine antagonists?
Severe nausea/vomiting.
Which antiemetic improves gastric motility?
Metoclopramide
What is the role of the CTZ in nausea and vomiting?
