NBME Assessments Questions with Verified Correct Answers 2026/2027 Latest Updated Study Guide

Master the NBME assessments with this comprehensive study guide featuring actual exam questions and verified correct answers for 2026/2027. Covering all essential medical topics including obstetrics and gynecology (early decelerations head compression, variable decelerations cord compression, late decelerations uteroplacental insufficiency, abruptio placentae painful bleeding third trimester, placenta previa, preeclampsia diagnosis beta-adrenergic blocking agents, eclampsia, gestational diabetes cephalopelvic disproportion, Group B strep prophylaxis, ruptured membranes at 28 weeks corticosteroids, uterine inversion, postpartum endometritis ampicillin gentamicin, ovarian mass testosterone secreting tumor hirsutism, simple ovarian cyst oral contraceptive therapy, polycystic ovary syndrome PCOS increased 5-alpha reductase activity DHT, ovarian torsion RLQ pain cystic and solid mass, ovarian cyst torsion, ovarian cancer, vulvar carcinoma labium majus ulcerated lesion biopsy, vulvar itching, cervical cancer squamous cell carcinoma HPV, PAP smear frequency in immunocompromised, endometrial cancer obesity androstenedione to estrogen conversion, uterine anomalies congenital bicornuate uterus preterm labor, hematocolpos imperforate hymen, primary dysmenorrhea prostaglandins, endometriosis diagnosis laparoscopy, infertility hysterosalpingography, Turner syndrome elevated FSH LH, Kallmann syndrome hypogonadotropic hypogonadism anosmia, androgen insensitivity syndrome 46 XY complete androgen resistance, 5-alpha reductase deficiency 46 XY ambiguous genitalia, maternal-fetal medicine parvovirus B19 fetal hydrops, valproic acid neural tube defects), internal medicine (sarcoidosis hilar adenopathy noncaseating granulomas, amyotrophic lateral sclerosis ALS upper and lower motor neuron signs, myasthenia gravis, multiple sclerosis, Paget disease of bone increased alkaline phosphatase bone scan uptake, osteoporosis, osteoarthritis Heberden nodes, rheumatoid arthritis Felty syndrome splenomegaly neutropenia, gout acute indomethacin, pseudogout, calcium pyrophosphate deposition disease, septic arthritis joint aspiration, cellulitis, dermatitis, psoriasis, zinc deficiency alopecia hyperkeratotic lesions, diabetes mellitus type 1 DKA dextrose administration, diabetes mellitus type 2 ACE inhibitor enalapril nephropathy prevention, diabetic complications, hypoglycemia, hyperglycemia, diabetic ketoacidosis, hyperosmolar hyperglycemic state, metabolic syndrome, obesity BMI 52 knee pain weight loss intervention, hypertension mineralocorticoid excess hypokalemic alkalosis, hypertensive emergency, hyperaldosteronism, pheochromocytoma, renovascular hypertension, atherosclerosis, coronary artery disease, myocardial infarction, angina pectoris variant Prinzmetal angina ST elevation, unstable angina, heart failure dilated cardiomyopathy biventricular enlargement, congestive heart failure pleural fluid glucose serum glucose, cor pulmonale, pericardial effusion paradoxical pulse, pericarditis, aortic stenosis bicuspid aortic valve systolic ejection murmur, aortic regurgitation diastolic murmur, mitral valve prolapse midsystolic click, infective endocarditis, pulmonary embolism recurrent dyspnea V/Q mismatch, deep vein thrombosis, fat embolism syndrome long bone fracture petechiae altered mentation, rhabdomyolysis acute kidney injury elevated CK, acute renal failure amikacin toxicity muddy brown casts, chronic kidney disease uremia anorexia elevated creatinine, polycystic kidney disease AD inheritance 50% risk, nephrotic syndrome, glomerulonephritis, pyelonephritis costovertebral angle tenderness WBC casts, urinary tract infection UTI prophylaxis trimethoprim-sulfamethoxazole, urolithiasis, stress incontinence decreased urethral sphincter tone, urge incontinence oxybutynin, urinary retention, benign prostatic hyperplasia, prostate cancer, prostatitis ciprofloxacin, epididymitis, testicular torsion, hydrocele, varicocele, erectile dysfunction, hypogonadism, gynecomastia, Klinefelter syndrome 47 XXY small testes elevated FSH LH, cirrhosis, hepatitis acute elevated AST ALT, alcoholic liver disease, nonalcoholic fatty liver disease, Gilbert syndrome unconjugated hyperbilirubinemia, hemochromatosis serum ferritin elevated, Wilson disease, alpha-1 antitrypsin deficiency emphysema, pancreatitis hyperamylasemia hypocalcemia, cholecystitis, cholelithiasis, cholangitis, diverticulitis perforated sigmoid colectomy, inflammatory bowel disease Crohn disease ulcerative colitis, celiac disease endomysial IgA antibody gluten-sensitive enteropathy, irritable bowel syndrome, peptic ulcer disease, gastroesophageal reflux disease GERD H2 receptor blocker, achalasia barium swallow bird-beak, esophageal cancer, gastric cancer, colorectal cancer colonoscopy screening, pancreatic cancer, hepatocellular carcinoma, cholangiocarcinoma, lung cancer adenocarcinoma peripheral lesion nonsmoker, small cell lung cancer, non-small cell lung cancer, mesothelioma, pneumonia community-acquired, hospital-acquired pneumonia, aspiration pneumonia clindamycin foul-smelling sputum, tuberculosis PPD positive isoniazid treatment, latent TB, active TB, nontuberculous mycobacteria, bronchiectasis, chronic obstructive pulmonary disease COPD ipratropium bromide, asthma intrinsic non-atopic, exercise-induced bronchoconstriction, allergic bronchopulmonary aspergillosis, sarcoidosis noncaseating granulomas, idiopathic pulmonary fibrosis, hypersensitivity pneumonitis, occupational lung disease coal workers pneumoconiosis, pulmonary Langerhans cell histiocytosis, lymphangioleiomyomatosis, pleural effusion, empyema, pneumothorax, hemothorax, chylothorax, sleep apnea, obesity hypoventilation syndrome, altitude sickness, decompression sickness, toxicology organophosphate poisoning cholinesterase inhibitor pinpoint pupils bradycardia, heavy metal poisoning, acetaminophen toxicity, salicylate toxicity, carbon monoxide poisoning, cyanide toxicity, ethanol intoxication, methanol poisoning, ethylene glycol toxicity, opioid overdose naloxone, benzodiazepine overdose flumazenil, tricyclic antidepressant overdose, lithium toxicity, digoxin toxicity, theophylline toxicity, local anesthetic toxicity intravascular injection tinnitus metallic taste, snake envenomation, spider bites, marine envenomation, food poisoning, botulism, tetanus, diphtheria, pertussis, Haemophilus ducreyi chancroid painful ulcer, Treponema pallidum syphilis FTA-ABS confirmatory, Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis flagellated protozoa metronidazole, Gardnerella vaginalis bacterial vaginosis, Candida albicans vulvovaginitis refractory diabetes, herpes simplex virus HSV acyclovir oral, varicella-zoster virus VZV shingles IV acyclovir immunocompromised, cytomegalovirus CMV, Epstein-Barr virus EBV, human papillomavirus HPV condylomata acuminata, molluscum contagiosum, scabies, pediculosis pubis, Lyme disease Borrelia burgdorferi, Rocky Mountain spotted fever, ehrlichiosis, anaplasmosis, babesiosis, tularemia, brucellosis, leptospirosis, rat-bite fever, cat-scratch disease, Q fever, typhoid fever, cholera, shigellosis, salmonellosis, campylobacteriosis, Escherichia coli O157:H7, Clostridium difficile colitis, Clostridium perfringens gas gangrene, Clostridium botulinum botulism, Clostridium tetani tetanus, Bacillus anthracis anthrax, Yersinia pestis plague, Francisella tularensis tularemia, Burkholderia mallei glanders, Burkholderia pseudomallei melioidosis, Bartonella henselae cat-scratch disease, Coxiella burnetii Q fever, Rickettsia rickettsii Rocky Mountain spotted fever, Rickettsia prowazekii epidemic typhus, Rickettsia typhi murine typhus, Orientia tsutsugamushi scrub typhus, Ehrlichia chaffeensis human monocytic ehrlichiosis, Anaplasma phagocytophilum human granulocytic anaplasmosis, Borrelia recurrentis relapsing fever, Borrelia burgdorferi Lyme disease, Treponema pallidum syphilis, Leptospira interrogans leptospirosis, Mycobacterium tuberculosis, Mycobacterium leprae leprosy, Mycobacterium avium complex, Nocardia asteroides nocardiosis, Actinomyces israelii actinomycosis, fungal infections histoplasmosis, coccidioidomycosis, blastomycosis, paracoccidioidomycosis, sporotrichosis, cryptococcosis, candidiasis, aspergillosis, mucormycosis, pneumocystis jirovecii pneumonia, parasitic infections malaria, toxoplasmosis, cryptosporidiosis, cyclosporiasis, isosporiasis, giardiasis, amebiasis, leishmaniasis, trypanosomiasis, schistosomiasis, strongyloidiasis, ascariasis, hookworm, trichuriasis, enterobiasis, taeniasis, cysticercosis, echinococcosis, filariasis, onchocerciasis, loiasis, dracunculiasis, lymphatic filariasis, scabies, pediculosis, demodicosis, tungiasis, myiasis, hematology iron deficiency anemia decreased MCV, thalassemia hemoglobin electrophoresis, megaloblastic anemia B12 folate, pernicious anemia, hemolytic anemia, sickle cell disease, glucose-6-phosphate dehydrogenase deficiency G6PD, hereditary spherocytosis, autoimmune hemolytic anemia, paroxysmal nocturnal hemoglobinuria, aplastic anemia, pure red cell aplasia, sideroblastic anemia, anemia of chronic disease, polycythemia vera, essential thrombocythemia, primary myelofibrosis, chronic myeloid leukemia CML metamyelocytes Philadelphia chromosome, acute myeloid leukemia AML, acute lymphoblastic leukemia ALL, chronic lymphocytic leukemia CLL, Hodgkin lymphoma Reed-Sternberg cells, non-Hodgkin lymphoma, multiple myeloma, Waldenström macroglobulinemia, monoclonal gammopathy of undetermined significance MGUS, amyloidosis, hemophilia A factor VIII deficiency, hemophilia B factor IX deficiency, von Willebrand disease, disseminated intravascular coagulation DIC, thrombotic thrombocytopenic purpura TTP, hemolytic uremic syndrome HUS, immune thrombocytopenic purpura ITP, heparin-induced thrombocytopenia HIT, vitamin K deficiency warfarin, coagulation cascade, INR, PT, PTT, bleeding disorders, thrombosis, antiphospholipid syndrome, factor V Leiden, protein C deficiency, protein S deficiency, antithrombin deficiency, prothrombin gene mutation, hyperhomocysteinemia, oncology cancer screening, tumor markers, carcinogenesis, oncogenes, tumor suppressor genes p53 RB, paraneoplastic syndromes, chemotherapy adverse effects, radiation therapy, targeted therapy, immunotherapy, stem cell transplant, palliative care, hospice, end-of-life care, pain management, opioid analgesics, NSAIDs, acetaminophen, adjuvant analgesics, neuropathic pain gabapentin, breakthrough pain, patient-controlled analgesia PCA, WHO analgesic ladder, nerve blocks, epidural analgesia, palliative sedation, advance directives, living will, durable power of attorney for healthcare, do not resuscitate DNR orders, physician orders for life-sustaining treatment POLST, ethics informed consent, medical futility, withholding and withdrawing treatment, euthanasia, physician-assisted suicide, hospice eligibility, Medicare hospice benefit, bereavement, grief, complicated grief, anticipatory grief, disenfranchised grief, mourning, thanatology, death and dying Kübler-Ross model denial anger bargaining depression acceptance). Perfect for medical students, NBME exam preparation, USMLE Step 1, Step 2 CK, and clinical rotations.