Questions with All Actual Answers
2025-2026 Updated.
Brain region where positive symptoms occur - Answer mesolimbic
Brain region where negative symptoms occur - Answer mesocortical/nucleus acumen's
Brain region where affective symptoms occur - Answer ventromedial prefrontal cortex
Brain region where aggressive symptoms occur - Answer orbitofrontal cortex/amygdala
Brain region where cognitive symptoms occur - Answer Dorsolateral prefrontal
limbic system - Answer frontal lobe, hippocampus, parahippocampus
Hallucinations result due to - Answer overreaction in temporal lobe
what neurotransmitter is affected in schizophrenia - Answer too much dopamine; excessive
dopamine release in patients with schizophrenia has been linked to the severity of positive
psychotic symptoms.
Capgras syndrome - Answer The delusional belief that an acquaintance has been replaced by
an identical-looking imposter. It is more commonly seen in schizophrenia, dementia, and brain
trauma.
Erotomania - Answer Delusional belief, more common in women than men, that someone is
deeply in love with them, generally a person of hight status (delusions of love)
delusions of grandeur - Answer A false belief that one is a famous person or a powerful or
important person who has some great knowledge, ability, or authority. Ex. person thinks he or
she is the president or Jesus Christ
delusions of reference - Answer Delusions of reference: belief that common elements in the
environment are directed toward the individual
, Persecutory type - Answer delusions of persecution involve belief that you are being
conspired against, cheated, spied on, followed, poisoned, maligned, or harassed
somatic delusions - Answer preoccupations regarding health and organ function
Diagnostic criteria for Schizoaffective disorder - Answer Concurrent mood episode & active-
phase symptoms of schizophrenia + >2 week lifetime history of delusions/hallucinations w/o
mood disorder
unlike MDD, diminished interest or pleasure is NOT a qualifying criteria
diagnostic criteria for schizophreniform - Answer symptoms of schizophrenia are present for
more than a month but <6 months. 2/3 will progress into schizophrenia
Diagnostic Criteria for Schizophrenia - Answer Two (or more) of the following, each present
for a significant portion of time during a 1-month period.
Delusions
Hallucinations
Disorganised speech & behaviour
Negative symptoms
Neuroleptic Malignant Syndrome - Answer Adverse reaction to antipsychotics with severe
"lead pipe" rigidty, FEVER, tachycardia, increased blood pressure and mental status changes
What happens if patient is on a LAI and develops NMS? - Answer Can only give supportive
care, once that happens do not give another LAI
treatment for neuroleptic malignant syndrome - Answer discontinue medications,
dantrolene, D2 agonists (bromocryptine)
Akathisia - Answer restlessness, inability to sit still , jittery, pacing
Labs in neuroleptic malignant syndrome - Answer
Black box warning for all antipsychotics - Answer Increased risk of death in elderly patients
with dementia
Indication for long-acting injections - Answer medication non-adherence