Walden 6630 Psychopharmacology Midterm Study Guide
Study online at https://quizlet.com/_986h43
1. Serotonin regulates Mood, emotion, feeding, and repro-
ductive behavior
2. This class of antidepressants binds to presy- SSRIs
naptic SERT and inhibits them from reuptake
of serotonin to increase levels in the synaptic
cleft to bind with postsysnaptic 5HT2 recep-
tors
3. First line therapy for MDD due to milder side SSRIs
effect profiles
4. Six Common SSRIs citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
5. Onset of therapeutic benefit from SSRIs 4-6 weeks
6. In addition to MDD, SSRIs also treat Chronic Anxiety, PTSD, OCD, and eating
disorders (bulimia)
7. Five Common side effects of SSRIs include Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH
8. Severe side effect of SSRIs in children/adoles- suicidal ideation
cents under age 25 years old
9. Life threatening adverse effect of SSRIs, es- Serotonin Syndrome
pecially when used in combination with other
serotonergic drugs (SNRIs, TCAs, MAOIs, etc.)
10. Excess accumulation of serotonin resulting in Serotonin Syndrome
overstimulation of the nervous system
11. Seven symptoms of Serotonin Syndrome
, Walden 6630 Psychopharmacology Midterm Study Guide
Study online at https://quizlet.com/_986h43
Flushing, hyperthermia, agitation, mus-
cle rigidity, seizure, coma, HYPERreflexia
12. The treatment for serotonin syndrome Cyproheptadine (5-HT2 receptor an-
tagonist)
13. Cyproheptadine treats serotonin syndrome blocking 5-HT2 receptors (serotonin
by antagonist)
14. When SSRIs or SNRIs are stopped abruptly, Irritability, headaches, and insomnia
common symptoms of withdrawal include
15. Medicine specific side effect of citalopram Prolonged QT interval (nor-
mal=0.4.-0.44 seconds)
16. This SSRI is pregnancy category D due to as- Paroxetine
sociations with congenital heart defects
17. All SSRIs but paroxetine (D) are pregnancy C
category
18. Three SSRIs that are inhibitors of Cytochrome fluoxetine, fluvoxamine, and paroxetine
P450 enzymes
19. Five common SNRIs include duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
20. This antidepressant class of medications SNRIs
works by binding to presynaptic SERT and
NET to inhibit them from reuptake of sero-
tonin and norepinephrine to increase their
levels in the synaptic cleft
21. In addition to MDD SNRIs treat
, Walden 6630 Psychopharmacology Midterm Study Guide
Study online at https://quizlet.com/_986h43
Anxiety and neuropathic pain (periph-
eral neuropathy)
22. Medication specific indications of duloxetine: urinary incontinence and Fibromyalgia
23. Medication specific indications of venlafax- social anxiety, panic disorders, PTSD,
ine: OCD, postmenopausal hot flashes
24. Six common side effects of SNRIs include: Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
25. Severe side effect of SNRIs in children/adoles- suicidal ideation
cents under age 25 years old:
26. Life threatening adverse effect of SNRIs, es- Serotonin Syndrome
pecially when used in combination with other
serotonergic drugs:
27. This SNRI is an inhibitor of Cytochrome P450 venlafaxine
enzymes:
28. This SNRI is hepatotoxic: duloxetine
29. MAOIs increase the levels of: Serotonin, Norepinephrine, and
Dopamine
30. Norepinephrine regulates: alertness and focus
31. Dopamine regulates: cognitive function, motivation, and
awakeness
32. In the synaptic cleft, Monoamine Oxidase A Serotonin, Norepinephrine, and
breaks down: Dopamine
33. Dopamine
Study online at https://quizlet.com/_986h43
1. Serotonin regulates Mood, emotion, feeding, and repro-
ductive behavior
2. This class of antidepressants binds to presy- SSRIs
naptic SERT and inhibits them from reuptake
of serotonin to increase levels in the synaptic
cleft to bind with postsysnaptic 5HT2 recep-
tors
3. First line therapy for MDD due to milder side SSRIs
effect profiles
4. Six Common SSRIs citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
5. Onset of therapeutic benefit from SSRIs 4-6 weeks
6. In addition to MDD, SSRIs also treat Chronic Anxiety, PTSD, OCD, and eating
disorders (bulimia)
7. Five Common side effects of SSRIs include Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH
8. Severe side effect of SSRIs in children/adoles- suicidal ideation
cents under age 25 years old
9. Life threatening adverse effect of SSRIs, es- Serotonin Syndrome
pecially when used in combination with other
serotonergic drugs (SNRIs, TCAs, MAOIs, etc.)
10. Excess accumulation of serotonin resulting in Serotonin Syndrome
overstimulation of the nervous system
11. Seven symptoms of Serotonin Syndrome
, Walden 6630 Psychopharmacology Midterm Study Guide
Study online at https://quizlet.com/_986h43
Flushing, hyperthermia, agitation, mus-
cle rigidity, seizure, coma, HYPERreflexia
12. The treatment for serotonin syndrome Cyproheptadine (5-HT2 receptor an-
tagonist)
13. Cyproheptadine treats serotonin syndrome blocking 5-HT2 receptors (serotonin
by antagonist)
14. When SSRIs or SNRIs are stopped abruptly, Irritability, headaches, and insomnia
common symptoms of withdrawal include
15. Medicine specific side effect of citalopram Prolonged QT interval (nor-
mal=0.4.-0.44 seconds)
16. This SSRI is pregnancy category D due to as- Paroxetine
sociations with congenital heart defects
17. All SSRIs but paroxetine (D) are pregnancy C
category
18. Three SSRIs that are inhibitors of Cytochrome fluoxetine, fluvoxamine, and paroxetine
P450 enzymes
19. Five common SNRIs include duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
20. This antidepressant class of medications SNRIs
works by binding to presynaptic SERT and
NET to inhibit them from reuptake of sero-
tonin and norepinephrine to increase their
levels in the synaptic cleft
21. In addition to MDD SNRIs treat
, Walden 6630 Psychopharmacology Midterm Study Guide
Study online at https://quizlet.com/_986h43
Anxiety and neuropathic pain (periph-
eral neuropathy)
22. Medication specific indications of duloxetine: urinary incontinence and Fibromyalgia
23. Medication specific indications of venlafax- social anxiety, panic disorders, PTSD,
ine: OCD, postmenopausal hot flashes
24. Six common side effects of SNRIs include: Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
25. Severe side effect of SNRIs in children/adoles- suicidal ideation
cents under age 25 years old:
26. Life threatening adverse effect of SNRIs, es- Serotonin Syndrome
pecially when used in combination with other
serotonergic drugs:
27. This SNRI is an inhibitor of Cytochrome P450 venlafaxine
enzymes:
28. This SNRI is hepatotoxic: duloxetine
29. MAOIs increase the levels of: Serotonin, Norepinephrine, and
Dopamine
30. Norepinephrine regulates: alertness and focus
31. Dopamine regulates: cognitive function, motivation, and
awakeness
32. In the synaptic cleft, Monoamine Oxidase A Serotonin, Norepinephrine, and
breaks down: Dopamine
33. Dopamine
