HIV-OPPORTUNI
STIC
INFECTIONS
,COMPETENCY-6.3 & 6.4
❖ Describe and discuss the relationship between
CD4 count and the risk of opportunistic
infections
❖ Describe & discuss the pathogenesis, evolution
and clinical features of common HIV related
opportunistic infections.
,INTRODUCTION
, ❖ HIV itself is associated with a wide variety of
clinical manifestations, and opportunistic diseases
❖ CD4 count is useful in differential diagnosis
❖ example, in a patient with a pulmonary infiltrate
and a CD4 count of 350 cells/mm3, pulmonary
tuberculosis is a likely diagnosis and PCP is very
unlikely, but if the patient's CD4 count is 50
cells/mm3 both PCP and tuberculosis are likely.
STIC
INFECTIONS
,COMPETENCY-6.3 & 6.4
❖ Describe and discuss the relationship between
CD4 count and the risk of opportunistic
infections
❖ Describe & discuss the pathogenesis, evolution
and clinical features of common HIV related
opportunistic infections.
,INTRODUCTION
, ❖ HIV itself is associated with a wide variety of
clinical manifestations, and opportunistic diseases
❖ CD4 count is useful in differential diagnosis
❖ example, in a patient with a pulmonary infiltrate
and a CD4 count of 350 cells/mm3, pulmonary
tuberculosis is a likely diagnosis and PCP is very
unlikely, but if the patient's CD4 count is 50
cells/mm3 both PCP and tuberculosis are likely.
