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Nursing Clinical Judgment Study Guide
(2025–2026)
1. What signs and symptoms does the nurse anticipate to find in a patient diagnosed with
tuberculosis? Select all that apply.
A. Lethargy
B. Dyspnea
C. Weight gain
D. Night sweats
2. The nurse is caring for a patient with pneumonia. Which intervention is priority for
airway management?
A. Administer analgesics
B. Elevate head of bed 30-45 degrees
C. Apply sequential compression devices
D. Encourage fluid restriction
3. A patient receiving rifampin for tuberculosis therapy reports orange urine. What is the
nurse's best response?
A. This indicates renal failure
B. This is an expected side effect
C. Discontinue the medication immediately
D. Administer activated charcoal
4. The nurse recognizes hypoxia in a patient based on which early clinical finding? Select
all that apply.
A. Tachypnea
B. Bradycardia
C. Restlessness
D. Hypertension
5. What patient education is essential for a client on multi-drug therapy for active
tuberculosis?
A. Take medications with antacids
B. Complete full course of therapy
C. Skip doses if feeling better
D. Share medications with family members
,6. During an H5N1 bird flu outbreak, what precaution does the nurse implement first for
suspected cases?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Standard precautions only
7. The nurse assesses a patient with viral pneumonia. Which ABG result indicates the
need for immediate oxygen therapy?
A. pH 7.38, PaO2 95 mmHg
B. pH 7.48, PaO2 60 mmHg
C. pH 7.32, PaO2 85 mmHg
D. pH 7.40, PaO2 100 mmHg
8. A patient with tuberculosis asks about drug-resistant strains. What is the most
accurate response?
A. Caused by poor hygiene only
B. Results from incomplete treatment
C. Prevented by vitamins
D. Transmitted by casual contact
9. The nurse prioritizes care for a hypoxic patient using Maslow's hierarchy. What is the
first action?
A. Assess pain level
B. Administer supplemental oxygen
C. Provide emotional support
D. Check blood glucose
10. What side effect of isoniazid requires the nurse to monitor liver function tests?
A. Orange discoloration
B. Hepatotoxicity
C. Photosensitivity
D. Peripheral neuropathy only
11. For a patient with community-acquired pneumonia, which vaccination does the nurse
recommend?
A. MMR
B. Pneumococcal
C. Varicella
D. Tdap
12. The nurse delegates tasks to an LPN caring for a stable pneumonia patient. Which
task is appropriate?
A. Initial assessment
B. Administer IV antibiotics
,C. Discharge planning
D. Write care plan
13. A patient with tuberculosis refuses isolation. What legal principle guides the nurse's
response?
A. Autonomy overrides public safety
B. Public health law may mandate isolation
C. Patient rights supersede all
D. No intervention needed
14. Evidence-based practice for preventing ventilator-associated pneumonia includes
which intervention?
A. Routine antibiotics
B. Elevate HOB 30-45 degrees
C. Subglottic suctioning only
D. Daily sedation holidays
15. The nurse uses Lewin's change theory to implement a new oxygen weaning protocol.
What is the first phase?
A. Refreezing
B. Unfreezing
C. Moving
D. Evaluation
16. The nurse receives report on four patients. Which requires immediate intervention?
A. COPD patient with SpO2 92% on room air
B. Asthma patient with wheezes bilaterally
C. Pneumonia patient with SpO2 85% despite 2L oxygen
D. TB patient with productive cough
17. A patient with active tuberculosis asks when they can return to work. What is the
nurse's best response?
A. After 1 week of therapy
B. After 2-3 weeks of therapy and negative sputum
C. Immediately if asymptomatic
D. After completing full treatment
18. Which nursing diagnosis is priority for the patient with pneumonia and ineffective
airway clearance? Select all that apply.
A. Impaired gas exchange
B. Acute pain
C. Ineffective airway clearance
D. Activity intolerance
, 19. The nurse educates a patient newly diagnosed with latent tuberculosis. Which
statement indicates understanding?
A. "I need airborne precautions at home"
B. "I must take medication to prevent active disease"
C. "I'm contagious to my family now"
D. "No treatment is needed"
20. During rounds, the nurse finds a hypoxic patient unresponsive to verbal stimuli. What
is the first action?
A. Check blood glucose
B. Assess respiratory rate and oxygen saturation
C. Administer naloxone
D. Start chest compressions
21. A patient on rifampin therapy should be instructed to do what regarding body fluids?
A. Report red urine immediately
B. Expect orange-red discoloration
C. Drink extra fluids to prevent this
D. Avoid all fluids
22. The nurse monitors which laboratory value closely in patients taking isoniazid?
A. Blood glucose
B. Liver function tests
C. Renal panel
D. CBC
23. Pyrazinamide therapy requires monitoring for which major side effect?
A. Ototoxicity
B. Hepatotoxicity
C. Nephrotoxicity
D. Cardiotoxicity
24. A patient reports numbness in fingers while on TB medications. Which drug is most
likely responsible?
A. Rifampin
B. Isoniazid
C. Pyrazinamide
D. Ethambutol
25. Ethambutol requires baseline and monthly assessment of which function?
A. Hearing
B. Vision
C. Liver
D. Renal