PCB 3023 UCF Exam 4
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1. Programmed cell death occurs
A. by means of an intracellular suicide program
B. rarely and selectively only during animal development
C. only in unhealthy or abnormal cells
D. only during embryonic development: A. by means of an intracellular suicide program
2. What kind of apoptosis regulator is Bcl-2?
A. propoptotic
B. antiapoptotic
C. initiator caspase
D. effector caspase: B. antiapoptotic
3. Which statement about apoptosis is true?
A. Cells that constitutively express Bel2 will be more prone to undergo apopto-
sis.
B. The prodomain of procaspases contains the catalytic activity necessary for
procaspase activation.
C. Bax and Bak promote apoptosis by binding to procaspases in the apopto-
some.
D. Apoptosis is promoted by the release of cytochrome c into the cytosol from
mitochondria.: D. Apoptosis is promoted by the release of cytochrome c into the cytosol from mitochondria.
4. An adult hematopoietic stem cell found in the bone
marrow
A. will occasionally produce epidermal cells when necessary
B. can produce only red blood cells
C. can undergo self-renewing divisions for the lifetime of a healthy animal
D. will express all the same transcription factors as those found in an unfertil-
ized egg: C. can undergo self-renewing divisions for the lifetime of a healthy animal
5. What affect would an overactive Wnt signaling pathway have on the intestinal
epithelium?
A. loss of stem cells for renewal of gut lining
B. formation of polyps by promoting inappropriate proliferation of gut stem
cells
C. formation of too many absorptive cells
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D. formation of too few secretory cells: B. formation of polyps by promoting inappropriate
proliferation of gut stem cells
6. Would you consider formation of the outer layer of skin cells to be due to
programmed cell death?
A. yes
B. no: A. yes
7. How do reproductive cloning and therapeutic cloning differ?
A. The DNA in the nucleus of cells produced for therapeutic cloning is genetical-
ly identical to the donor genome, whereas in cells produced for reproductive
cloning it is not.
B. Reproductive cloning requires a supply of fertilized donor egg cells, whereas
therapeutic cloning requires unfertilized egg cells.
C. Embryos are placed into foster mothers during reproductive cloning but not
during therapeutic cloning.
D. Therapeutic cloning requires nuclear transplantation, whereas reproductive
cloning does not.: A. The DNA in the nucleus of cells produced for therapeutic cloning is genetically identical
to the donor genome, whereas in cells produced for reproductive cloning it is not
C. Embryos are placed into foster mothers during reproductive cloning but not during therapeutic cloning.
8. Which statement about the cell cycle is false?
A. Once a cell decides to enter the cell cycle, the time from start to finish is the
same in all eukaryotic cells.
B. An unfavorable environment can cause cells to arrest in G1.
C. A cell has more DNA during G2 than it did in G1.
D. The cleavage divisions that occur in an early embryo have a modified cell
cycle with essentially no G1 or G2 phases.: D. The cleavage divisions that occur in an early embryo
have a modified cell cycle with essentially no G1 or G2 phases.
9. One approach to killing cancer cells is to induce apoptosis. Which of the
following are reasonable approaches that researchers can take to induce apop-
tosis in cancer cells?
A.activating the Bax protein
B.inhibiting the Bcl2 protein
C.inhibiting the p53 protein
, PCB 3023 UCF Exam 4
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D.inhibiting the G1-cyclin-dependent kinase protein: A.activating the Bax protein
B.inhibiting the Bcl2 protein
10. The size of a human organ often depends on which factor?Choose one or
more:
A) the death of cells during its development
B) the proliferation of cells during its development
C) the number of chromosomes in the cells of the organ: A) the death of cells during its
development
B) the proliferation of cells during its development
11. Which of the following statements is true?Choose one:
A. Many cells die by apoptosis in many normal, adult human tissues.
B. Many cells die by necrosis during normal animal development.
C. Many cells die by necrosis in many normal, adult human tissues.: A. Many cells
die by apoptosis in many normal, adult human tissues.
12. Determine whether the following statement is true or false: Apoptosis de-
pends on a tightly regulated proteolytic cascade.: True
13. Which of the following statements is false?Choose one:
A. Some death-inhibiting members of the Bcl2 family inhibit apoptosis by
blocking cytochrome c release from mitochondria.
B. Bax and Bak are death-promoting members of the Bcl2 family that induce
the release of cytochrome c from mitochondria into the cytosol.
C. The death-promoting members of the Bcl2 family include Bcl2 itself.
D. Some Bcl2 family members promote apoptosis, whereas others inhibit apop-
tosis.: C. The death-promoting members of the Bcl2 family include Bcl2 itself.
14. External signals can stimulate apoptosis by activating a set of cell-surface
receptors known as what?Choose one:
A) caspase receptors
B) death receptors
C) Bax receptors
D) suicide receptors: B) death receptors
15. Which of the following statements describes how mitogens operate?Choose
one:
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1. Programmed cell death occurs
A. by means of an intracellular suicide program
B. rarely and selectively only during animal development
C. only in unhealthy or abnormal cells
D. only during embryonic development: A. by means of an intracellular suicide program
2. What kind of apoptosis regulator is Bcl-2?
A. propoptotic
B. antiapoptotic
C. initiator caspase
D. effector caspase: B. antiapoptotic
3. Which statement about apoptosis is true?
A. Cells that constitutively express Bel2 will be more prone to undergo apopto-
sis.
B. The prodomain of procaspases contains the catalytic activity necessary for
procaspase activation.
C. Bax and Bak promote apoptosis by binding to procaspases in the apopto-
some.
D. Apoptosis is promoted by the release of cytochrome c into the cytosol from
mitochondria.: D. Apoptosis is promoted by the release of cytochrome c into the cytosol from mitochondria.
4. An adult hematopoietic stem cell found in the bone
marrow
A. will occasionally produce epidermal cells when necessary
B. can produce only red blood cells
C. can undergo self-renewing divisions for the lifetime of a healthy animal
D. will express all the same transcription factors as those found in an unfertil-
ized egg: C. can undergo self-renewing divisions for the lifetime of a healthy animal
5. What affect would an overactive Wnt signaling pathway have on the intestinal
epithelium?
A. loss of stem cells for renewal of gut lining
B. formation of polyps by promoting inappropriate proliferation of gut stem
cells
C. formation of too many absorptive cells
, PCB 3023 UCF Exam 4
Study online at https://quizlet.com/_fdu516
D. formation of too few secretory cells: B. formation of polyps by promoting inappropriate
proliferation of gut stem cells
6. Would you consider formation of the outer layer of skin cells to be due to
programmed cell death?
A. yes
B. no: A. yes
7. How do reproductive cloning and therapeutic cloning differ?
A. The DNA in the nucleus of cells produced for therapeutic cloning is genetical-
ly identical to the donor genome, whereas in cells produced for reproductive
cloning it is not.
B. Reproductive cloning requires a supply of fertilized donor egg cells, whereas
therapeutic cloning requires unfertilized egg cells.
C. Embryos are placed into foster mothers during reproductive cloning but not
during therapeutic cloning.
D. Therapeutic cloning requires nuclear transplantation, whereas reproductive
cloning does not.: A. The DNA in the nucleus of cells produced for therapeutic cloning is genetically identical
to the donor genome, whereas in cells produced for reproductive cloning it is not
C. Embryos are placed into foster mothers during reproductive cloning but not during therapeutic cloning.
8. Which statement about the cell cycle is false?
A. Once a cell decides to enter the cell cycle, the time from start to finish is the
same in all eukaryotic cells.
B. An unfavorable environment can cause cells to arrest in G1.
C. A cell has more DNA during G2 than it did in G1.
D. The cleavage divisions that occur in an early embryo have a modified cell
cycle with essentially no G1 or G2 phases.: D. The cleavage divisions that occur in an early embryo
have a modified cell cycle with essentially no G1 or G2 phases.
9. One approach to killing cancer cells is to induce apoptosis. Which of the
following are reasonable approaches that researchers can take to induce apop-
tosis in cancer cells?
A.activating the Bax protein
B.inhibiting the Bcl2 protein
C.inhibiting the p53 protein
, PCB 3023 UCF Exam 4
Study online at https://quizlet.com/_fdu516
D.inhibiting the G1-cyclin-dependent kinase protein: A.activating the Bax protein
B.inhibiting the Bcl2 protein
10. The size of a human organ often depends on which factor?Choose one or
more:
A) the death of cells during its development
B) the proliferation of cells during its development
C) the number of chromosomes in the cells of the organ: A) the death of cells during its
development
B) the proliferation of cells during its development
11. Which of the following statements is true?Choose one:
A. Many cells die by apoptosis in many normal, adult human tissues.
B. Many cells die by necrosis during normal animal development.
C. Many cells die by necrosis in many normal, adult human tissues.: A. Many cells
die by apoptosis in many normal, adult human tissues.
12. Determine whether the following statement is true or false: Apoptosis de-
pends on a tightly regulated proteolytic cascade.: True
13. Which of the following statements is false?Choose one:
A. Some death-inhibiting members of the Bcl2 family inhibit apoptosis by
blocking cytochrome c release from mitochondria.
B. Bax and Bak are death-promoting members of the Bcl2 family that induce
the release of cytochrome c from mitochondria into the cytosol.
C. The death-promoting members of the Bcl2 family include Bcl2 itself.
D. Some Bcl2 family members promote apoptosis, whereas others inhibit apop-
tosis.: C. The death-promoting members of the Bcl2 family include Bcl2 itself.
14. External signals can stimulate apoptosis by activating a set of cell-surface
receptors known as what?Choose one:
A) caspase receptors
B) death receptors
C) Bax receptors
D) suicide receptors: B) death receptors
15. Which of the following statements describes how mitogens operate?Choose
one:
