Update) | Advanced Pathophysiology Review
Guide |Verified Questions & Correct Answers |
Grade A – Chamberlain College
How does blood flow through the heart?
Deoxygenated venous blood → Sup. Vena Cava → Right Atrium →Tricuspid (AV) →Empties
into R. Ventricle (& it contracts) → Blood ejected through Pulmonary Valve → Pulmonary
Artery → Lungs to be Oxygenated → Pulmonary Veins → L. Atrium → Mitral (AV) → L.
Ventricle (pumps with each contraction) → Aortic Valve → Aorta → Body
What is systole?
Contraction of the heart which pumps blood
Diastole
Relaxation of the heart
What produces S1 and S2 sound?
closing of the heart valves
What produces S1?
The mitral and tricuspid valves which close in systole
, NR507 / NR 507 Midterm Exam V2 (2026–2027
Update) | Advanced Pathophysiology Review
Guide |Verified Questions & Correct Answers |
Grade A – Chamberlain College
What produces S2 sound?
The closing of the aortic and pulmonic valves in diastole
What is cardiac output?
the volume of blood pumped out by each ventricle per minute
What is stroke volume?
amount of blood pumped out by each ventricle with contraction
What determines cardiac output?
stroke volume and heart rate
What is preload?
the degree of stretch on the heart before it contracts, related to ventricular filling, end diastolic
pressure, amount of blood entering the ventricle during diastole
What is afterload?
resistance left ventricle must overcome to circulate blood
, NR507 / NR 507 Midterm Exam V2 (2026–2027
Update) | Advanced Pathophysiology Review
Guide |Verified Questions & Correct Answers |
Grade A – Chamberlain College
What is contractility?
Normal ability of muscle to contract at a given force for a given stretch. It is independent of
preload/afterload
Will sustained tachycardia result in increased or decreased stroke volume?
Decreased
What conditions can result in decreased contractility?
Ischemia, acidosis, cardiomyopathy
What can cause increase afterload?
HTN, pulmonary disease, damage to the aortic valve
What has the most immediate effect on afterload?
HTN
Why would hemorrhaging cause decreased afterload?
Decreased volume of blood creates less resistance