NURS 300 CUMULATIVE FINAL EXAM (New Drugs
+ ALL KEY DRUGS) – Questions With Complete
Solutions
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Terms in this set (276)
Acetaminophen (Nonopioid Slows the production of prostaglandins in CNS
Analgesic) MOA
Acetaminophen USES Fever and Pain
Acetaminophen Contraindications Liver disease and Alcohol
Acetaminophen Complications 1. Acute liver toxicity
2. Overdose: liver failure
Early and Late Stage Signs of Liver -Early: N/V/D. Sweating, RUQ discomfort
Toxicity -Late: hepatic failure, coma, jaundice, death
Acetaminophen N.I. -Do not exceed 4g a day for normal, healthy person
-Undernourished: Max - 3g
->3 EtOH - 2g
-Monitor bilirubin, ALT/AST due to Liver Toxicity
Acetaminophen Memory Aid "3 A's"
-Acute liver toxicity (early and late)
-Acetylcysteine (Antidote)
-Alcohol
Naproxen and Ketorolac (NSAID) Inhibition of Cox-1 and Cox-2
MOA
Naproxen and Ketorolac Use Inflammation suppression, analgesic, fever
,Naproxen and Ketorolac Anticoagulants + Glucocorticoids (Increase risk of
Contraindication bleeding), PUD, Alcohol, HTN meds
Naproxen and Ketorolac -GI discomfort (dyspepsia, abd pain, heartburn,
Complications nausea)
-Bleeding Risk of GI
-PUD
-Impaired kidney function
Naproxen and Ketorolac N.I. -Take with food
-Take with PPI or H2 receptor antagonist if used long
term to protect the stomach
Ketorolac Specific N.I. "The Kettle Burns for 2-3 Min every 5 Days"
-Push slowly and dilute with NS
-DON'T give UNDER 2-3 MIN or more than 5 DAYS
(leads to kidney damage)
Aspirin (NSAID) MOA Highly effective on Cox-1, but does inhibit Cox-2
Aspirin Use -Decreases platelet aggregation --> protects against
ischemic stroke and CAD
-Inflammation suppression, analgesic, fever
Aspirin Contraindication -Anticoagulants, other NSAIDs, PUD, Alcohol
-Children under 16 (Reye Syndrome)
Aspirin Complications -Salicylism: tinnitus, sweating, H/A, dizziness, Resp
Alkalosis
-Reye Syndrome: Massive inflammation of organs
-Toxicity
,NSAID Memory Aid "BIG Party by the ASH tree"
B: bleeding risk
I: impaired kidney
G: GI bleed
P: preventative medication
A: anticoagulants
S: steroids (breakdown stomach lining)
H: HTN meds (decrease T/E of BP med)
Morphine (Opioid Agonist) MOA Activates MU Receptors
Morphine Use Relief of pain, sedation, decrease bowel motility,
cough suppression
Morphine Contraindications -CNS depressants, Anti-HTN meds, Physical
dependance
-Biliary Tract Surgery (Causes Biliary Colic)
Morphine Complications and N.I. "COR HOUSE"
C: constipation -> fiber, H2O
O: opioid triad (coma, resp distress, pinpoint pupils)
R: RR <12, hold, assess, narcan
H: hypotension -> hold if <90/50
O: OH -> move slowly
U: urinary retention -> every 4 hr, fluids
S: sedation
E: emesis/nausea -> push 3-5 min, nausea med prior,
take w/ food
Amitriptyline (Tricyclic blocks reuptake of serotonin and norepinephrine
Antidepressant) MOA
Amitriptyline Use -Neuropathic Pain
-Depression
-Fibromyalgia
Amitriptyline Contraindications -Glaucoma
, Amitriptyline Complications -Anticholinergic
-Sedation
-Orthostatic Hypotension
Amitriptyline N.I. -Chew gum or sips of water, bathroom every 4 hours,
fiber + hydration
-Take at night, don't drive
-Stand up slow
Amitriptyline Memory Aid "Ami tripped in the desert because she was tired and
couldn't see"
Gabapentin (Anticonvulsant) MOA Increases GABA
Gabapentin Use -Neuropathic pain
-Anticonvulsant
Gabapentin Contraindication History of drug/alcohol abuse
Gabapentin Complications "Being So Not Real"
B: bone marrow suppression
S: sedation
N: n/v/d
R: rash
Gabapentin N.I. (in order of BSNR)
-Monitor CBC + Platelets, bruising, bleeding,
epistaxis
-Take at night
-Take with food
-Contact provider if rash occurs
Albuterol (Beta 2 Adrenergic Agonist) Beta 2 Agonist - enhances bronchodilation resulting
MOA in smooth muscle dilation
Albuterol Use -Bronchospasms
-Asthma
-COPD
-Exercise induced asthma
+ ALL KEY DRUGS) – Questions With Complete
Solutions
Save
Terms in this set (276)
Acetaminophen (Nonopioid Slows the production of prostaglandins in CNS
Analgesic) MOA
Acetaminophen USES Fever and Pain
Acetaminophen Contraindications Liver disease and Alcohol
Acetaminophen Complications 1. Acute liver toxicity
2. Overdose: liver failure
Early and Late Stage Signs of Liver -Early: N/V/D. Sweating, RUQ discomfort
Toxicity -Late: hepatic failure, coma, jaundice, death
Acetaminophen N.I. -Do not exceed 4g a day for normal, healthy person
-Undernourished: Max - 3g
->3 EtOH - 2g
-Monitor bilirubin, ALT/AST due to Liver Toxicity
Acetaminophen Memory Aid "3 A's"
-Acute liver toxicity (early and late)
-Acetylcysteine (Antidote)
-Alcohol
Naproxen and Ketorolac (NSAID) Inhibition of Cox-1 and Cox-2
MOA
Naproxen and Ketorolac Use Inflammation suppression, analgesic, fever
,Naproxen and Ketorolac Anticoagulants + Glucocorticoids (Increase risk of
Contraindication bleeding), PUD, Alcohol, HTN meds
Naproxen and Ketorolac -GI discomfort (dyspepsia, abd pain, heartburn,
Complications nausea)
-Bleeding Risk of GI
-PUD
-Impaired kidney function
Naproxen and Ketorolac N.I. -Take with food
-Take with PPI or H2 receptor antagonist if used long
term to protect the stomach
Ketorolac Specific N.I. "The Kettle Burns for 2-3 Min every 5 Days"
-Push slowly and dilute with NS
-DON'T give UNDER 2-3 MIN or more than 5 DAYS
(leads to kidney damage)
Aspirin (NSAID) MOA Highly effective on Cox-1, but does inhibit Cox-2
Aspirin Use -Decreases platelet aggregation --> protects against
ischemic stroke and CAD
-Inflammation suppression, analgesic, fever
Aspirin Contraindication -Anticoagulants, other NSAIDs, PUD, Alcohol
-Children under 16 (Reye Syndrome)
Aspirin Complications -Salicylism: tinnitus, sweating, H/A, dizziness, Resp
Alkalosis
-Reye Syndrome: Massive inflammation of organs
-Toxicity
,NSAID Memory Aid "BIG Party by the ASH tree"
B: bleeding risk
I: impaired kidney
G: GI bleed
P: preventative medication
A: anticoagulants
S: steroids (breakdown stomach lining)
H: HTN meds (decrease T/E of BP med)
Morphine (Opioid Agonist) MOA Activates MU Receptors
Morphine Use Relief of pain, sedation, decrease bowel motility,
cough suppression
Morphine Contraindications -CNS depressants, Anti-HTN meds, Physical
dependance
-Biliary Tract Surgery (Causes Biliary Colic)
Morphine Complications and N.I. "COR HOUSE"
C: constipation -> fiber, H2O
O: opioid triad (coma, resp distress, pinpoint pupils)
R: RR <12, hold, assess, narcan
H: hypotension -> hold if <90/50
O: OH -> move slowly
U: urinary retention -> every 4 hr, fluids
S: sedation
E: emesis/nausea -> push 3-5 min, nausea med prior,
take w/ food
Amitriptyline (Tricyclic blocks reuptake of serotonin and norepinephrine
Antidepressant) MOA
Amitriptyline Use -Neuropathic Pain
-Depression
-Fibromyalgia
Amitriptyline Contraindications -Glaucoma
, Amitriptyline Complications -Anticholinergic
-Sedation
-Orthostatic Hypotension
Amitriptyline N.I. -Chew gum or sips of water, bathroom every 4 hours,
fiber + hydration
-Take at night, don't drive
-Stand up slow
Amitriptyline Memory Aid "Ami tripped in the desert because she was tired and
couldn't see"
Gabapentin (Anticonvulsant) MOA Increases GABA
Gabapentin Use -Neuropathic pain
-Anticonvulsant
Gabapentin Contraindication History of drug/alcohol abuse
Gabapentin Complications "Being So Not Real"
B: bone marrow suppression
S: sedation
N: n/v/d
R: rash
Gabapentin N.I. (in order of BSNR)
-Monitor CBC + Platelets, bruising, bleeding,
epistaxis
-Take at night
-Take with food
-Contact provider if rash occurs
Albuterol (Beta 2 Adrenergic Agonist) Beta 2 Agonist - enhances bronchodilation resulting
MOA in smooth muscle dilation
Albuterol Use -Bronchospasms
-Asthma
-COPD
-Exercise induced asthma
