PORTAGE
PATHOPHYSIOLOGY EXAM
1
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, Question 1
True/False:
Persistent metaplasia can lead to dysplasia.
Correct Answer
true
Rationale:
Persistent metaplasia occurs when a normal cell type is replaced by an abnormal cell type that is not typical for the tissue, leading to a
chronic disruption in normal cellular function. Over time, this disruption can increase the risk of genetic mutations that can progress to
dysplasia, a precursor to cancer.
Question 2
True/False:
Barrett esophagus is an example of dysplasia.
Correct Answer
false (Barrett's esophagus is METAplasia)
Rationale:
Barrett's esophagus is an example of metaplasia, a change in the type of cells lining the esophagus, whereas dysplasia refers to an
abnormal development of cells within the same tissue type. In Barrett's esophagus, the normal squamous epithelium is replaced by
columnar epithelium, making it a classic case of metaplasia rather than dysplasia.
Question 3
True/False:
Persistent dysplasia eventually results in cancer.
Correct Answer
true
Rationale:
Persistent dysplasia is a type of abnormal cell growth that, if left untreated, can continue to progress and eventually develop into
cancer due to accumulating genetic mutations. This gradual process demonstrates the malignant transformation of dysplastic cells as
they progress towards a fully malignant phenotype, resulting in cancer.
Question 4
True/False:
Hypertrophy can occur under normal and pathological conditions.
Correct Answer
true
Rationale:
Hypertrophy refers to the increase in size of muscle fibers or cells, which can occur in response to various stimuli, including normal
physiological demands, such as exercise, or pathological conditions, like muscle damage or disease. This adaptability of muscle tissue
to different conditions is why hypertrophy can indeed occur under both normal and pathological circumstances.
Trusted by thousands of students and professionals worldwide Page 2 of 8
PATHOPHYSIOLOGY EXAM
1
20+ (Updated for 2026) Exam Prep
Pack | A+ Questions & Verified Answers
100% Guarantee Pass
This Exam contains: portage pathophysiology exam
✓ 1
✓ 100% Accurate Questions and Answers
✓ 100% Guarantee Pass - Verified by Experts
✓ Each Question Includes The Correct Answer
✓ Expert-Verified
Trusted by thousands of students and professionals worldwide Page 1 of 8
, Question 1
True/False:
Persistent metaplasia can lead to dysplasia.
Correct Answer
true
Rationale:
Persistent metaplasia occurs when a normal cell type is replaced by an abnormal cell type that is not typical for the tissue, leading to a
chronic disruption in normal cellular function. Over time, this disruption can increase the risk of genetic mutations that can progress to
dysplasia, a precursor to cancer.
Question 2
True/False:
Barrett esophagus is an example of dysplasia.
Correct Answer
false (Barrett's esophagus is METAplasia)
Rationale:
Barrett's esophagus is an example of metaplasia, a change in the type of cells lining the esophagus, whereas dysplasia refers to an
abnormal development of cells within the same tissue type. In Barrett's esophagus, the normal squamous epithelium is replaced by
columnar epithelium, making it a classic case of metaplasia rather than dysplasia.
Question 3
True/False:
Persistent dysplasia eventually results in cancer.
Correct Answer
true
Rationale:
Persistent dysplasia is a type of abnormal cell growth that, if left untreated, can continue to progress and eventually develop into
cancer due to accumulating genetic mutations. This gradual process demonstrates the malignant transformation of dysplastic cells as
they progress towards a fully malignant phenotype, resulting in cancer.
Question 4
True/False:
Hypertrophy can occur under normal and pathological conditions.
Correct Answer
true
Rationale:
Hypertrophy refers to the increase in size of muscle fibers or cells, which can occur in response to various stimuli, including normal
physiological demands, such as exercise, or pathological conditions, like muscle damage or disease. This adaptability of muscle tissue
to different conditions is why hypertrophy can indeed occur under both normal and pathological circumstances.
Trusted by thousands of students and professionals worldwide Page 2 of 8
