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methylphenidate (concerta/ritalin)
-produces CNS and respiratory stimulation
-ADHD, narcolepsy
-cardiac abnormalities, hyperthyroidism
-increased attention span for ADHD
-hypertension, tachycardia, palpitations
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1 CNS stimulant key drug #3 2 histamine receptors
3 adrenergic decongestants MOA 4 antihistamine indications
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Terms in this set (146)
,histamine receptors causes vasodilation, increased GI and respiratory
secretions, and increased capillary permeability.
two main receptors are H1 and H2
antihistamines drugs that directly compete with histamine for
specific receptor sites and act as H1 blockers
Antihistamines MOA binding at unoccupied receptors and are more
effective at preventing histamine effects than
reversing them
antihistamine properties reduce capillary permeability, itching, wheal-and-
flare formation, have drying effects, and may cause
sedation
antihistamine indications used for palliative treatment of nasal allergies,
allergic rhinitis, motion sickness, PD, sleep disorders,
sneezing, and runny nose
antihistamines adverse effects dry mouth, difficulty urinating, constipation, vision
changes, and drowsiness
sedating antihistamines older antihistamines that work peripherally and
centrally and have anticholinergic effects, making
them more effective in some cases
example of sedating antihistamine Diphenhydramine (Benadryl)
nonsedating antihistamines developed to reduce unwanted sedation; work
peripherally with fewer CNS effects and have a
longer duration of action
examples of nonsedating Fexofenadine (Allegra)
antihistamines Loratadine (Claritin)
Cetirizine (Zyrtec)
what are the 3 main types of adrenergics, anticholinergics, corticosteroids
decongestants
, decongestants indications used for relief of nasal congestion from rhinitis,
common cold, sinusitis, hay fever, and other allergies
adrenergic decongestants MOA constrict small blood vessels in nasal tissues,
shrinking swollen mucous membranes and improving
drainage
oral adrenergic decongestants have prolonged effects but delayed onset, are less
potent than topical, and do not cause rebound
congestion
example of oral adrenergic Pseudoephedrine (Sudafed)
decongestants
topical adrenergic decongestants have prompt onset and are potent, but sustained use
causes rebound congestion
example of topical adrenergic Phenylephrine (Neo-Synephrine)
decongestants
Corticosteroid decongestants MOA Blocks local inflammatory response and decreases
congestion
examples of corticosteroids nasal Beclomethasone dipropionate, flunisolide (Nasalide),
decongestants fluticasone (Flonase)
Decongestants adverse effects nervousness, insomnia, palpitations, tremors, and
systemic effects; may cause mucosal dryness and
irritation
productive cough a congested cough that removes excessive
secretions
nonproductive cough a dry cough without mucus production
antitussives drugs that stop or reduce coughing and are used
only for nonproductive coughs or when coughing is
harmful