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Terms in this set (209)
What is the mechanism of action of They bind to muscarinic receptors and mimic
muscarinic agonists? acetylcholine.
Name three drugs that are classified Bethanechol, pilocarpine, acetylcholine.
as muscarinic agonists.
What are the indications for using Urinary retention.
muscarinic agonists?
List some adverse effects of Hypotension, bradycardia, increased secretions.
muscarinic agonists.
What are the contraindications for GI/U obstruction, peptic ulcer disease, asthma,
muscarinic agonists? hypotension, coronary insufficiency.
What drugs is the muscarinic agonists Atropine
antidote?
What is the MOA of muscarinic They inhibit acetylcholine from binding to muscarinic
antagonists? receptors.
Name four drugs that are classified as Atropine, glycopyrrolate, scopolamine, oxybutynin.
muscarinic antagonists.
What are the indications for using Pre-anesthesia, eye disorders, overactive bladder,
muscarinic antagonists? bradycardia, muscarinic excess reversal.
,List some adverse effects of Agitation, blurry vision, constipation, confusion, low
muscarinic antagonists. secretions.
What are the contraindications for Glaucoma, GI/U obstruction, Myasthenia Gravis.
muscarinic antagonists?
What drug is the antidote of Physostigmine
muscarinic antagonists?
What is the MOA of cholinesterase They prevent cholinesterase from inactivating
inhibitors? acetylcholine, increasing its availability.
Name two drugs that are classified as Neostigmine, physostigmine.
cholinesterase inhibitors.
What are the indications for using Myasthenia Gravis, Alzheimer's, glaucoma,
cholinesterase inhibitors? Parkinson's.
List some adverse effects of Neuromuscular blockade, muscarinic excess.
cholinesterase inhibitors.
What are the contraindications for GI/U obstruction, peptic ulcer disease, asthma,
cholinesterase inhibitors? hypotension, coronary insufficiency.
What drug can be used for reversal of Atropine.
cholinesterase inhibitors?
What is the mechanism of action of They bind directly to norepinephrine receptors and
adrenergic agonists? mimic the effects of norepinephrine.
What are the indications for using Hypotension, shock, bronchospasm, acute renal
adrenergic agonists? failure, cirrhosis, barbiturate intoxication, anaphylaxis,
local anesthetic, bleeding.
What are some adverse effects of Hypertension.
adrenergic agonists?
, What is the mechanism of action of They bind to adrenergic receptors and block
adrenergic antagonists? norepinephrine.
Name two drugs that are classified as Phentolamine, propranolol.
adrenergic antagonists.
What are the indications for using Hypertension, sympathetic nervous system tumor,
adrenergic antagonists? angina, myocardial infarction, dysrhythmias,
hyperthyroidism, stage fright, glaucoma.
List some adverse effects of Orthostatic hypotension, reflex tachycardia, nasal
adrenergic antagonists. congestion, bradycardia, bronchoconstriction.
What are the contraindications for Asthma, chronic obstructive pulmonary disease.
adrenergic antagonists?
What is the mechanism of action of They block sodium and chloride reabsorption and
loop diuretics? prevent water reabsorption in the loop of Henle.
What is a commonly used loop Furosemide.
diuretic?
What are the indications for using Pulmonary edema, heart failure, second-line diuretic.
loop diuretics?
List some adverse effects of loop Hypotension, ototoxicity, hypokalemia, dehydration.
diuretics.
What is the mechanism of action of They block sodium reabsorption in the loop of Henle
thiazide diuretics? and prevent water reabsorption in the distal
convoluted tubule.
What is a commonly used thiazide Hydrochlorothiazide (HCTZ).
diuretic?
What are the indications for using First choice for essential hypertension, mild to
thiazide diuretics? moderate edema.