NUR 141 FINAL MTC QUESTIONS WITH COMPLETE
SOLUTIONS
Which brain regions are stimulated by phentermine to suppress
appetite?
Phentermine stimulates the satiety center in the hypothalamus
and limbic region.
phentermine adverse effects
1. tachycardia
2. nervousness
3. hyperactivity
4. pulmonary hypotension
5. dry mouth
what is the time frame for tolerance of phentermine?
4-6 weeks
phentermine interactions
1. tricyclic antidepressants
2. CNS stimulants
3. alcohol
4. sympathomimetic drugs
5. GI acidifying agents
why should patients with a hx of glaucoma avoid phentermine?
risk of pupillary dilation
,why should patients with a history of drug abuse avoid
phentermine?
due to the similarity of amphetamines
why should diabetics be cautious with phentermine?
reduce sympathetic nervous system stimulation, may need to
increase insulin
what drug class is orlistat?
lipase inhibitor
orlistat MOA
binds to gastric and pancreatic lipases (enzyme that breaks down
fat to store) in GI tract. slows absorption of ingested fat,
improves serum cholesterol levels, fat excreted through feces
orlistat adverse effects
1. abd pain
2. cramping
3. oily stool
4. fecal incontinence
5. increased defecation
orlistat interactions
1. cyclosporins
2. levothyroxine
3. pravastatin
4. amiodarone
What should patients avoid while taking orlistat?
,Highly fatty meals
How should orlistat be taken in relation to meals?
Take one capsule with one main meal or up to 1 hour after a
meal, up to three capsules daily
What should you do if you miss a meal while taking orlistat?
Omit the dose
When should a multivitamin containing fat soluble vitamins be
taken in relation to orlistat?
At least two hours before or after taking orlistat
How much water should orlistat be taken with?
A full glass of water
peptic ulcer disease etiology
infection with H. pylori, use of NSAID's, stress
PUD manifestations (gastric ulcers)
dull aching pain immediately after eating, bloating, indigestion,
nausea, painless bleeding
PUD manifestations (duodenal ulcers)
worse when stomach is empty at night, heartburn, bloating, abd
pain, burning sensation
GERD etiology
incompetent lower esophageal sphincter due to foods, fluids,
meds, smoking, recumbent posture, pregnancy
, GERD manifestations
pyrosis, regurgitation of acidic fluid into mouth, especially after
meals and at night
medications for GERD
1. mylanta
2. cimetidine
3. famotidine
4. ranitidine
5. omeprazole
Mylanta MOA
neutralizes gastric acid
Mylanta indications
prevent and treat PUD, GERD, esophagitis, heartburn, gastritis,
GI bleeding
mylanta adverse effects
1. constipation
2. hypophosphatemia
3. osteomalacia
4. diarrhea
5. hypermagnesemia
mylanta interactions
can prevent absorption of most drugs taken at the same time,
take meds 1-2 hours apart
When should Mylanta be taken?
SOLUTIONS
Which brain regions are stimulated by phentermine to suppress
appetite?
Phentermine stimulates the satiety center in the hypothalamus
and limbic region.
phentermine adverse effects
1. tachycardia
2. nervousness
3. hyperactivity
4. pulmonary hypotension
5. dry mouth
what is the time frame for tolerance of phentermine?
4-6 weeks
phentermine interactions
1. tricyclic antidepressants
2. CNS stimulants
3. alcohol
4. sympathomimetic drugs
5. GI acidifying agents
why should patients with a hx of glaucoma avoid phentermine?
risk of pupillary dilation
,why should patients with a history of drug abuse avoid
phentermine?
due to the similarity of amphetamines
why should diabetics be cautious with phentermine?
reduce sympathetic nervous system stimulation, may need to
increase insulin
what drug class is orlistat?
lipase inhibitor
orlistat MOA
binds to gastric and pancreatic lipases (enzyme that breaks down
fat to store) in GI tract. slows absorption of ingested fat,
improves serum cholesterol levels, fat excreted through feces
orlistat adverse effects
1. abd pain
2. cramping
3. oily stool
4. fecal incontinence
5. increased defecation
orlistat interactions
1. cyclosporins
2. levothyroxine
3. pravastatin
4. amiodarone
What should patients avoid while taking orlistat?
,Highly fatty meals
How should orlistat be taken in relation to meals?
Take one capsule with one main meal or up to 1 hour after a
meal, up to three capsules daily
What should you do if you miss a meal while taking orlistat?
Omit the dose
When should a multivitamin containing fat soluble vitamins be
taken in relation to orlistat?
At least two hours before or after taking orlistat
How much water should orlistat be taken with?
A full glass of water
peptic ulcer disease etiology
infection with H. pylori, use of NSAID's, stress
PUD manifestations (gastric ulcers)
dull aching pain immediately after eating, bloating, indigestion,
nausea, painless bleeding
PUD manifestations (duodenal ulcers)
worse when stomach is empty at night, heartburn, bloating, abd
pain, burning sensation
GERD etiology
incompetent lower esophageal sphincter due to foods, fluids,
meds, smoking, recumbent posture, pregnancy
, GERD manifestations
pyrosis, regurgitation of acidic fluid into mouth, especially after
meals and at night
medications for GERD
1. mylanta
2. cimetidine
3. famotidine
4. ranitidine
5. omeprazole
Mylanta MOA
neutralizes gastric acid
Mylanta indications
prevent and treat PUD, GERD, esophagitis, heartburn, gastritis,
GI bleeding
mylanta adverse effects
1. constipation
2. hypophosphatemia
3. osteomalacia
4. diarrhea
5. hypermagnesemia
mylanta interactions
can prevent absorption of most drugs taken at the same time,
take meds 1-2 hours apart
When should Mylanta be taken?
