SUCCED
A-LEVEL BIOLOGY
Paper 2 – Advanced Topics in Biology
Time allowed: 2 hours
CANDIDATE NUMBER
CNTER NUMBER
DATE
SECTION
Instructions:
• Answer all questions.
• Use black ink or ball-point pen.
• Write your answers in the spaces provided.
• Show all working for calculations.
• The maximum mark for this paper is 85.
• Marks for each question are shown in brackets.
• Quality of written communication will be assessed in extended responses.
Section A: Structured Questions
,SUCCED
Question 1 – Enzymes and Metabolism (10 marks)
1. (a) Explain how enzyme structure enables specificity in
substrate binding. (3 marks)
2. (b) Describe the effect of temperature on enzyme
activity, including denaturation. (3 marks)
3. (c) A student investigates the effect of pH on enzyme X.
Sketch and label the expected graph of enzyme activity
against pH. (4 marks)
, SUCCED
Question 2 – Cell Division (12 marks)
2. (a) Outline the stages of mitosis in order. (4 marks)
4. (b) Explain two differences between mitosis and
meiosis. (4 marks)
5. (c) A mutation occurs during meiosis. Discuss how this
could contribute to genetic variation. (4 marks)
Question 3 – Transport in Plants (10 mark
A-LEVEL BIOLOGY
Paper 2 – Advanced Topics in Biology
Time allowed: 2 hours
CANDIDATE NUMBER
CNTER NUMBER
DATE
SECTION
Instructions:
• Answer all questions.
• Use black ink or ball-point pen.
• Write your answers in the spaces provided.
• Show all working for calculations.
• The maximum mark for this paper is 85.
• Marks for each question are shown in brackets.
• Quality of written communication will be assessed in extended responses.
Section A: Structured Questions
,SUCCED
Question 1 – Enzymes and Metabolism (10 marks)
1. (a) Explain how enzyme structure enables specificity in
substrate binding. (3 marks)
2. (b) Describe the effect of temperature on enzyme
activity, including denaturation. (3 marks)
3. (c) A student investigates the effect of pH on enzyme X.
Sketch and label the expected graph of enzyme activity
against pH. (4 marks)
, SUCCED
Question 2 – Cell Division (12 marks)
2. (a) Outline the stages of mitosis in order. (4 marks)
4. (b) Explain two differences between mitosis and
meiosis. (4 marks)
5. (c) A mutation occurs during meiosis. Discuss how this
could contribute to genetic variation. (4 marks)
Question 3 – Transport in Plants (10 mark
