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HESI Dosage Calculations Exam 2026: Complete Practice Questions with Answers | HESI Drug Calculations Review

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Master the HESI Dosage Calculations Exam with this comprehensive practice guide featuring complete questions and step-by-step answers for 2026. Covering all essential dosage calculation types including heparin protocol calculations (units/kg, loading doses, infusion rates), weight-based medication dosing (mg/kg/day, divided doses), IV infusion rates (ml/hr, gtt/min), medication reconstitution, percentage solutions and dilutions, body surface area (BSA) calculations, Parkland formula for burn resuscitation, pediatric dosing, insulin and heparin drips, critical care titrations (mcg/kg/min, mg/min), IVPB and secondary infusions, enteral feedings and tube feedings, fluid intake and output calculations, and medication conversions between grams, milligrams, micrograms, and units. Each question includes detailed rationales showing the step-by-step mathematical process. Perfect for nursing students preparing for the HESI Dosage Calculations exam, NCLEX, or clinical practice.

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HESI Dosage Calculations Exam: 150+
Questions & Correct Answers 2026 (
Update) (PDF)

HESI Dosage Calculations




2026

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,Heparin protocol is prescribed for a client weighing 90 kg. Per protocol, the
heparin loading dose is 60 units/kg IV rounded to the nearest 100 units, with
a maximum loading dose of 4,000 units. The heparin vial is labeled 5,000
units/ml. How many ml should the nurse administer? (Enter the numeric
value only. If rounding is required, round to the nearest tenth.)
false Item 51164 By Sheila Duncan Heparin Protocol:
Heparin loading dose: 60 units/kg IV, rounded to the nearest 100 units,
followed by a maintenance infusion of 12 units/kg/hr, rounded to the nearest
100 units/hr. The maximum bolus is 4,000 units and the maximum initial
infusion is 1000 units/hr. ..........ANSWER.......Determine the client loading
dose: 60 units x 90 kg = 5,400 unit.
Per protocol, use the maximum loading dose of 4,000 units, and calculate
the client's dose using the formula D/H x Q = 4,000 units / 5,000 units x 1 ml
= 4/5 = 0.8 ml
or Use ratio and proportion: 5,000 : 1 ml :: 4,000 : X
X = 0.8 ml


A child weighing 28.4 kg is in hypertensive crisis. The healthcare provider
prescibes methyldopa (Aldomet) 40 mg/kg/day IV in 4 divided doses. The
pharmacy provides a 50 mg/ml injection vial. How many ml should the nurse
administer? (Enter numeric value only. If rounding is required, round to the
nearest tenth.) ..........ANSWER.......First calculate the total mg dose/day: 40
mg x 28.4 kg = 1136 mg/day
Next divide the total mg into the 4 dosages for the day: 1136 mg/4 doses =
284 mg/dose
Using the Desired/Have formula: 284 mg/50mg x 1 ml = 5.68 ml/ dose,
rounded to 5.7 ml.

,A client with multiple sclerosis and muscle spasms receives a prescription for
baclofen (Kemstro) 30 mg PO daily. The medication is supplied from the
pharmacy in 20 mg scored tablets. How many tablets should the nurse
administer? (Enter numeric value only. If rounding is required, round to the
nearest tenth.) ..........ANSWER.......Use ratio and proportion, 30 mg : X
tablets = 20 mg : 1 tablet
20X = 30
X = 1.5


A client with dehydration receives a prescription for an IV of Lactated
Ringer's 1,000 ml to be administered over 8 hours. The nurse should program
the infusion pump to deliver how many ml/hour? (Enter numeric value only,
using whole number.) ..........ANSWER.......Use the ratio of: 1000 ml : 8 hours
:: X : 1 hour
1000/X :: 8/1
X = 125 ml/hour


The nurse plans to administer labetalol hydrochloride (Trandate) 0.3 grams
PO to a client with hypertension. Trandate is available in 200 mg scored
tablets. How many tablets should the nurse administer? (Enter numeric
value only.) ..........ANSWER.......First convert grams to milligrams using the
known conversion: 1 gram = 1000 mg.
0.1 gram = 100 mg as 0.3 gram = 300 mg
Next using the formula, Desired/Available x 1 tablet =
300 mg/200 mg x 1 = 1.5 tablets


A 110-pound, adult female is admitted to the Emergency Center after
receiving burns to 40 percent of her body. Using the Parkland formula, the
client's fluid requirements for the first 24 hours after injury is calculated

, using Lactated Ringer's 4 ml solution x Body weight (in kilograms) x Percent
burn. The client should receive one-half of the 24-hour calculated fluid
volume in the first 8 hours of treatment. The nurse should set the infusion
pump to deliver how many ml/hour during the first 8 hours? (Enter the
numerical value only. If rounding is required, round to the nearest whole
number.) ..........ANSWER.......Using the Parkland formula, the client's fluid
requirements for the first 24 hours after injury is calculated using 4 ml
lactated Ringer's solution x Body weight (in kilograms) x Percent burn
Convert 110 pounds to kg = .2 = 50 kg
4 ml x 50 kg x 40 = 8,000 ml
One-half in first 8 hours = 4,000 ml
4,000 ml / 8 hours = 500 = 500 ml/hour


A client who has heart failure with paroxysmal atrial tachycardia is receiving
digoxin (Lanoxin) 0.45 mg IV as the inital digitalizing dose. The pharmacy
provides 0.25 mg/ml. How many ml should the nurse administer? (Enter
numeric value only. If rounding is required, round to the nearest tenth.)
..........ANSWER.......Using the formula D/H x Q = 0.45 mg/0.25 mg x 1 mL =
1.8 ml


Mineral oil U.S.P 30 ml PO daily for 3 days is prescribed for a client who is
experiencing severe constipation. The dose cup is marked in tablespoons.
How many tablespoons should the nurse administer? (Enter numeric value
only.) ..........ANSWER.......15 ml equals 1 Tablespoon. Use the ratio equation:
15 ml : 1 Tbs :: 30 ml : X
:: 1 / X
15X = 30
X = 2 Tablespoons

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