Actual Questions with Verified Answers –
Complete Practice Examination – Portage
Learning – Graded A+
Part I: Multiple Choice (30 Questions, 2 points each)
Q1: In humans, widow's peak (pointed hairline) is dominant over straight hairline. If two
heterozygous parents have a child, what is the probability that the child will have a
straight hairline?
A. 0%
B. 25% [CORRECT]
C. 50%
D. 75%
Correct Answer: B
Rationale: Both parents are heterozygous (Ww). A Punnett square shows: 25% WW
(widow's peak), 50% Ww (widow's peak), 25% ww (straight hairline). Only the
homozygous recessive genotype (ww) expresses the straight hairline phenotype. Option
A is incorrect because there is a chance of the recessive phenotype. Option C
represents the probability of a heterozygous genotype, not the straight hairline
phenotype. Option D represents the probability of having widow's peak.
,Q2: A genetic counselor is analyzing a family with a rare autosomal recessive disorder.
Which of the following statements about carrier parents is CORRECT?
A. Both parents must be homozygous dominant
B. Both parents must be heterozygous carriers [CORRECT]
C. One parent must be affected and one must be unaffected
D. Both parents must be affected to have an affected child
Correct Answer: B
Rationale: For two unaffected parents to have a child with an autosomal recessive
disorder, both must be carriers (heterozygous Aa). Each child has a 25% chance of
being affected (aa). Option A is incorrect because homozygous dominant parents (AA)
cannot produce affected offspring. Option C is incorrect because an affected parent
(aa) would have the disorder. Option D is incorrect because if both parents were
affected, they would all have the disorder, not just some children.
Q3: Red-green color blindness is an X-linked recessive trait. A color-blind man and a
woman with normal vision (whose father was color-blind) have a son. What is the
probability that their son will be color-blind?
A. 0%
B. 25%
C. 50% [CORRECT]
D. 100%
,Correct Answer: C
Rationale: The man is XᶜY (color-blind). The woman must be a carrier (XᶜX) because her
father was color-blind (XᶜY) and passed his Xᶜ to all daughters. For a son: he receives Y
from father and either X or Xᶜ from mother (50% chance each). Therefore, 50% chance
of XᶜY (color-blind) or XY (normal). Option A is incorrect because there is a definite
chance. Option B confuses this with the 25% risk for a daughter to be affected. Option D
would only occur if the mother were affected (XᶜXᶜ), which she is not.
Q4: In snapdragons, flower color shows incomplete dominance. Red flowers (RR)
crossed with white flowers (WW) produce all pink flowers (RW). If two pink-flowered
plants are crossed, what phenotypic ratio is expected in the offspring?
A. 1 red : 2 pink : 1 white [CORRECT]
B. 3 red : 1 white
C. 9 red : 3 pink : 3 white : 1 other
D. All pink
Correct Answer: A
Rationale: Incomplete dominance results in a heterozygous phenotype intermediate
between the homozygous parents. The cross RW × RW produces: 25% RR (red), 50% RW
(pink), 25% WW (white), giving a 1:2:1 phenotypic ratio. Option B is the classic
Mendelian ratio for complete dominance. Option C is a dihybrid ratio. Option D would
occur if there were complete dominance or if the trait showed blending inheritance
without segregation.
Q5: Which nitrogenous base is found in RNA but NOT in DNA?
, A. Adenine
B. Guanine
C. Thymine
D. Uracil [CORRECT]
Correct Answer: D
Rationale: RNA contains uracil (U) instead of thymine (T). Both nucleic acids contain
adenine, guanine, and cytosine. During transcription, DNA's thymine is replaced by uracil
in the mRNA transcript. This is a fundamental difference between the two nucleic acids.
Options A, B, and C are all found in DNA.
Q6: During DNA replication, which enzyme is responsible for synthesizing new DNA
strands by adding nucleotides in the 5' to 3' direction?
A. Helicase
B. DNA ligase
C. DNA polymerase [CORRECT]
D. Primase
Correct Answer: C
Rationale: DNA polymerase is the enzyme that catalyzes phosphodiester bond
formation, adding nucleotides only to the 3'-OH end of a growing chain (5' to 3'
synthesis). Helicase (A) unwinds the double helix. DNA ligase (B) joins Okazaki
fragments on the lagging strand. Primase (D) synthesizes RNA primers. The directional