PCB 3233 Chapter 12 practice university of central
florida Questions With Correct Solutions,
Already Passed!!
1. Which type of cell is most likely to accumulate mutations over time,
potentially leading to cancer?
o A) Post-mitotic cells
o B) Progenitor cells
o C) Stem cells
o D) Erythrocytes
2. What cellular characteristic makes adult stem cells prime targets for
mutagenesis and tumorigenesis?
o A) High division rate
o B) Short lifespan
o C) Slow division rate but long lifespan
o D) Resistance to mutation accumulation
3. Progenitor cells are less likely to contribute to tumor formation
because:
o A) They are quiescent and do not divide
o B) They have high levels of repair enzymes
o C) They are quickly flushed out and have short lifespans
o D) They undergo symmetrical division
4. Which process best describes why tumor induction in skin is only
effective if stem cells retain the memory of initiator treatment?
o A) Asymmetrical division
o B) Symmetrical division
o C) Long-term retention of mutagenic history
o D) Quick replacement and turnover
5. The resistance of quiescent stem cells to anti-mitotic treatments like
5-fluorouracil (5-Fu) suggests:
o A) Active proliferating cells play a major role in tumor
development
o B) Quiescent stem cells are likely to retain mutations leading to
cancer
o C) 5-Fu is ineffective for cancer treatment
o D) Stem cells do not respond to chemotherapy
6. Which cells are least likely to be exposed to environmental mutagens
due to tissue organization?
o A) Stem cells
o B) Keratinocytes
o C) Progenitor cells
o D) Erythrocytes
7. Exogenous mutagens refer to mutations caused by:
o A) Replication errors
o B) Environmental agents or chemicals
, o C) Mitochondrial malfunction
o D) None of the above
florida Questions With Correct Solutions,
Already Passed!!
1. Which type of cell is most likely to accumulate mutations over time,
potentially leading to cancer?
o A) Post-mitotic cells
o B) Progenitor cells
o C) Stem cells
o D) Erythrocytes
2. What cellular characteristic makes adult stem cells prime targets for
mutagenesis and tumorigenesis?
o A) High division rate
o B) Short lifespan
o C) Slow division rate but long lifespan
o D) Resistance to mutation accumulation
3. Progenitor cells are less likely to contribute to tumor formation
because:
o A) They are quiescent and do not divide
o B) They have high levels of repair enzymes
o C) They are quickly flushed out and have short lifespans
o D) They undergo symmetrical division
4. Which process best describes why tumor induction in skin is only
effective if stem cells retain the memory of initiator treatment?
o A) Asymmetrical division
o B) Symmetrical division
o C) Long-term retention of mutagenic history
o D) Quick replacement and turnover
5. The resistance of quiescent stem cells to anti-mitotic treatments like
5-fluorouracil (5-Fu) suggests:
o A) Active proliferating cells play a major role in tumor
development
o B) Quiescent stem cells are likely to retain mutations leading to
cancer
o C) 5-Fu is ineffective for cancer treatment
o D) Stem cells do not respond to chemotherapy
6. Which cells are least likely to be exposed to environmental mutagens
due to tissue organization?
o A) Stem cells
o B) Keratinocytes
o C) Progenitor cells
o D) Erythrocytes
7. Exogenous mutagens refer to mutations caused by:
o A) Replication errors
o B) Environmental agents or chemicals
, o C) Mitochondrial malfunction
o D) None of the above
