2026
Next■Generation NCLEX (NGN) Style Practice Exam – 300
Questions
Question 1 – Renal
Which client should the nurse assess first?
A. A client with stable hypertension requesting pain medication
B. A client with heart failure and oxygen saturation of 88%
C. A postoperative client requesting assistance to ambulate
D. A client awaiting discharge instructions
Rationale: Clients with compromised oxygenation are the highest priority according to ABCs.
Question 2 – Maternal-Newborn
A nurse is caring for a client with pneumonia. Which nursing actions are appropriate? (Select all
that apply)
A. Monitor oxygen saturation
B. Assess level of consciousness
C. Administer prescribed medications
D. Encourage increased fluid intake
E. Document findings in the EHR
Rationale: These actions support safe monitoring, intervention, and documentation for clients
experiencing this condition.
Question 3 – Maternal-Newborn
A nurse is caring for a client with diabetes mellitus. Which intervention should the nurse perform
first?
A. Assess vital signs
B. Administer oxygen
C. Notify the provider
D. Educate the client
Correct Answer: Assess vital signs
Rationale: Vital signs provide baseline data and identify instability. This is prioritized according to
ABCs and nursing safety principles in patients with diabetes mellitus.
,Question 4 – Mental Health
Case Study
Assessment Value
Blood Pressure 158/92
Heart Rate 110 bpm
Respirations 26/min
Oxygen Saturation 90%
Based on the EHR data, which action should the nurse perform first for a client with suspected
asthma?
A. Assess vital signs
B. Administer oxygen
C. Notify the provider
D. Educate the client
Rationale: Abnormal assessment findings indicate respiratory compromise requiring immediate
oxygen support.
Question 5 – Infection Control
Bow■Tie NGN Item
A client with preeclampsia develops worsening symptoms. Identify the priority condition, 2 actions,
and 2 monitoring parameters.
Priority Condition: Acute deterioration
Action 1: Administer oxygen
Action 2: Assess vital signs
Monitor: Oxygen saturation
Monitor: Respiratory status
Rationale: These actions support stabilization and continuous assessment of the deteriorating
patient.
Question 6 – Pediatrics
Bow■Tie NGN Item
A client with asthma develops worsening symptoms. Identify the priority condition, 2 actions, and 2
monitoring parameters.
Priority Condition: Acute deterioration
Action 1: Administer oxygen
Action 2: Assess vital signs
Monitor: Oxygen saturation
, Monitor: Respiratory status
Rationale: These actions support stabilization and continuous assessment of the deteriorating
patient.
Question 7 – Neurological
Case Study
Assessment Value
Blood Pressure 158/92
Heart Rate 110 bpm
Respirations 26/min
Oxygen Saturation 90%
Based on the EHR data, which action should the nurse perform first for a client with suspected
chronic kidney disease?
A. Assess vital signs
B. Administer oxygen
C. Notify the provider
D. Educate the client
Rationale: Abnormal assessment findings indicate respiratory compromise requiring immediate
oxygen support.
Question 8 – Infection Control
Case Study
Assessment Value
Blood Pressure 158/92
Heart Rate 110 bpm
Respirations 26/min
Oxygen Saturation 90%
Based on the EHR data, which action should the nurse perform first for a client with suspected
heart failure?
A. Assess vital signs
B. Administer oxygen
C. Notify the provider
D. Educate the client
Rationale: Abnormal assessment findings indicate respiratory compromise requiring immediate
oxygen support.
, Question 9 – Endocrine
A nurse is caring for a client with sepsis. Which nursing actions are appropriate? (Select all that
apply)
A. Monitor oxygen saturation
B. Assess level of consciousness
C. Administer prescribed medications
D. Encourage increased fluid intake
E. Document findings in the EHR
Rationale: These actions support safe monitoring, intervention, and documentation for clients
experiencing this condition.
Question 10 – Endocrine
Bow■Tie NGN Item
A client with COPD develops worsening symptoms. Identify the priority condition, 2 actions, and 2
monitoring parameters.
Priority Condition: Acute deterioration
Action 1: Administer oxygen
Action 2: Assess vital signs
Monitor: Oxygen saturation
Monitor: Respiratory status
Rationale: These actions support stabilization and continuous assessment of the deteriorating
patient.
Question 11 – Pediatrics
A nurse is caring for a client with heart failure. Which nursing actions are appropriate? (Select all
that apply)
A. Monitor oxygen saturation
B. Assess level of consciousness
C. Administer prescribed medications
D. Encourage increased fluid intake
E. Document findings in the EHR
Rationale: These actions support safe monitoring, intervention, and documentation for clients
experiencing this condition.
Question 12 – Respiratory
A nurse is caring for a client with stroke. Which nursing actions are appropriate? (Select all that
apply)
A. Monitor oxygen saturation