QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES LATEST 2026-2027 (VERIFIED ANSWERS)|
ALREADY GRADED A+
Prepare for your ATI and NCLEX exams with 100 expertly crafted oxygenation practice questions! Each question comes
with multiple-choice options, the correct answer clearly highlighted, and detailed rationales to help you understand key
concepts in respiratory care, oxygen therapy, and hypoxemia management. Perfect for nursing students looking to
strengthen their respiratory nursing knowledge and boost exam confidence.
1. A nurse is caring for a client with chronic obstructive pulmonary disease (COPD). Which action should
the nurse take to promote oxygenation?
A. Encourage the client to breathe rapidly
B. Position the client in a high-Fowler’s position
C. Restrict fluids to prevent pulmonary edema
D. Have the client lie flat in bed
Rationale: High-Fowler’s position allows maximum lung expansion, facilitating better oxygenation in clients
with COPD.
2. A client is receiving oxygen via nasal cannula at 4 L/min. The nurse should monitor for which
complication?
A. Hypoventilation
B. Dry mucous membranes
C. Bradycardia
D. Hypertension
,Rationale: Oxygen delivery via nasal cannula can dry out the mucous membranes, causing discomfort and
irritation.
3. The nurse is teaching a client with asthma how to use a metered-dose inhaler (MDI). Which instruction
is correct?
A. Exhale fully before activating the inhaler
B. Shake the inhaler after inhaling
C. Hold breath for 5 seconds after inhalation
D. Rinse mouth only once per week
Rationale: Exhaling before inhalation ensures maximal delivery of medication to the lungs.
4. A nurse is assessing a client with pneumonia. Which finding indicates impaired oxygenation?
A. Blood pressure 118/76 mmHg
B. Oxygen saturation 88% on room air
C. Heart rate 78 bpm
D. Temperature 37.2°C
Rationale: Oxygen saturation below 90% indicates hypoxemia and impaired oxygenation.
5. Which statement by a client indicates understanding of oxygen therapy safety at home?
A. “I can smoke while using oxygen as long as it is low-flow.”
B. “I should keep oxygen at least 2 meters from any open flame.”
C. “It’s okay to use petroleum jelly on my nostrils.”
D. “I do not need to check oxygen tubing for kinks.”
Rationale: Oxygen supports combustion; maintaining distance from flames prevents fire hazards.
6. A client with chronic bronchitis reports difficulty breathing when lying down. Which nursing action is
appropriate?
A. Encourage supine positioning
B. Elevate the head of the bed
C. Limit fluid intake
D. Encourage shallow breathing
Rationale: Elevating the head improves diaphragmatic movement and reduces orthopnea in clients with
respiratory conditions.
, 7. The nurse is teaching pursed-lip breathing to a client with COPD. What is the purpose of this technique?
A. Increase tidal volume by rapid breaths
B. Prevent airway collapse during exhalation
C. Increase oxygen consumption
D. Promote shallow breathing
Rationale: Pursed-lip breathing prolongs exhalation, preventing airway collapse and improving oxygenation.
8. A client with hypoxemia is receiving oxygen via a simple face mask at 6 L/min. Which assessment
requires immediate intervention?
A. Skin pink and warm
B. Respiratory rate 20/min
C. Mask fit is loose and oxygen is leaking
D. Lung sounds clear
Rationale: A loose mask reduces oxygen delivery, which can worsen hypoxemia.
9. Which statement indicates a client understands incentive spirometer use?
A. “I should exhale as fast as possible.”
B. “I should inhale slowly and hold my breath.”
C. “I only need to use it once per day.”
D. “I should sit in a lying position while using it.”
Rationale: Slow inhalation and breath-holding maximizes lung expansion, preventing atelectasis.
10.A client with pulmonary edema has crackles in both lungs and a respiratory rate of 28. Which
intervention should the nurse implement first?
A. Encourage deep breathing exercises
B. Administer oxygen as prescribed
C. Offer oral fluids
D. Assist the client to walk
Rationale: Administering oxygen immediately addresses hypoxemia and supports tissue oxygenation.
11.Which position is best to optimize oxygenation in a client with unilateral lung disease?
A. Supine
B. Lying on the unaffected side