What do PRRs recognize? - ✔️✔️PAMPs or DAMPs
PAMP - ✔️✔️Pathogen-Associated Molecular Pattern
DAMP - ✔️✔️Damage-Associated Molecular Pattern
TLR - ✔️✔️Toll-Like Receptors
What happens when TLR bind foreign patterns? - ✔️✔️Signaling cascades are
activated (PAMP; releases cytokines) -> expression of factors that cause inflammation
4 Commensal Floras - ✔️✔️- Good bacteria
- Antibiotics
- Defensins
- Cathelicidins
PRR - ✔️✔️Pattern-Recognition Receptors
6 Stimuli for Acute Inflammation - ✔️✔️- Infections & Microbial Toxins
- Trauma
- Physical & Chemical Agents
- Tissue Necrosis
- Foreign Bodies
- Immune Reactions
5 Key Signs of Acute Inflammation - ✔️✔️- Rubor
- Calor
- Tumor
- Dolor
- Loss of function