CMN 548 UNIT 5 ENTRANCE EXAMINATION WITH RESEARCHED COMPLETE QUESTIONS AND 100% CORRECT VERIFIED ANSWERS ALREADY GRADED A+

CMN 548 UNIT 5 ENTRANCE EXAMINATION WITH
RESEARCHED COMPLETE QUESTIONS AND 100%
CORRECT VERIFIED ANSWERS ALREADY GRADED
A+

Potency - CORRECT ANSWER>>>refers to the relative dose required to achieve certain
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effects, not to the efficacy of a drug
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Agonist (full agonist) - CORRECT ANSWER>>>A drug that binds to a specific receptor
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producing an effect identical to that usually produced by the neurotransmitter affecting that
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receptor
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Pharmacodynamics - CORRECT ANSWER>>>The time course and intensity of a drug's
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effect/what the drug does to the body
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Pharmacokinetics - CORRECT ANSWER>>>What the body does to a drug
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Tolerance - CORRECT ANSWER>>>Develops over time a need to use increased doses of a
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medication/drug to maintain a clinical effect. Or, a decreased sensitivity to adverse effects of
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a drug
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Stevens-Johnson Syndrome - CORRECT ANSWER>>>A systemic, immune-mediated
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reaction that can be fatal or result in permanent scarring or blindness
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Antagonist - CORRECT ANSWER>>>A compound that blinds to a receptor that blocks or
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reduces the action of another substance at the receptor site
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,Hyponatremia - CORRECT ANSWER>>>Common symptoms of this medication side effect
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include confusion, agitation, and lethargy. (tx with oxcarbazepine & SSRIs)
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Therapeutic index - CORRECT ANSWER>>>ratio of the median toxic dose to the median
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effective dose
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Somnolence - CORRECT ANSWER>>>Daytime sleepiness
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Black Box Warning - CORRECT ANSWER>>>This warning reflects that a medication may
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cause a serious or even life-threatening side effect
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Partial or Mixed Agonist - CORRECT ANSWER>>>A compound that elicits a partial
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pharmacological response at the receptor site involved
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Remission - CORRECT ANSWER>>>The degree of improvement to below the syndromal
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threshold of a disorder
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Paradoxical - CORRECT ANSWER>>>A response to a drug that represents the clinical
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effect opposite of what is expected
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Inverse agonist - CORRECT ANSWER>>>An agent that binds to the same receptor site as
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Man agonist but produces the opposite pharmacological effect
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4 major transmitters - CORRECT ANSWER>>>Dopamine, Serotonin, GABA,
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Norepinephrine
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,Dopamine transmitter affects? - CORRECT ANSWER>>>affects mood, Psychosis, ADHD,
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Addiction
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Serotonin transmitter affects? - CORRECT ANSWER>>>Depression, aggression, OCD,
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Panic, GAD, Social Anxiety, PTSD, Violence, Sexual dysfunction, substance addiction
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Norepinephrine affects? - CORRECT ANSWER>>>Affects mood, anxiety, psychosis, ADHD
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(part), drug withdrawal
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GABA affects? - CORRECT ANSWER>>>Fear, anxiety, worry
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Irreversible MAOIs Types - CORRECT ANSWER>>>MAOa and MAOb
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Irreversible MAOIs medications - CORRECT ANSWER>>>Phenelzine (Nardil)
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isocarboxazid (Marplan)
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tranylcypromine (Parnate) M




A single dose of MAOIs may persist in its inhibition of MAO for how long? - CORRECT
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M ANSWER>>>because they irreversibly inactivate MAOs, the therapeutic effect of a single dose
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of irreversible MAOIs may persist for as long as 2 weeks
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What are the most frequent adverse effects of MAOIs? - CORRECT
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ANSWER>>>orthostatic hypotension, insomnia, weight gain, edema, sexual dysfunction M M M M M M M




Reversible MAOIs (RIMAs) medications? - CORRECT ANSWER>>>Moclobemide (Maerix)
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, How long will it take to recover MAO activity after a final dose of RIMA? - CORRECT
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M ANSWER>>>MAO activity recovers completely 24-48 hrs after the last dose of a RIMA M M M M M M M M M M M M




MAOIs are used to treat what conditions? - CORRECT ANSWER>>>depression
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panic disorder
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social phobia
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M bulimia

nervosa ptsd
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anginal pain M




atypical facial pain M M




M migraine

adhd

idiopathic orthostatic hypotension M M




Depression associated with TBI
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Treatment for MAOI induced orthostatic hypotension? - CORRECT ANSWER>>>Avoid
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caffeine
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intake of 2L of fluid/day
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M addition of dietary salt M M M




M adjust HTN meds M M




M support stocking M




severe cases *tx with fludrocortisone (Florinef) a mineralcorticoid
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How long should the NP wait to begin another tx for depression when stopping an MAOI to
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M begin another MAOI or SSRI? - CORRECT ANSWER>>>irreversible MAOI-wait 14 days
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MAO activity recovers completely 24-48 hrs after last dose of RIMA
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