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Class & exam notes - Biomedical Science, digestion and renal science

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These comprehensive and well-structured notes are designed specifically for first-year Biomedical Science students studying at British-based universities. They cover the core physiological systems and foundational pharmacology required to build a strong understanding of human biology. The notes include detailed yet easy-to-understand explanations of the cardiovascular, respiratory, digestive, renal, and nervous systems, alongside essential introductory pharmacology concepts. Complex topics are simplified into clear sections, making them ideal for revision, exam preparation, and consolidating lecture material. Inside these notes you will find: • Clear explanations of key physiological mechanisms • Organized summaries of major body systems • Essential pharmacology principles relevant to first-year modules • Simplified breakdowns of complex biomedical concepts • Structured content that follows typical UK biomedical science curricula • Perfect material for quick revision before exams These notes are perfect for students who want to save time, understand difficult concepts faster, and revise efficiently. Whether you’re preparing for assessments or trying to strengthen your understanding of core biomedical topics, this resource provides a concise yet comprehensive study companion. Ideal for Biomedical Science, Medical Science, and related Life Science students in UK universities.

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Excretion

Anatomy, lecture 01

The excretion system consists of kidneys, ureters, bladders and urethra.

Kidneys and ureters present in posterior abdominal region

Distal end of ureters, bladders and urethra are pelvic urinary organs, kidneys and
abdominal part of ureters are retroperitoneal.

- Retroperitoneal structures (retro means behind)
Structures that lie posterior to the parietal peritoneum (peritoneum is a
membrane that covers the abdominopelvic cavity)
Primary retroperitoneal are structures that develop posterior to peritoneum
such as kidneys and suprarenal gland (also called adrenal glands)
Perinephric fat protects the kidneys along with the peritoneum

- The kidneys
Filters blood to produce urine, 2 kidneys, T12-L3 vertebrae, right kidney
slightly lower than left due to presence of live

The right kidney has a suprarenal gland on its anterior and diaphragm on its
posterior along with a subcostal nerve

The left kidney also has a suprarenal gland but also has spleen, stomach,
pancreas on its anterior, and same things on its posterior as with the right
kidney

Anatomy of the kidney

1. Has red/brown fibrous capsule
2. Hilum which contains renal vein, branches form renal artery, and renal
pelvis
3. A lymphatic system around the vessels

Kidney consists of an outer renal cortex completely surrounding the inner
renal medulla

Renal cortex projects INTO the inner part of the kidney forming renal columns

These columns divide renal medulla into renal pyramids

,Minor calyces receive urine from papillary ducts




Nephrons are the functional unit of the kidney, each kidney has 800,000 to a
million nephrons

Kidneys CANNOT regenerate nephrons following injuries

Cortical nephrons are nephrons that have glomeruli located in the outer
cortex, enveloped by peritubular capillaries to transport blood

Juxtamedullary nephrons have glomeruli that lie deep in the renal cortex near
the medulla, associated with organized set of blood vessels called vasa recta

,- Renal arteries in the kidneys

Right and left renal arteries from the aorta between L1-L2 level

Divides into anterior and posterior branches and segmental arteries that
enter hilum

Right artery is longer than the left

Arteries INSIDE the kidney include- lobar arteries, interlobar, interlobular,
arcuate and afferent glomerular arterioles

, - Veins and lymph of the kidneys
Renal veins empty into the inferior vena cava, left vein which is longer than
the right passes behind the splenic vein and body of the pancreas. Made by
the connection the L gonadal and L suprarenal vein.
R renal vein passes behind the descending duodenum

The L vein can be compressed of there is an aneurysm in any of those 2
vessels. This is called nutcracker syndrome

Lymph drains to the aortic nodes around the origin of the renal artery

- The ureters
Ureters convey urine from the kidney to the bladder
They are muscular ducts
Urine is propelled by the contractions of the ureter wall and by filtration
pressure from the glomeruli
Pathway- from hilum over the psoas muscle surface, crosses the bifurcation
at common iliac artery at the sarco-iliac joint enter the bladder at trigone
area

Areas of constriction-

1. Junction between the ureters and renal pelvis
2. Where ureters cross the pelvic brim
3. At the trigone where they enter the wall of the bladder

These areas are important as they can be sites of obstruction

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