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Semmelweis Entrance exam Past Paper & Quide

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This admission exam material is based on last year’s oral and written exam questions. The Oral section includes the interview questions I personally received last year along with my sample answers, as well as additional topics and questions that other applicants were asked during their oral exams. The Written section contains a compiled collection of past exam questions. Since the question stems and answer choices have been organized exactly as they originally appeared, you can think of this as a highly realistic reconstruction of the actual question sets that were given on the exam. Overall, this material is designed to help applicants understand the style, level, and structure of the admission test in a practical and effective way.

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Voorbeeld van de inhoud

Semmelweis University

More than 250 Exam
Entrance years in the
service of health

, TABLE OF CONTENTS


01 Interviw
ADMISSION TOPIC 02
2025.APR.23 05
2025.MAR (Topics) 15
2025.APR (Topics) 18
02 Chemistry
2024 (01~36) 22
2025.MAR (37~67) 34
2025.APR (68~134) 45


03 Biology
2024 (135~203) 73
2025.MAR (204~243) 95
2025.APR (244~289) 110


04 Med Term
2024 (290~303) 131
2025.MAR (304~314) 135
2025.APR (315~377) 139


05 English
2024 (378~382) 160
2025.MAR (383~389) 162
2025.APR (390~435) 164

Semmelweis ENtrance Exam

, ADMISSION TOPICS OF SEMMELWEIS UNIVERSITY




Medical biology


1. Structure and functions of proteins. Primary, secondary, tertiary and quaternary structures.
Allostery.
2. Structure and functions of polysaccharides, chemically modified carbohydrates,
glycoproteins and proteoglycans.
3. Structure and functions of glycerolipids (triglycerides and phosphoglycerolipids).
4. Structure and functions of nucleic acids (DNA and different types of RNA). Chromosomes,
genes, alleles, the genetic code.
5. Vitamins. Classification and biologically active derivatives.
6. Reversible inhibition of enzyme activity. Physiological regulation of enzyme activity
(allosteric regulation and covalent modifications).
7. Mechanism of semiconservative DNA replication. DNA polymerases. DNA repair mechanisms.
8. Transcription. The promoter and the initiation of transcription. RNA polymerases.
Regulation of transcription.
9. Processing of eukaryotic mRNA. place and mechanism of translation.
10. Glucose oxidation. Aerobic and anaerobic energy metabolism.
11. Citrate cycle and the oxidative phosphorylation.
12. The origin of life. Chemical evolution, the RNA world. Characteristics of prokaryotic cells.
Bacterial diseases.
13. Compartmentation of eukaryotic sells. Functions of some major cell organelles (nucleus,
nucleolus, mitochondria)
14. Compartmentation of eukaryotic sells. Functions of some major cell organelles (endoplasmic
reticulum, Golgi, lysosomes)
15. The Mendelian laws of inheritance. Sex-linked inheritance. Inheritance of mitochondrial
genes.
16. Control of mitotic cell division, checkpoints in the cell cycle. The role of growth factors.
17. Cellular responses to signals. Cell surface and cytoplasmic/nuclear receptors. G proteins,
second messengers, protein kinase cascades.
18. Endocrine, paracrine and autocrine effects. Hormones, neurohormones and their actions.
Examples (hypothalamus, pituitary gland, adrenal gland, etc.).


Admission topics of Semmelweis University: Medical biology and Medical chemistry 1/3

, 19. Structure and function of the mammalian heart. The cardiac cycle. Generation and
conduction of action potentials.
20. Structure and function of the human respiratory system. Gas exchange in the alveoli.
Transport of oxygen and carbon dioxide in the blood.
21. Structure and function of the human digestive system. The major enzymes of carbohydrate,
protein and lipid digestion. Absorption of nutrients.
22. Structure and function of the human kidney. The nephron. Filtration and reabsorption.
23. Mechanism of muscle contraction, the role of calcium ion. The structure of skeletal
(striated), cardiac and smooth muscle tissues.
24. The nervous tissue. Nerve cells and glial cells. Generation and conduction of neuronal
signals. Resting and action potential.
25. The human reproductive system. Male and female sexual organs and sexual hormones. The
biological role of meiosis.
26. Cellular and humoral immune responses. T and B cells, plasma cells. Major
histocompatibility complex. Immunoglobulins. Active and passive immunizations.
27. General design of viruses. Multiplication of bacteriophages and animal viruses. RNA
replication and reverse transcription.




Medical chemistry


1. General structure of atoms. Chemical elements of the living organisms, their atomic orbitals
and electron configurations.
2. Primary chemical bonds and secondary interactions. Covalent bonds in organic compounds.
3. Physical and chemical properties of water (intermolecular forces, self-ionization, etc.).
4. Solutions. Their components, and types of concentration.
5. Solubility of solid, liquid or gaseous solutes. Precipitation and the solubility product.
6. Acid-base reactions. Definition of pH, the pH scale. Examples for strong and weak acids or
bases.
7. Chemical equilibria, Le Chatelier’s principle, acid-base buffer solutions.
8. Redox reactions. Changes in the oxidation number and transfer of electrons. Voltaic cells.
9. Standard reduction potentials. The effect of temperature, pressure and concentrations on
the reduction potential.
10. Redox reactions and Lewis acid-base reactions of iron and its different ions. The biological
roles of heme.




Admission topics of Semmelweis University: Medical biology and Medical chemistry 2/3

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