MDCB Practice Set 4 - Test 12 2026
A - answer1. Which of the following histologies is the most aggressive with the lowest
survival rate?
A. Glioblastoma
B. Medulloblastoma
C. Ependymoma
D. Juvenile pilocytic astrocytoma
B - answer2. The law of Bergonie and Tribondeau states that ionizing radiation is most
effective against cells
that have a:
A. long mitotic life and not actively mitotic and undifferentiated.
B. long mitotic life and actively mitotic and undifferentiated.
C. short mitotic life and actively mitotic and differentiated.
D. short mitotic life and not actively mitotic and differentiated.
A - answer3. Which of the following is true of Hodgkin's Lymphoma?
A. It is typically seen in young adult patients.
B. It typically involves bone marrow.
C. It does not respond to chemotherapy.
D. It is commonly extranodal in presentation.
C - answer4. In regard to the treatment of soft tissue sarcoma of the extremities, which
one of the following statements is true?
A. Tumor grade and size are less important than histology in determining the radiation
field.
B. The initial large field should encompass just the operative scar with 2 cm margin both
proximally and distally.
C. Radiation therapy post wide excision is suggested to have similar local control as
surgical amputation/disarticulation.
D. Post-operatively, the highest dose that should be given to minimize morbidity is 5000
cGy.
D - answer5. A patient is receiving radiation to the chest. The calculated dose to the
tumor while "on cord" is 35 Gy at 2.5 Gy per fraction. The cord is receiving 3 Gy per
fraction. Assuming alpha/beta of 3 for late effects, what is the cord equivalent dose at 2
Gy per fraction?
A. 35 Gy
B. 40 Gy
C. 45 Gy
D. 50 Gy
, B - answer6. When treating carcinoma of the bladder, the superior border of the
radiation field usually does NOT extend superior to S-1. This is to reduce toxicity to the:
A. pelvic crest.
B. small bowel.
C. kidney.
D. ureters.
B - answer7. The automated delineation of the Biological Target Volume is generated
by using the:
A. Doppler ultrasound to measure blood flow around the target.
B. FDG-PET(CT) and 18F to measure the tissue metabolism.
C. CBCT with equal resolution in all directions.
D. T2 Flair MR image to enhance fluids around the target.
B - answer8. Referring to the MR scan, which structure has the lowest radiation
tolerance dose?
A. #1
B. #2
C. #3
D. #4
C - answer9. The minimum dose required to produce a cataract in a single radiation
exposure is approximately:
A. 10 cGy.
B. 50 cGy.
C. 200 cGy.
D. 500 cGy.
D - answer10. When considering critical structure toxicity, which of the following
statements best describes a serial organ?
A. An organ that can continue to function even if a fraction of its sub-units are critically
damaged.
B. An organ that is radiosensitive.
C. An organ that is radioresistant.
D. An organ that cannot continue to function when a single sub-unit is damaged.
B - answer11. The conventional daily dose for the treatment of a T1 larynx cancer is:
A. 180 cGy.
B. 225 cGy.
C. 250 cGy.
D. 300 cGy.
C - answer12. According to QUANTEC guidelines, what is the percentage rate of optic
neuropathy when treating the optic nerve to a dose greater than 60 Gy with
conventional fractionation?
A. <3%
A - answer1. Which of the following histologies is the most aggressive with the lowest
survival rate?
A. Glioblastoma
B. Medulloblastoma
C. Ependymoma
D. Juvenile pilocytic astrocytoma
B - answer2. The law of Bergonie and Tribondeau states that ionizing radiation is most
effective against cells
that have a:
A. long mitotic life and not actively mitotic and undifferentiated.
B. long mitotic life and actively mitotic and undifferentiated.
C. short mitotic life and actively mitotic and differentiated.
D. short mitotic life and not actively mitotic and differentiated.
A - answer3. Which of the following is true of Hodgkin's Lymphoma?
A. It is typically seen in young adult patients.
B. It typically involves bone marrow.
C. It does not respond to chemotherapy.
D. It is commonly extranodal in presentation.
C - answer4. In regard to the treatment of soft tissue sarcoma of the extremities, which
one of the following statements is true?
A. Tumor grade and size are less important than histology in determining the radiation
field.
B. The initial large field should encompass just the operative scar with 2 cm margin both
proximally and distally.
C. Radiation therapy post wide excision is suggested to have similar local control as
surgical amputation/disarticulation.
D. Post-operatively, the highest dose that should be given to minimize morbidity is 5000
cGy.
D - answer5. A patient is receiving radiation to the chest. The calculated dose to the
tumor while "on cord" is 35 Gy at 2.5 Gy per fraction. The cord is receiving 3 Gy per
fraction. Assuming alpha/beta of 3 for late effects, what is the cord equivalent dose at 2
Gy per fraction?
A. 35 Gy
B. 40 Gy
C. 45 Gy
D. 50 Gy
, B - answer6. When treating carcinoma of the bladder, the superior border of the
radiation field usually does NOT extend superior to S-1. This is to reduce toxicity to the:
A. pelvic crest.
B. small bowel.
C. kidney.
D. ureters.
B - answer7. The automated delineation of the Biological Target Volume is generated
by using the:
A. Doppler ultrasound to measure blood flow around the target.
B. FDG-PET(CT) and 18F to measure the tissue metabolism.
C. CBCT with equal resolution in all directions.
D. T2 Flair MR image to enhance fluids around the target.
B - answer8. Referring to the MR scan, which structure has the lowest radiation
tolerance dose?
A. #1
B. #2
C. #3
D. #4
C - answer9. The minimum dose required to produce a cataract in a single radiation
exposure is approximately:
A. 10 cGy.
B. 50 cGy.
C. 200 cGy.
D. 500 cGy.
D - answer10. When considering critical structure toxicity, which of the following
statements best describes a serial organ?
A. An organ that can continue to function even if a fraction of its sub-units are critically
damaged.
B. An organ that is radiosensitive.
C. An organ that is radioresistant.
D. An organ that cannot continue to function when a single sub-unit is damaged.
B - answer11. The conventional daily dose for the treatment of a T1 larynx cancer is:
A. 180 cGy.
B. 225 cGy.
C. 250 cGy.
D. 300 cGy.
C - answer12. According to QUANTEC guidelines, what is the percentage rate of optic
neuropathy when treating the optic nerve to a dose greater than 60 Gy with
conventional fractionation?
A. <3%
