APEA 3P Exam High Stakes QUESTIONS AND CORRECT
DETAILED ANSWERS LATEST UPDATE THIS YEAR
APEA 3P High Stakes Exam – ANSWER
Exam coverage
APEA 3P High Stakes Exam coverage includes advanced clinical knowledge assessed in the APEA
3P High Stakes Exam provided by Advanced Practice Education Associates (APEA). It focuses on
the three core graduate nursing competencies known as the "3Ps": advanced pathophysiology,
pharmacology, and physical assessment. The exam evaluates understanding of disease
mechanisms, diagnostic reasoning, patient assessment techniques, and appropriate
pharmacologic and non-pharmacologic treatment options. Emphasis is placed on clinical
decision-making, interpretation of patient findings, and the application of evidence-based
practice in the management of common acute and chronic conditions across the lifespan
QUESTION: Taking Pyridium for UTI, what can Pyridium cause? - ANSWER-Hemolytic Anemia
QUESTION: What can PCOS result in? - ANSWER-Increased insulin levels (Hyperinsulinemia),
Androgens, Hirsutism
QUESTION: What would cause decrease in Digoxin levels? - ANSWER-Antacids
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QUESTION: What are the anti-hypertensives used in pregnancy? - ANSWER-Methyldopa (Alpha-
2-Agonist), Labetalol, Nifedipine, Hydralazine
QUESTION: What is a characteristic of Placenta Previa? - ANSWER-Painless, red bleeding
QUESTION: What is a chacteristic of Rheumatoid Arthritis? - ANSWER-Tender, warm, swollen
joints
QUESTION: Medications that can cause ototoxicity? - ANSWER-Aminoglycosides, loop diuretics,
NSAIDs, antihistamines, nasal decongestants
QUESTION: What is the treatment time for enterobiasis? - ANSWER-2 weeks
QUESTION: What does MCV lab value measure? - ANSWER-Mean Corpuscular Volume helps
diagnose different types of anemia such as B12 & Folate (Macrocytic) and Fe anemia
(Microcytic)
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QUESTION: Rhogam is given at how many week gestation? - ANSWER-27-28 weeks
QUESTION: What are Janeway lesions and what do they indicate? - ANSWER-They are irregular,
non-tender hemorrhagic macules located on the hands and feet. Seen in Infective Endocarditis
QUESTION: What are Osler's Nodes and what do they indicate? - ANSWER-They are split pea-
sized, erythematous, tender nodules located on the pads of the fingers and toes. Seen in
Infective Endocarditis
QUESTION: What is the recommendation for Warfarin management when a patient misses a
dose? - ANSWER-If within 12 hours of the dose time, take it. If over 12 hours patient will need a
INR redraw
QUESTION: What do we need to know about ACEs and ARBs? - ANSWER-A dry hacking cough is
a common side effect of ACEs and will go away within a week after discontinuing. ACEs & ARBs
are indicated for patients with DM, CKD, and HTN. Not recommended as 1st line agent with
African Americans & can cause angioedema.
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QUESTION: Contraindications for Hydrochlorothiazide - ANSWER-Sulfa allergy, PCN
hypersensitivity, Asthma, Gout
QUESTION: Systolic Murmurs (Benign) - ANSWER-MR = Mitral Regurge (SOB/Fatigue HF)
Peyton Manning = Physiologic Murmur (Asymptomatic)
AS = Aortic Stenosis (Angina, Syncope HF)
MVP = Mitral Valve Prolapse ("Click", Women 14-30, Palpitations, Chest Pain
QUESTION: Diastolic Murmurs (Abnormal) - ANSWER-AR = Aortic Regurgitation (Angina, HF,
Dizziness, Chest Pain)
MS = Mitral Stenosis (Dyspnea, AFib)
QUESTION: What does S1 indicate? - ANSWER-S1 Closure of the Atrioventricular Valves (Mitral
& Tricuspid Valves)