2025–2026 – Concise High-Yield Review +
Rationales
Physiological Adaptation
Cardiogenic Shock Cardiogenic shock
results from ineffective pumping of the heart,
leading to reduced cardiac output and
perfusion impairment. It is the correct term for
shock related to pump failure. Anaphylactic
shock is from severe allergic reaction with
chemical release. Distributive shock involves
changes in intravascular volume distribution
with usually increased cardiac output.
Myocardial infarction (MI) is not a shock state
itself, though severe MI can lead to
, cardiogenic shock due to damage to the
heart's pumping chamber.
Blood Pressure Regulation by Kidneys
When blood pressure rises, the kidneys
excrete sodium and excess water to reduce
blood volume and lower systolic blood
pressure. This is the normal compensatory
mechanism. Retention of sodium and/or
water increases blood pressure. Sodium and
water move together across kidney
membranes; one cannot be retained or
excreted independently without affecting the
other.
Furosemide (Lasix) in Hypertension
Furosemide is a loop diuretic that inhibits
reabsorption of sodium and water in the loop
of Henle, reducing blood volume and blood