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Metabolism,

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Lecture notes of 13 pages for the course Science at Science (Metabolism pathway)

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Metabolism
Metabolism of carbohydrates and lipids

What is Digestion
A physical and chemical protein in which large food molecules break down into simple
absorbance compound

Digestion and absorption of carbohydrates

●​ • Digestion of carbohydrates begins in the mouth where salivary amylase

(ptyalin) breaks starch into maltose and small dextrins.

●​ • In the stomach, carbohydrate digestion temporarily stops because acidic gastric

juice inactivates salivary amylase.

●​ • In the small intestine, pancreatic amylase continues digestion and converts

remaining starch into maltose, maltotriose, and dextrins.

●​ • Enzymes present on the intestinal brush border such as maltase, sucrase, and

lactase convert disaccharides into monosaccharides.

●​ • Maltase converts maltose into two molecules of glucose.

●​ • Sucrase converts sucrose into glucose and fructose.

●​ • Lactase converts lactose into glucose and galactose.

●​ • Only monosaccharides (glucose, fructose, galactose) are absorbable forms of

carbohydrates.

●​ • Glucose and galactose are absorbed through intestinal epithelial cells by active

transport using sodium-glucose co-transport mechanism.

●​ • Fructose is absorbed by facilitated diffusion without the use of energy.

●​ • Monosaccharides pass from intestinal cells into blood capillaries of the villi.

●​ • Absorbed monosaccharides are transported to the liver through the hepatic

portal vein.

, ●​ • In the liver, excess glucose is converted into glycogen for storage or released

into blood to maintain normal blood glucose level.




Absorption of carbohydrates
1.​ Carbohydrates are absorbed in the small intestine mainly in the jejunum.
2.​ • Only monosaccharides are absorbed; these include glucose, fructose, and
galactose.
3.​ • Glucose is absorbed by active transport with the help of sodium ions through
the intestinal epithelial cells.
4.​ • Galactose is absorbed by the same sodium-dependent active transport
mechanism.
5.​ • Fructose is absorbed by facilitated diffusion without the use of energy.
6.​ • Absorption occurs through the epithelial lining of intestinal villi.
7.​ • Monosaccharides move from intestinal cells into blood capillaries.
8.​ • Blood capillaries carry absorbed sugars to the liver through the hepatic portal
vein.
9.​ • In the liver, monosaccharides are converted into glucose or stored as glycogen.

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