RATED A+ | 2026 | NEW
What is mood?
The pervasive and sustained emo on colouring a person's percep on of the world and ability to
func on in it
What are mood disorders?
Recurrent disturbances or altera ons in mood that cause psychological stress and behavioural
impairment. Characterized by 2 extremes, mania and depression with normal mood in the
centre
What is the most serious complica on of major depressive disorder?
Suicidal thoughts and behaviours. Depression is an abnormal extension or over-elabora on of
sadness and grief
What altera ons in neurotransmi'er levels are commonly associated with major depressive
disorder?
Decreased levels of dopamine, norepinephrine, and serotonin
What primary environmental factor significantly heightens the vulnerability to major depressive
disorder?
Engaging in shi* work, frequent travel, or enduring sleep depriva on. Increased depressed
mood leads to decreased level of physical func oning and increased severity of illness
What are some risk factors for major depressive disorder? (select all that apply)
Female gender, History of depression, Family history of depression, Low socioeconomic status,
Substance abuse. Others include previous suicide a'empts, chronic medical condi ons,
bullying, history of sexual abuse
Which of the following criteria must be met for a diagnosis of major depressive disorder?
Five or more symptoms present in the same 2-week period
Which of the following is not a symptom associated with major depressive disorder?
Elevated self-esteem
, How do the symptoms of major depressive disorder affect an individual's life?
Symptoms cause clinically significant distress or impairment in social, occupa onal, or other
areas of life
Match the type of depression with the correct descrip on.
1. Postpartum depression - Starts within the first month a*er childbirth, can last weeks to
months, & can develop into a chronic episode of depression
2. Catatonia - Unresponsiveness, extreme psychomotor retarda on, withdrawal, nega vity
3. Persistent depressive disorder (dysthymia) - Chronically low mood, with some moderate
symptoms of depression
4. Depression with psychosis - Disorganized thinking, hallucina ons or delusion of guilt
5. Seasonal affec ve disorder (SAD) - Coincides with changes in the season
6. Atypical depression - 'Reversed vegeta ve' symptoms (increased sleep, increased appe te
and weight)
Co-Exis ng Condi on with Depression
Anxiety
Secondary Diagnoses with Depression
Schizophrenia, Obsessive Compulsive Disorder, Chronic Physical Illnesses
Pharmacotherapies for Depression
Tricyclic, Norepinephrine Dopamine Reuptake Inhibitors, Serotonin and Norepinephrine Re-
Uptake Inhibitors (SNRI), Selec ve Serotonin Re-Uptake Inhibitors (SSRIs), Monoamine Oxidase
Inhibitors (MAOIs)
An depressant Symptom Relief Time
1 to 4 weeks
Tricyclic An depressant Full Effect Time
4-8 weeks
Tricyclic An depressant Mechanism of Ac on
Blocking the uptake of monoamines by the pre-synap c neuron
Effect of Tricyclic An depressants in Synap c Cle*
Increased neurotransmi'er levels - Norepinephrine and Serotonin