These study materials of Pharmacology-I are designed to solidify the mainstays of Medical
students' drug action, pharmacokinetics and pharmacodynamics. Studies should begin with
Unit-I (General Pharmacology), where special emphasis is placed on agonists, antagonists,
and ADME (Absorption, Distribution, Metabolism, Excretion) processes.
Unit-II has to focus on pharmacodynamics, receptor theories and clinical trials. Then the
role of the peripheral and central nervous system in Unit-III and IV, especially
neurotransmission and various neurotransmitters (e.g. GABA, Dopamine), must be
understood. Lastly, Unit-V discusses the drugs of psychopharmacological agents and
diseases such as Parkinson's or Alzheimer's. It is important to read text as well as follow
mechanistic diagrams and drug classification tables for better results.
1
, UNIT-I
General Pharmacology
Introduction to Pharmacology
Definition
Historical landmarks and scope of pharmacology
Nature and source of drugs
Essential drugs concept and routes of drug administration
Agonists
Antagonists( competitive and non-competitive)
Spare receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, Allergy.
Pharmacokinetics
Membrane transport
Absorption
Distribution
Metabolism and excretion of drugs
Enzyme induction
Enzyme inhibition
Kinetics of elimination 2
,3
, 4
students' drug action, pharmacokinetics and pharmacodynamics. Studies should begin with
Unit-I (General Pharmacology), where special emphasis is placed on agonists, antagonists,
and ADME (Absorption, Distribution, Metabolism, Excretion) processes.
Unit-II has to focus on pharmacodynamics, receptor theories and clinical trials. Then the
role of the peripheral and central nervous system in Unit-III and IV, especially
neurotransmission and various neurotransmitters (e.g. GABA, Dopamine), must be
understood. Lastly, Unit-V discusses the drugs of psychopharmacological agents and
diseases such as Parkinson's or Alzheimer's. It is important to read text as well as follow
mechanistic diagrams and drug classification tables for better results.
1
, UNIT-I
General Pharmacology
Introduction to Pharmacology
Definition
Historical landmarks and scope of pharmacology
Nature and source of drugs
Essential drugs concept and routes of drug administration
Agonists
Antagonists( competitive and non-competitive)
Spare receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, Allergy.
Pharmacokinetics
Membrane transport
Absorption
Distribution
Metabolism and excretion of drugs
Enzyme induction
Enzyme inhibition
Kinetics of elimination 2
,3
, 4
