Cushing Syndrome (symptoms)
Hypersecretion of adrenal cortex, mainly cortisol
Round moon-shaped face with acne.
Muscle weakness
Purple striated marks on skin
Hirsutism
Head and trunk grossly exaggerated
Pencil-thin arms and legs
Buffalo hump on upper back
Peptic ulcer
Hypertension
Susceptibility to infection
Anxiety and depression
Cushing Syndrome (treatment)
,Restore concentration of serum cortisol to normal levels
Varies according to the etiology
Drugs or radiation to suppress adrenocorticotropic hormone
(ACTH)
Total adrenalectomy
Lifelong treatments of cortisol replacement therapy
Surgery followed by chemotherapy when the syndrome is
caused by tumors of the adrenal cortex
Acromegaly (Growth hormone imbalance)
Hyper-secretion of growth hormone (GH) during adulthood
Fusion of growth plates at the ends of long bones which
prevents a person from growing taller
Widening and enlargement of facial features, jaw, hands, and
feet.
Acromegaly (Growth hormone imbalance) (Treatment)
Drug therapy
Growth Hormone
Surgery if a tumor is the cause
Gigantism (Growth hormone imbalance)
, Hypersecretion of GH during childhood
Excessive growth of bones and tissues due to high level of GH
Height changes of up to 6 inches in 1 year in children.
Adrupt development, resulting in abnormally increased height.
Gigantism (growth hormone imbalance) (treatment)
Drug therapy to suppress secretion of growth hormone
Surgery to remove an adenoma or radiation therapy to destroy
the adenoma
Dwarfism (Growth Hormone Imbalance)(treatment)
Hypo-secretion of GH during childhood
Lack of growth and short stature but with normal body
proportions.
Diabetes Mellitus
a group of metabolic diseases characterized by hyperglycemia
resulting from defects in insulin secretion, insulin action, or both
Type 1 (insulin-dependent) Diabetes mellitus
Chronic metabolic disorder marked by hyperglycemia. Inability
of the pancreas to produce enough insulin to properly control
blood glucose levels. Most commonly diagnosed in children,
adolescents, or young adults.