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PN HESI Pharmacology Exam 2026 Review
Test Bank 180 Questions with Correct
Answers, Detailed Rationales, and Table of
Contents Evolve HESI PN Pharmacology
Exam Review – Complete A+ Guide
TABLE OF CONTENTS
Section Topic Area Question
Section 1 Medication Administration & Safety 1-20
Section 2 Cardiovascular Medications 21-40
Section 3 Respiratory Medications 41-50
Endocrine Medications (Diabetes &
Section 4 51-65
Thyroid)
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Section Topic Area Question
Section 5 Neurological & Psychiatric Medications 66-85
Section 6 Pain Management & Antidotes 86-100
Section 7 Antibiotics & Anti-infectives 101-115
Section 8 Gastrointestinal Medications 116-130
Section 9 Diuretics & Renal Medications 131-140
Section
Anticoagulants & Hematological Agents 141-150
10
Section 11 Women's Health & Prenatal Medications 151-160
Section 12 Antidotes & Emergency Medications 161-170
Section 13 Geriatric Pharmacology Considerations 171-180
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SECTION 1: MEDICATION ADMINISTRATION & SAFETY
QUESTION 1
How do you safely prepare medication?
A. Prepare in a busy area to save time
B. Have good lighting and work alone, checking the
medication label three times
C. Transfer medications to unlabeled bottles for
convenience
D. Prepare medications for multiple patients at once
Answer: B. Have good lighting and work alone, checking
the medication label three times
Rationale: Safe medication preparation requires good
lighting, working alone without distractions, and
checking the medication label three times: when
removing it from the drawer, before dispensing, and
when replacing the container . Never use unlabeled
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bottles, never transfer medications to other
containers, and always check expiration dates .
QUESTION 2
How would you administer medication via the
intramuscular (IM) route?
A. Inject at a 15-degree angle using a ½-inch needle
B. Inject at a 90-degree angle using the Z-track method
C. Inject at a 45-degree angle into fatty tissue
D. Inject intradermally and raise a wheal
Answer: B. Inject at a 90-degree angle using the Z-track
method
Rationale: IM injections are administered at a 90-
degree angle. The Z-track method is recommended to
prevent medication leakage into subcutaneous tissue
and to minimize irritation . The ventrogluteal site is
preferred for adults due to its distance from major
nerves and blood vessels .
PN HESI Pharmacology Exam 2026 Review
Test Bank 180 Questions with Correct
Answers, Detailed Rationales, and Table of
Contents Evolve HESI PN Pharmacology
Exam Review – Complete A+ Guide
TABLE OF CONTENTS
Section Topic Area Question
Section 1 Medication Administration & Safety 1-20
Section 2 Cardiovascular Medications 21-40
Section 3 Respiratory Medications 41-50
Endocrine Medications (Diabetes &
Section 4 51-65
Thyroid)
,2|Page
Section Topic Area Question
Section 5 Neurological & Psychiatric Medications 66-85
Section 6 Pain Management & Antidotes 86-100
Section 7 Antibiotics & Anti-infectives 101-115
Section 8 Gastrointestinal Medications 116-130
Section 9 Diuretics & Renal Medications 131-140
Section
Anticoagulants & Hematological Agents 141-150
10
Section 11 Women's Health & Prenatal Medications 151-160
Section 12 Antidotes & Emergency Medications 161-170
Section 13 Geriatric Pharmacology Considerations 171-180
,3|Page
SECTION 1: MEDICATION ADMINISTRATION & SAFETY
QUESTION 1
How do you safely prepare medication?
A. Prepare in a busy area to save time
B. Have good lighting and work alone, checking the
medication label three times
C. Transfer medications to unlabeled bottles for
convenience
D. Prepare medications for multiple patients at once
Answer: B. Have good lighting and work alone, checking
the medication label three times
Rationale: Safe medication preparation requires good
lighting, working alone without distractions, and
checking the medication label three times: when
removing it from the drawer, before dispensing, and
when replacing the container . Never use unlabeled
, 4|Page
bottles, never transfer medications to other
containers, and always check expiration dates .
QUESTION 2
How would you administer medication via the
intramuscular (IM) route?
A. Inject at a 15-degree angle using a ½-inch needle
B. Inject at a 90-degree angle using the Z-track method
C. Inject at a 45-degree angle into fatty tissue
D. Inject intradermally and raise a wheal
Answer: B. Inject at a 90-degree angle using the Z-track
method
Rationale: IM injections are administered at a 90-
degree angle. The Z-track method is recommended to
prevent medication leakage into subcutaneous tissue
and to minimize irritation . The ventrogluteal site is
preferred for adults due to its distance from major
nerves and blood vessels .
