UROGENITAL FLAGELLATES, AND HEMOFLAGELLATES
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What is Giardia duodenalis formerly known as? Answer: Giardia lamblia and Giardia
intestinalis
What condition is caused by Giardia duodenalis? Answer: Gastroenteritis and traveler's
diarrhea
Who is at risk for Giardia duodenalis infection? Answer: Travelers from endemic areas,
hikers drinking untreated water, children in daycare, and swimmers in contaminated
pools.
How long can Giardia cysts remain viable in cold water? Answer: Several months
What is a common name for the condition caused by Giardia duodenalis? Answer:
Beaver fever or backpacker's diarrhea
How few cysts can initiate a Giardia duodenalis infection? Answer: As few as 10 cysts
What triggers the excystation of Giardia duodenalis? Answer: Gastric acid in the
stomach
What stimulates the growth of Giardia duodenalis trophozoites? Answer: Presence of
carbohydrates and bile
What are the clinical symptoms of Giardia duodenalis infection? Answer: Self-limiting
diarrhea, malaise, cramps, nausea, and abdominal tenderness.
What is the typical incubation period for Giardia duodenalis? Answer: 12 to 14 days
What is the usual diagnostic specimen for Giardia duodenalis? Answer: Feces
Describe the morphology of Giardia duodenalis trophozoites. Answer: Pear or teardrop
shaped, bilaterally symmetric, with 2 nuclei and 4 pairs of flagella.
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, What is a unique motility characteristic of Giardia duodenalis trophozoites? Answer:
Characteristic 'falling leaf' motility in a wet mount.
What is the cyst morphology of Giardia duodenalis? Answer: Oval shape with 4 nuclei
and a 'halo effect' around the cyst wall.
What is Dientamoeba fragilis often mistaken for? Answer: Amebae, but it is a flagellate.
What is the trophozoite morphology of Dientamoeba fragilis? Answer: Binucleate with a
delicate nuclear membrane and no peripheral chromatin.
What is the primary pathogen of the urogenital tract? Answer: Trichomonas vaginalis
How is Trichomonas vaginalis transmitted? Answer: Via direct contact; it cannot survive
outside the urogenital system.
What are common symptoms of Trichomonas vaginalis infection in women? Answer:
Itching, frothy vaginal discharge, and dysuria.
What test is used to diagnose Trichomonas vaginalis? Answer: Amine (whiff) test with
KOH added to vaginal discharge.
What is the characteristic motility of Trichomonas vaginalis trophozoites? Answer:
Jerky motility in a wet mount.
Describe the morphology of Chilomastix mesnili trophozoites. Answer: Pear shaped
with a prominent nucleus and a 'shepherd's crook' appearance.
What is the cyst morphology of Chilomastix mesnili? Answer: Lemon shaped with a
clear hyaline knob at the end.
What is Pentatrichomonas hominis formerly known as? Answer: Trichomonas hominis
What distinguishes blood and tissue flagellates from intestinal flagellates? Answer:
They are transmitted by insect vectors and have different life cycle stages.
What are the four morphologic forms associated with Leishmania and Trypanosoma?
Answer: Amastigote, promastigote, epimastigote, and trypomastigote.
Name one species complex of Leishmania that causes disease in humans. Answer:
Leishmania tropica, Leishmania mexicana, Leishmania braziliensis, or Leishmania
donovani.
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