NSG 5140 Advanced Hematology Case Study: RBC Physiology, Iron Deficiency Anemia, Vitamin B12 Deficiency, Pernicious Anemia, Folic Acid Deficiency, Hemolytic Anemia, Sickle Cell Disease, Aplastic Anemia, Bone Marrow Suppression, Erythropoiesis, Reticulocyt

NSG 5140 Advanced Hematology Case Study: RBC Physiology, Iron Deficiency Anemia, Vitamin B12 Deficiency, Pernicious Anemia, Folic Acid Deficiency, Hemolytic Anemia, Sickle Cell Disease, Aplastic Anemia, Bone Marrow Suppression, Erythropoiesis, Reticulocyte Count, Hemoglobin Synthesis, Macrocytic Microcytic Normocytic Anemias, Hypochromic RBCs, Iron Studies, Ferritin, Transferrin Saturation, Total Iron Binding Capacity, CBC Interpretation, Electrolyte Imbalances, Hypokalemia, Hypomagnesemia, Telemetry, Oxygen Therapy, Blood Loss Anemia, Transfusion Protocols, Cyanocobalamin Therapy, Nutritional Management, Pain Management, Opioid Safety, Patient Education, Psychosocial Considerations, Interprofessional Collaboration, Clinical Decision-Making Exam Questions Verified and Provided with Complete A+ Graded Rationales Latest Updated 2026 Ingredients to make RBCs -Iron -B12 -Intrinsic factor -Folic acid Production of RBCs Bone marrow is signaled by kidney via the secretion of erythropoietin to make RBC RBCs carry oxygen! Hgb binds to the oxygen to carry it to the tissues General S/S of Anemia -Pallor -Fatigue, change in energy level -Irritability -Weakness -Palpitations -Presyncope -Cold hands/feet -Dyspnea on exertion -SOB -Tachycardia -Pallor of nails, mucus membranes -Changes in vital signs: increased RR, increased HR -Chest pain NOTE: As anemia worsens, symptoms exacerbate "Rule of Three" -RBC x3 = Hgb -Hgb x3 = Hct -Can go backwards: Hct/3 = Hgb Blood Loss Anemia Causes -Trauma -Surgery -GI bleeding -Internal bleeding -Can be acute or chronic. Chronic leads to iron deficiency