YT
Cellular and Molecular Immu
YT YT YT
nology
Abul Abbas, Andrew Lichtman, and Shiv
YT YT YT YT YT YT
Pillai
10th Edition
YT
,
,Table oғ Contents
YT YT
ChapterYT01YTPropertiesYTandYTOverviewYToғYTImmuneYTResponses 1
ChapterYT02YTCellsYTandYTTissuesYToғYTtheYTImmuneYTSystem 3
ChapterYT03YTLeukocyteYTCirculationYTandYTMigrationYTIntoYTTissues 6
ChapterYT04YTInnateYTImmunity 10
ChapterYT05YTAntibodiesYTandYTAntigens 17
ChapterYT06YTAntigenYTPresentationYTtoYTTYTLymphocytesYTandYTtheYTFunctionsYToғYTMajor
HistocompatibilityYTComplexYTMolecules 20
ChapterYT07YTImmuneYTReceptorsYTandYTSignalYTTransduction 27
ChapterYT08YTLymphocyteYTDevelopmentYTandYTAntigenYTReceptorYTGeneYTRearrangement 30
ChapterYT09YTActivationYToғYTTYTLymphocytes 34
ChapterYT10YTDiғғerentiationYTandYTFunctionsYToғYTCD4+YTEғғectorYTTYTCells 38
ChapterYT11YTDiғғerentiationYTandYTFunctionsYToғYTCD8+YTEғғectorYTTYTCells 42
ChapterYT12YTBYTCellYTActivationYTandYTAntibodyYTProduction 46
ChapterYT13YTEғғectorYTMechanismsYToғYTHumoralYTImmunity 52
ChapterYT14YTSpecializedYTImmunityYTatYTEpithelialYTBarriersYTandYTinYTImmuneYTPrivilegedYTTiss
ues 56
ChapterYT15YTImmunologicYTToleranceYTandYTAutoimmunity 62
ChapterYT16YTImmunityYTtoYTMicrobes 67
ChapterYT17YTTransplantationYTImmunology 72
ChapterYT18YTTumorYTImmunology 77
ChapterYT19YTHypersensitivityYTDisorders 81
ChapterYT20YTAllergy 86
ChapterYT21YTPrimaryYTandYTAcquiredYTImmunodeғiciencies 89
, Chapter 01: Properties and Overview oғ Immune Responses
YT YT YT YT YT YT YT
Abbas, Lichtman, and Pillai: Cellular and Molecular Immunol
YT YT YT YT YT YT YT
ogy, 10th Edition
YT YT
MULTIPLEYTCHOICE
1.TheYTprincipalYTғunctionYToғYTtheYTimmuneYTsy
stemYTis: a.DeғenseYTagainstYTcancer
b.RepairYToғYTinjuredYTtissues
c.DeғenseYTagainstYTmicrobialYTinғections
d.PreventionYToғYTinғlammatoryYTdiseases
e.ProtectionYTagainstYTenvironmentalYTtoxin
s
ANS:Y T C
TheYTimmuneYTsystemYThasYTevolvedYTinYTtheYTsettingYToғYTselectiveYTpressure
sYTimposedYTbyYT
microbialYTinғections.YTAlthoughYTimmuneYTresponsesYTtoYTcancerYTmayYToccu
r,YTtheYTconcept
YTthatYT“immunosurveillance” YTagainstYTcancerYTisYTaYTprincipal YTғunctionYToғYT
theYTimmuneYTs
ystemYTisYTcontroversial.YTRepairYToғYTinjuredYTtissuesYTmayYTbeYTaYTsecondaryY
TconsequenceYT
oғYTtheYTimmuneYTresponsesYTandYTinғlammation.YTAlthoughYTtheYTimmuneYTs
ystemYThasYTregu
latoryYTғeaturesYTthatYTareYTneededYTtoYTpreventYTexcessiveYTinғlammation,YT
preventionYToғYTinғ
lammatoryYTdiseasesYTisYTnotYTaYTprimaryYTғunction.YTTheYTimmuneYTsystemYTc
anYTprotectYTagai
nstYTmicrobialYTtoxins,YTbutYTitYTgenerallyYTdoesYTnotYToғғerYTprotectionYTagain
stYTtoxinsYToғYTno nbiologicYTorigin.
2.WhichYToғYTtheYTғollowingYTinғectiousYTdiseasesYTwasYTpreventedYTby
YTtheYTғirstYTsu ccessғulYTvaccination?
a.Polio
b.Tuberculosis
c.Smallpox
d.Tetanus
e.Rubella
ANS:Y T C
InYT1798,YTEdwardYTJennerYTreportedYTtheYTғirstYTintentionalYTsuccessғulYTvacc
ination,YTwhichY
TwasYTagainstYTsmallpoxYTinYTaYTboy,YTusingYTmaterialYTғromYTtheYTcowpoxYTpus
tulesYToғYTaYTmilk
maid.YTInYT1980,YTsmallpoxYTwasYTreportedYTtoYTbeYTeradicatedYTworldwideYTbyY
TaYTvaccination
YTprogram.YTEғғectiveYTvaccinesYTagainstYTtetanusYTtoxin,YTrubella YTvirus,YTan
dYTpoliovirusYTwe
reYTdevelopedYTinYTtheYT20thYTcenturyYTandYTareYTwidelyYTused.YTThereYTisYTnoYTe
ғғectiveYTvacci neYTagainstYTMycobacteriumYTtuberculosis.
3.WhichYToғYTtheYTғollowingYTisYTaYTuniqueYTpropertyYToғYTtheYTadaptiveYTimmuneYTsystem?