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Family Medicine Step 2 (COMLEX/USMLE) – 200 Questions – MSK, Infectious Disease, Endocrinology, OB/GYN Q&A 2026

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This document is a high-yield Family Medicine overview containing approximately 200 rapid-review clinical questions and answers tailored for Step 2 (USMLE) and COMLEX Level 2-CE preparation. It covers a broad spectrum of primary care topics including musculoskeletal conditions, infectious diseases, endocrinology, cardiology, pulmonology, dermatology, pediatrics, obstetrics and gynecology, and preventive medicine. Early sections (pages 1–4) emphasize musculoskeletal diagnoses such as rotator cuff injuries, bursitis, fractures, and pediatric orthopedic conditions, while later sections expand into systemic diseases including diabetes management, thyroid disorders, tuberculosis treatment, COPD/asthma protocols, and rheumatologic conditions. The document integrates high-yield clinical pearls, diagnostic criteria, and treatment algorithms commonly tested on board exams. It includes essential concepts such as antibiotic selection (e.g., C. difficile, PID, CAP), screening guidelines (e.g., breast cancer, lung cancer, prenatal labs), cardiovascular risk management (statins, LDL targets), and endocrine disorders (e.g., Graves, Hashimoto, PCOS). Additionally, it highlights emergency and inpatient topics such as septic arthritis, COPD exacerbations, postpartum hemorrhage, and neonatal fever management, along with pharmacologic mechanisms and side effects (e.g., colchicine, metformin, thiazides). The concise Q&A format supports active recall, making it highly effective for rapid revision and exam-focused study. This resource is highly relevant for courses such as Family Medicine Clerkship, Primary Care Medicine, Internal Medicine, Pediatrics, Obstetrics & Gynecology, and Preventive Medicine. It is ideal for medical students (MBBS, MD, DO programs), particularly those preparing for USMLE Step 2 CK, COMLEX Level 2-CE, and Family Medicine COMAT exams. It is also suitable for physician assistant (PA) students, nursing students, and international medical graduates seeking a concise yet comprehensive primary care review. The content aligns closely with widely used board preparation textbooks such as First Aid for the USMLE Step 2 CK and Step-Up to Medicine, making it a valuable supplementary resource for consolidating high-yield concepts, improving clinical reasoning, and maximizing exam performance. Keywords: family medicine, step 2, COMLEX level 2, USMLE step 2 CK, primary care, musculoskeletal, infectious disease, endocrinology, pediatrics, obstetrics, gynecology, screening guidelines, diabetes, thyroid disorders, COPD, asthma, clinical questions, board exam preparation

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Institution
Family Medicine
Course
Family medicine

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HY Family Medicine Overview -
Step 2 Level 2

Subacromial Bursitis - 🧠 ANSWER ✔✔Pain during arm raising (repetitive

overhead motion).


Rotator Cuff Injury - 🧠 ANSWER ✔✔Pain during arm lifting above head or

when lying on the side.


Subscapularis Injury - 🧠 ANSWER ✔✔Positive Gerber lift-off test.


Supraspinatus Injury - 🧠 ANSWER ✔✔Positive 'empty can' or 'full can' test

(90-degree abduction).

,Infraspinatus/Teres Minor Injury - 🧠 ANSWER ✔✔Pain during lateral

rotation resistance; 'Pitcher injury' often indicates infraspinatus.


Olecranon Bursitis - 🧠 ANSWER ✔✔Pain after leaning on the elbow.


Lateral Epicondylitis (Tennis Elbow) - 🧠 ANSWER ✔✔Pain in lateral

forearm with resistance to elbow extension. Treatment: Forearm strap.


Medial Epicondylitis (Golfer's Elbow) - 🧠 ANSWER ✔✔Pain in medial

forearm with resistance to elbow flexion. Treatment: Forearm strap.


deQuervain Tenosynovitis - 🧠 ANSWER ✔✔Lateral wrist pain in

breastfeeding women; Diagnosed with Finkelstein test. Treatment:

Immediate steroid injection.


Ganglion Cyst - 🧠 ANSWER ✔✔Lump on dorsum of hand, painless, mobile.

Treatment: Needle drainage.


Colles Fracture - 🧠 ANSWER ✔✔Wrist fracture with posterior displacement

of radius.


Smith Fracture - 🧠 ANSWER ✔✔Wrist fracture with anterior displacement

of radius.

,Monteggia Fracture - 🧠 ANSWER ✔✔Proximal ulnar fracture with anterior

displacement of radial head.


Galeazzi Fracture - 🧠 ANSWER ✔✔Radial shaft fracture with displacement

of the distal radioulnar joint.


Greenstick Fracture - 🧠 ANSWER ✔✔Bone bends but doesn't fully break

(common in children).


Child Abuse Indicators - 🧠 ANSWER ✔✔Spiral or posterior rib fractures.


Trochanteric Bursitis - 🧠 ANSWER ✔✔Hip pain when lying on the side.


Greater Trochanteric Syndrome - 🧠 ANSWER ✔✔Lateral hip pain when

palpated/abducting/standing.


Meralgia Paresthetica - 🧠 ANSWER ✔✔Lateral thigh pain (lateral femoral

cutaneous nerve entrapment).


Tibia Vara (Blount Disease) - 🧠 ANSWER ✔✔Bowing of legs; differentiating

from rickets.


Hip Dysplasia - 🧠 ANSWER ✔✔In infants, 'clicking/clunking' with positive

Ortolani and Barlow tests.



COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2026. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED

, Legg-Calve-Perthes - 🧠 ANSWER ✔✔6-9-year-old boy with painful limp (x-

ray showing contracted capital epiphysis).


Meniscal Tear - 🧠 ANSWER ✔✔'Locking' or 'catching' of the knee.


Anserine Bursitis - 🧠 ANSWER ✔✔Pain in the medial knee.


Iliotibial Band Syndrome - 🧠 ANSWER ✔✔Pain in the lateral knee.


Patellofemoral Syndrome - 🧠 ANSWER ✔✔Pain during stairs or long sitting;

high BMI. Management: Quadriceps strengthening + RICE.


Patellar Tendonitis (Jumper's Knee) - 🧠 ANSWER ✔✔Pain in the anterior

knee (common in athletes). Management: Quadriceps strengthening +

RICE.


Osgood-Schlatter - 🧠 ANSWER ✔✔Knee pain in active teens (repeated

avulsion microfractures).


Septic Arthritis Indicators - 🧠 ANSWER ✔✔Red, warm, tender knee. Next

Step: Joint aspiration.


Toxic Synovitis - 🧠 ANSWER ✔✔Post-viral hip pain in children;

differentiated from septic arthritis (Kocher criteria negative).

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Institution
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Course
Family medicine

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