YT
Cellular and Molecular Immu
YT YT YT
noloɡy
Abul Abbas, Andrew Lichtman, and Shiv
YT YT YT YT YT YT
Pillai
10th Edition
YT
,
,Table of Contents
YT YT
ChapterYT01YTPropertiesYTandYTOverviewYTofYTImmuneYTResponses 1
ChapterYT02YTCellsYTandYTTissuesYTofYTtheYTImmuneYTSystem 3
ChapterYT03YTLeukocyteYTCirculationYTandYTMiɡrationYTIntoYTTissues 6
ChapterYT04YTInnateYTImmunity 10
ChapterYT05YTAntibodiesYTandYTAntiɡens 17
ChapterYT06YTAntiɡenYTPresentationYTtoYTTYTLymphocytesYTandYTtheYTFunctionsYTofYTMajor
HistocompatibilityYTComplexYTMolecules 20
ChapterYT07YTImmuneYTReceptorsYTandYTSiɡnalYTTransduction 27
ChapterYT08YTLymphocyteYTDevelopmentYTandYTAntiɡenYTReceptorYTGeneYTRearranɡement 30
ChapterYT09YTActivationYTofYTTYTLymphocytes 34
ChapterYT10YTDifferentiationYTandYTFunctionsYTofYTCD4+YTEffectorYTTYTCells 38
ChapterYT11YTDifferentiationYTandYTFunctionsYTofYTCD8+YTEffectorYTTYTCells 42
ChapterYT12YTBYTCellYTActivationYTandYTAntibodyYTProduction 46
ChapterYT13YTEffectorYTMechanismsYTofYTHumoralYTImmunity 52
ChapterYT14YTSpecializedYTImmunityYTatYTEpithelialYTBarriersYTandYTinYTImmuneYTPrivileɡedYTTiss
ues 56
ChapterYT15YTImmunoloɡicYTToleranceYTandYTAutoimmunity 62
ChapterYT16YTImmunityYTtoYTMicrobes 67
ChapterYT17YTTransplantationYTImmunoloɡy 72
ChapterYT18YTTumorYTImmunoloɡy 77
ChapterYT19YTHypersensitivityYTDisorders 81
ChapterYT20YTAllerɡy 86
ChapterYT21YTPrimaryYTandYTAcquiredYTImmunodeficiencies 89
, Chapter 01: Properties and Overview of Immune Responses
YT YT YT YT YT YT YT
Abbas, Lichtman, and Pillai: Cellular and Molecular Immunol
YT YT YT YT YT YT YT
oɡy, 10th Edition
YT YT
MULTIPLEYTCHOICE
1.TheYTprincipalYTfunctionYTofYTtheYTimmuneYTsys
temYTis: a.DefenseYTaɡainstYTcancer
b.RepairYTofYTinjuredYTtissues
c.DefenseYTaɡainstYTmicrobialYTinfections
d.PreventionYTofYTinflammatoryYTdiseases
e.ProtectionYTaɡainstYTenvironmentalYTtoxin
s
ANS:Y T C
TheYTimmuneYTsystemYThasYTevolvedYTinYTtheYTsettinɡYTofYTselectiveYTpressures
YTimposedYTbyYT
microbialYTinfections.YTAlthouɡhYTimmuneYTresponsesYTtoYTcancerYTmayYToccu
r,YTtheYTconcept
YTthatYT“immunosurveillance” YTaɡainstYTcancerYTisYTaYTprincipal YTfunctionYTofYTt
heYTimmuneYTs
ystemYTisYTcontroversial.YTRepairYTofYTinjuredYTtissuesYTmayYTbeYTaYTsecondaryYT
consequenceYT
ofYTtheYTimmuneYTresponsesYTandYTinflammation.YTAlthouɡhYTtheYTimmuneYTsy
stemYThasYTreɡu
latoryYTfeaturesYTthatYTareYTneededYTtoYTpreventYTexcessiveYTinflammation,YTp
reventionYTofYTinf
lammatoryYTdiseasesYTisYTnotYTaYTprimaryYTfunction.YTTheYTimmuneYTsystemYTc
anYTprotectYTaɡai
nstYTmicrobialYTtoxins,YTbutYTitYTɡenerallyYTdoesYTnotYTofferYTprotectionYTaɡains
tYTtoxinsYTofYTno nbioloɡicYToriɡin.
2.WhichYTofYTtheYTfollowinɡYTinfectiousYTdiseasesYTwasYTpreventedYTbyYT
theYTfirstYTsu ccessfulYTvaccination?
a.Polio
b.Tuberculosis
c.Smallpox
d.Tetanus
e.Rubella
ANS:Y T C
InYT1798,YTEdwardYTJennerYTreportedYTtheYTfirstYTintentionalYTsuccessfulYTvacci
nation,YTwhichY
TwasYTaɡainstYTsmallpoxYTinYTaYTboy,YTusinɡYTmaterialYTfromYTtheYTcowpoxYTpust
ulesYTofYTaYTmilk
maid.YTInYT1980,YTsmallpoxYTwasYTreportedYTtoYTbeYTeradicatedYTworldwideYTbyY
TaYTvaccination
YTproɡram.YTEffectiveYTvaccinesYTaɡainstYTtetanusYTtoxin,YTrubella YTvirus,YTandY
Tpoliovirus YTwe
reYTdevelopedYTinYTtheYT20thYTcenturyYTandYTareYTwidelyYTused.YTThereYTisYTnoYTe
ffectiveYTvacci neYTaɡainstYTMycobacteriumYTtuberculosis.
3.WhichYTofYTtheYTfollowinɡYTisYTaYTuniqueYTpropertyYTofYTtheYTadaptiveYTimmuneYTsystem?