CORRECT ANSWERS GRADED A+
• EPTS (estimates post transplant survival score).
Answer: Receives After 18 years old, represents percentage of kidney
candidates in the nation with a longer expected post transplant survival time.
• treatment of AMR s/p lung tx.
Answer: rituximab
• Why are induction agents given pre- or intraoperatively in transplant?.
Answer: Decrease incidence of acute rejection delay first rejection delay use
of calcineurin inhibitors due to their nephrotixicity
• Tacrolimus (Prograf).
Answer: Do not take before lab draw, taken bid, side effects include HTN,
dyslipidemia, headache, diarrhea, nausea, tremor, hair loss (alopecia),
hyperglycemia, changes in kidney function(nephrotoxic), adrenal
insufficiency, DM *tac toxicity-tremors, especially in hands,
leukoencephalopathy- mental status changes stop dc n Med
• S&S of rejection post liver TX.
Answer: Fever, ictera(yellowing of sclera), jaundice, RUQ pain, fatigue,
malaise, pruritis *confirmed by biopsy
• Cvp range post pancreas transplant.
Answer: 5-10
• What is treatment for HAT?.
Answer: Immediate return to OR for revascularization of organ
• Most common post-op pediatrics complication in liver tx.
Answer: HAT, diagnosed with US. Sx include elevated transaminases and
bilirubin, change in MS, biliary leak, sepsis. return to OR for thrombectomy.
May need re-transplant.
,• Early Indicators of non functioning liver:.
Answer: decrease in bile production extreme edema of organ Abnormal
color of organ upon reperfusion(mottled, gray, pale) lack of reperfusion in
OR urine output <30ml/hr hemodynamically unstable glucose, k, and lactate
abnormalities Coagulopathy
• OPTN 15.5B Discovery of recipient disease or malignancy.
Answer: Notify OPO or LD recovery hospital by phone of findings ASAp
within 24hrs. Report event thru UNOS pt safety portalASAp w/n 24 hrs of
learning of event. provide additional info or specimens as requested.
• CMV prophylaxis.
Answer: Valganciclovir ( valcyte) for 3 months
• Which medication causes increased cholesterol levels?.
Answer: Sirolimis(rapamycin/rapamune)
• Symptoms of bleeding post liver transplant include:.
Answer: Increased swelling in abdomen Pallor Clinical manifestations of
hypovolemia
• Sx of pneumonia in heart or lung tx.
Answer: persistent respiratory failure, failure to wean from vent, fever,
purulent secretions, lung consolidation Dx respiratory tract cx, CT scan
• Acute Liver Failure: Non MELD scores.
Answer: Condition for status 1A (18 years at registration, life expectancy <
7 days and one of the following-Fulminant Liver failure w/o pre-existing
liver disease in ICU, on vent, dialysis or CVVHD, INR > 2.0 Anhepatic
• Xenotransplant.
Answer: Transplant from another species
• Clinical indications of vascular thrombosis in pancreas transplant recipients.
Answer: Abrupt rise in glucose, sharp rise in serum amylase or lipase,
tenderness or pain over graft site in BD recipients: massive hematuria,
decrease or absence of urine amylase levels,
, • What can a rise in ALP post liver tx indicate?.
Answer: Can be a sign of biliary complications or cholestasis
• Corticosteroids.
Answer: Methylprednisolone (solu-medrol), or IV or Oral prednisone
• Budd Chari syndrome.
Answer: thrombosis of the portal vein SX-abdominal pain, ascites,
hepatomegaly
• Side effects of calcineurin inhibitors(tacrolimus and cyclosporine).
Answer: Tremors, headaches, HTN, nephrotoxicity, high glucose levels, hair
growth or loss, increased risk of cancer
• COPD: Emphysema.
Answer: most common indication for lung tx
• What can cause a post liver transplant patient whose initial postop
neurological course is normal to develop sudden deterioration in
neurological status?.
Answer: Intracranial bleed
• What can lead to hypoxic ischemic encephalopathy post liver transplant?.
Answer: Significant peri-operative hypotension
• Clinical manifestations of cholestasis.
Answer: Cloy or white stools Dark urine Itching Pain in upper right
quadrant Jaundice Inability to digest certain foods N&V
• Which organ is risk for infection post transplant greatest?.
Answer: Lung-
• CMV clinical manifestations.
Answer: High fever, rigors, body aches, night sweats
• CMV infection manifestations.
Answer: fever fatigue malaise leukopenia thrombocytopenia elevated LFTs
GI sx