MBI 111 EXAM 1 QUESTIONS AND
ANSWERS GRADED A+ 2026
Antoine van Leewenhoek (1600s) - ANS developed simple microscopes, looked at fabric, "The
Father of MBI", called bacteria "weeanimalcules"
Ignaz Semmelweis (1840s) - ANS suspected that doctors were transmitting childbed fever to
women during childbirth, required hand washing in chlorine solution
John Snow (1850s) - ANS cholera, found that 500 fatal cases occurred in 10 days within 2500
yds. of a certain intersection, shut down the broad street pump and identified the link b/n
cholera and water
Joseph Lister (1860s) - ANS followed up on infection control work by Semmelweis, used
carbolic acid (phenol) to clean surgical dressings and instruments to control infections,
cleanliness could control disease
Louis Pasteur (1860-1880s) - ANS microbes are everywhere, food spoilage, heat can kill
microbes, suspected that microbes could cause disease and microbes too weak to cause disease
could cause immunity
Robert Koch - ANS Germ Theory of Disease, developed techniques for growing bacteria in the
lab, Koch's postulates, discovered the bacterial causes for tuberculosis and cholera
Guy de Chauliac - ANS Black Plague survivor, advised Pope Clement, cured plague by air
purification, venesection, and healthy diet
@COPYRIGHT 2026/2027 ALLRIGHTS RESERVED 1
, Edward Jenner - ANS noted that milkmaids who had developed cowpox seemed protected
from smallpox, inoculation results in immunity-prevented disease
Leprosy - ANS a skin and nerve disease caused by mycobacterium leprae bacteria (2 forms)
Tuberculoid Leprosy - ANS (Type of leprosy) shallow, irregular skin lesions, some loss of
sensation due to damage in nerves in affected areas
Lepromatous Leprosy - ANS (type of leprosy) disfiguring disease, significant nerve damage
occurs which can lead to serious unrecognized injuries
Leprosy's Long Term Impact - ANS -diseases can be contagious
-isolation can be used as prevention
-certain diseases stigmatize those affected
Plague - ANS a complex disease that can affect multiple organs, caused by Y. pests bacteria
(3-forms)
Bubonic Plague - ANS (form of plague) Y. Pestis bacteria are transmitted by rats to humans by
rat flea bites
-lymph nodes become infected, swell and become neurotic ("bubos")
-fever, chills, headache
Septicemic "Black" Plague - ANS (form of plague) Occurs when Y. pests bacteria spreads from
the lymph nodes to the bloodstream
-immune system has inappropriate reaction to endotoxin Y. pests
-intravascular coagulation/septic shock (hands turn black)
@COPYRIGHT 2026/2027 ALLRIGHTS RESERVED 2
ANSWERS GRADED A+ 2026
Antoine van Leewenhoek (1600s) - ANS developed simple microscopes, looked at fabric, "The
Father of MBI", called bacteria "weeanimalcules"
Ignaz Semmelweis (1840s) - ANS suspected that doctors were transmitting childbed fever to
women during childbirth, required hand washing in chlorine solution
John Snow (1850s) - ANS cholera, found that 500 fatal cases occurred in 10 days within 2500
yds. of a certain intersection, shut down the broad street pump and identified the link b/n
cholera and water
Joseph Lister (1860s) - ANS followed up on infection control work by Semmelweis, used
carbolic acid (phenol) to clean surgical dressings and instruments to control infections,
cleanliness could control disease
Louis Pasteur (1860-1880s) - ANS microbes are everywhere, food spoilage, heat can kill
microbes, suspected that microbes could cause disease and microbes too weak to cause disease
could cause immunity
Robert Koch - ANS Germ Theory of Disease, developed techniques for growing bacteria in the
lab, Koch's postulates, discovered the bacterial causes for tuberculosis and cholera
Guy de Chauliac - ANS Black Plague survivor, advised Pope Clement, cured plague by air
purification, venesection, and healthy diet
@COPYRIGHT 2026/2027 ALLRIGHTS RESERVED 1
, Edward Jenner - ANS noted that milkmaids who had developed cowpox seemed protected
from smallpox, inoculation results in immunity-prevented disease
Leprosy - ANS a skin and nerve disease caused by mycobacterium leprae bacteria (2 forms)
Tuberculoid Leprosy - ANS (Type of leprosy) shallow, irregular skin lesions, some loss of
sensation due to damage in nerves in affected areas
Lepromatous Leprosy - ANS (type of leprosy) disfiguring disease, significant nerve damage
occurs which can lead to serious unrecognized injuries
Leprosy's Long Term Impact - ANS -diseases can be contagious
-isolation can be used as prevention
-certain diseases stigmatize those affected
Plague - ANS a complex disease that can affect multiple organs, caused by Y. pests bacteria
(3-forms)
Bubonic Plague - ANS (form of plague) Y. Pestis bacteria are transmitted by rats to humans by
rat flea bites
-lymph nodes become infected, swell and become neurotic ("bubos")
-fever, chills, headache
Septicemic "Black" Plague - ANS (form of plague) Occurs when Y. pests bacteria spreads from
the lymph nodes to the bloodstream
-immune system has inappropriate reaction to endotoxin Y. pests
-intravascular coagulation/septic shock (hands turn black)
@COPYRIGHT 2026/2027 ALLRIGHTS RESERVED 2
