NURS 5461 Exam 1 Questions And
Correct Answers
Microcytic anemia
iron deficiency, usually due to malabsorption / occult blood loss, or lead
poisoning. MCV <80
Normocytic anemia
due to hemorrhage or chronic disease. Aplastic anemia. MVC 80-92
macrocytic anemia
due to folate or vitamin B12(cobalamin) deficiency (megaloblastic anemia) /
pernicious anemia. /liver diseases
serum ferritin
Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron levels will
eventually fall.
,Anemia of chronic disease
NORMOcytic anemia with ↓ serum iron, ↓ TIBC, and normal iron stores. Treat with
epoetin and give an iron supplement
Schistocytes
Associated with hemolytic uremia syndrome
pernicious anemia
Macrocytic anemia caused by vitamin B12 deficiency. B12 is essential to
maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and
histamine2 blockers can cause this.
Increased homocysteine & methylmalonic acid level indicates ?
B12 deficiency
increased homocysteine levels
Folate deficiency
Sperocytes
, Appear as spheres, lack central pallor, smaller diameter, indicate immune-
mediated process - can be seen after blood transfusion
aplastic anemia
a normocytic anemia characterized by the failure of bone marrow to produce red
blood cells
Low ferritin
iron deficiency anemia
Transferrin
transports iron
TIBC (total iron binding capacity)
Available transferrin that is left unbound (Represents the "empty seats on a
train"). When iron is low, TIBC will be high. When iron is high, TIBC will be low
MCHC (mean corpuscular hemoglobin concentration)
32 - 36 g/dL
Correct Answers
Microcytic anemia
iron deficiency, usually due to malabsorption / occult blood loss, or lead
poisoning. MCV <80
Normocytic anemia
due to hemorrhage or chronic disease. Aplastic anemia. MVC 80-92
macrocytic anemia
due to folate or vitamin B12(cobalamin) deficiency (megaloblastic anemia) /
pernicious anemia. /liver diseases
serum ferritin
Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron levels will
eventually fall.
,Anemia of chronic disease
NORMOcytic anemia with ↓ serum iron, ↓ TIBC, and normal iron stores. Treat with
epoetin and give an iron supplement
Schistocytes
Associated with hemolytic uremia syndrome
pernicious anemia
Macrocytic anemia caused by vitamin B12 deficiency. B12 is essential to
maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and
histamine2 blockers can cause this.
Increased homocysteine & methylmalonic acid level indicates ?
B12 deficiency
increased homocysteine levels
Folate deficiency
Sperocytes
, Appear as spheres, lack central pallor, smaller diameter, indicate immune-
mediated process - can be seen after blood transfusion
aplastic anemia
a normocytic anemia characterized by the failure of bone marrow to produce red
blood cells
Low ferritin
iron deficiency anemia
Transferrin
transports iron
TIBC (total iron binding capacity)
Available transferrin that is left unbound (Represents the "empty seats on a
train"). When iron is low, TIBC will be high. When iron is high, TIBC will be low
MCHC (mean corpuscular hemoglobin concentration)
32 - 36 g/dL
