1|Page
HESI RN PHARMACOLOGY NGN Version 1,2 &3
Newest 2026-2027 With Complete All Questions And
Correct Detailed Answers| Brand New Version!
VERSION 1
1. Which technique would a nurse reinforce when teaching a client how to self-administer eye
drops after cataract surgery?
a. placing the drops on the cornea of the eye
b. raising the upper eyelid with a gentle traction
c. holding the dropper tip above the conjunctive sac
d. squeezing the eye shut after installing the medication
Answer c. Holding the dropper tip above the conjunctive sac
Rationale
Drops are placed within the lower lid (conjunctival sac) to protect against physical injury and infection,
the dropper tip should not touch the eye. The lower lid is retracted for placement of eye drops.
Squeezing the eyes shut after administration of the medication should be avoided as this will squeeze
medication out of the eye.
2. Which medication is indicated to evacuate the uterus for a miscarriage?
a. Clomiphene
b. Dinoprostone
c. Magnesium sulfate
d. Methylergonovine
Answer b. Dinoprostone
Rationale
Dinoprostone is a prostaglandin abortifacient and cervical ripening drug, which is indicated for uterine
evacuation in cases of miscarriage. Clomiphene is indicated for female infertility in some clients.
Magnesium sulfate is used to treat preeclampsia. Methylergonovine is used to treat postpartum
uterine atony and hemorrhage.
3. Which preparation uses toxoids but not live viruses? Select all that apply. One, some, or all
responses may be correct.
a. Rotarix
b. Varivax
c. M-M-R II
d. PEDIARIX
e. DAPTACEL
Answer d. PEDRIX and e. DAPTACEL
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Rationale
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PEDIARIX consists of diphtheria and tetanus toxoids plus inactivated bacterial components of
pertussis, inactive viral agent of hepatitis B, and inactivated poliovirus vaccine. DAPTACEL is a
preparation consisting of toxoids plus inactive bacterial and viral components of depth area and
, 4|Page
tetanus toxoids and acellular pertussis vaccine. Rotarix, Varivax, and M-M-R II are preparations
containing live viruses.
4. Which vaccination may be responsible for the development of thrombocytopenia in a four-year-
old child?
a. Rotavirus vaccine
b. B. Varicella virus vaccine
c. Human Papillomavirus vaccine
d. Measles, mumps, and rubella virus vaccine (MMR)
Answer d. Measles, mumps, and rubella virus vaccine (MMR)
Rationale
Measles, mumps, and rubella virus vaccine (MMR) may cause transient thrombocytopenia it occurs
only rarely and is generally benign. Rotavirus vaccine carries a small risk for intussusception. Varicella
virus vaccine and human papilloma virus vaccine may cause mild effects such as fever and fainting.
5. Which is the best response to the mother of an infant who asks “My aunt said to wipe my baby's
gums with wine to ease the pain of teething. What do you suggest?”
a. “Make sure the wine is diluted before applying to the gums”
b. Your aunt means well, but that’s not a good idea”
c. You can use a teething gel that contains benzocaine to control the pain.”
d. “Offer something to chew on, such as a rubber teether.”
Answer d. “Offer something to chew on, such as a rubber teether.”
Rationale
Providing information is a nonjudgmental way to address unsafe childcare practices. Benzocaine can
result in methemoglobinemia, which has resulted in a warning to avoid its use in children younger
than 24 months. Alcohol ingestion is contraindicated and illegal for all children. Being judgmental
about the aunt’s approach may close communication; The nurse should offer acceptable alternatives.
6. Which adverse effect of heparin may be seen during pregnancy?
a. Osteoporosis
b. Severe bleeding
c. Abnormal uterine contractions
d. Suppression of uterine contractions
Answer a. Osteoporosis
Rationale
Heparin is safe for a fetus but may cause osteoporosis in a pregnant woman. Severe bleeding and
abnormal or suppress uterine contractions are not associated with heparin.
7. Which drug is a teratogen that may cause masculinization of a female fetus?
a. Lithium
HESI RN PHARMACOLOGY NGN Version 1,2 &3
Newest 2026-2027 With Complete All Questions And
Correct Detailed Answers| Brand New Version!
VERSION 1
1. Which technique would a nurse reinforce when teaching a client how to self-administer eye
drops after cataract surgery?
a. placing the drops on the cornea of the eye
b. raising the upper eyelid with a gentle traction
c. holding the dropper tip above the conjunctive sac
d. squeezing the eye shut after installing the medication
Answer c. Holding the dropper tip above the conjunctive sac
Rationale
Drops are placed within the lower lid (conjunctival sac) to protect against physical injury and infection,
the dropper tip should not touch the eye. The lower lid is retracted for placement of eye drops.
Squeezing the eyes shut after administration of the medication should be avoided as this will squeeze
medication out of the eye.
2. Which medication is indicated to evacuate the uterus for a miscarriage?
a. Clomiphene
b. Dinoprostone
c. Magnesium sulfate
d. Methylergonovine
Answer b. Dinoprostone
Rationale
Dinoprostone is a prostaglandin abortifacient and cervical ripening drug, which is indicated for uterine
evacuation in cases of miscarriage. Clomiphene is indicated for female infertility in some clients.
Magnesium sulfate is used to treat preeclampsia. Methylergonovine is used to treat postpartum
uterine atony and hemorrhage.
3. Which preparation uses toxoids but not live viruses? Select all that apply. One, some, or all
responses may be correct.
a. Rotarix
b. Varivax
c. M-M-R II
d. PEDIARIX
e. DAPTACEL
Answer d. PEDRIX and e. DAPTACEL
,2|Page
Rationale
,3|Page
PEDIARIX consists of diphtheria and tetanus toxoids plus inactivated bacterial components of
pertussis, inactive viral agent of hepatitis B, and inactivated poliovirus vaccine. DAPTACEL is a
preparation consisting of toxoids plus inactive bacterial and viral components of depth area and
, 4|Page
tetanus toxoids and acellular pertussis vaccine. Rotarix, Varivax, and M-M-R II are preparations
containing live viruses.
4. Which vaccination may be responsible for the development of thrombocytopenia in a four-year-
old child?
a. Rotavirus vaccine
b. B. Varicella virus vaccine
c. Human Papillomavirus vaccine
d. Measles, mumps, and rubella virus vaccine (MMR)
Answer d. Measles, mumps, and rubella virus vaccine (MMR)
Rationale
Measles, mumps, and rubella virus vaccine (MMR) may cause transient thrombocytopenia it occurs
only rarely and is generally benign. Rotavirus vaccine carries a small risk for intussusception. Varicella
virus vaccine and human papilloma virus vaccine may cause mild effects such as fever and fainting.
5. Which is the best response to the mother of an infant who asks “My aunt said to wipe my baby's
gums with wine to ease the pain of teething. What do you suggest?”
a. “Make sure the wine is diluted before applying to the gums”
b. Your aunt means well, but that’s not a good idea”
c. You can use a teething gel that contains benzocaine to control the pain.”
d. “Offer something to chew on, such as a rubber teether.”
Answer d. “Offer something to chew on, such as a rubber teether.”
Rationale
Providing information is a nonjudgmental way to address unsafe childcare practices. Benzocaine can
result in methemoglobinemia, which has resulted in a warning to avoid its use in children younger
than 24 months. Alcohol ingestion is contraindicated and illegal for all children. Being judgmental
about the aunt’s approach may close communication; The nurse should offer acceptable alternatives.
6. Which adverse effect of heparin may be seen during pregnancy?
a. Osteoporosis
b. Severe bleeding
c. Abnormal uterine contractions
d. Suppression of uterine contractions
Answer a. Osteoporosis
Rationale
Heparin is safe for a fetus but may cause osteoporosis in a pregnant woman. Severe bleeding and
abnormal or suppress uterine contractions are not associated with heparin.
7. Which drug is a teratogen that may cause masculinization of a female fetus?
a. Lithium
